| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 10273 |
Name | STUB1 |
Synonym | CHIP|HSPABP2|NY-CO-7|SCAR16|SDCCAG7|UBOX1;STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase;STUB1;STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase |
Definition | CLL-associated antigen KW-8|E3 ubiquitin-protein ligase CHIP|antigen NY-CO-7|carboxy terminus of Hsp70-interacting protein|heat shock protein A binding protein 2 (c-terminal)|serologically defined colon cancer antigen 7 |
Position | 16p13.3 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 15937 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Protein processing in endoplasmic reticulum;KEGG PATHWAY;hsa04141 |
Pathway | Ubiquitin mediated proteolysis;KEGG PATHWAY;hsa04120 |
Pathway | Parkinson disease;PANTHER;P00049 |
Pathway | Alpha-synuclein signaling;PID Curated;200187 |
Disease | Alzheimer's disease;FunDO |
Disease | Neurodegenerative disorder;FunDO |
Disease | Spinocerebellar ataxias;FunDO |
|
External Links |
|
Links to Entrez Gene | 10273 |
Links to all GeneRIF Items | 10273 |
Links to iHOP | 10273 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>10273 : length: 912 atgaagggcaaggaggagaaggagggcggcgcacggctgggcgctggcggcggaagcccc gagaagagcccgagcgcgcaggagctcaaggagcagggcaatcgtctgttcgtgggccga aagtacccggaggcggcggcctgctacggccgcgcgatcacccggaacccgctggtggcc gtgtattacaccaaccgggccttgtgctacctgaagatgcagcagcacgagcaggccctg gccgactgccggcgcgccctggagctggacgggcagtctgtgaaggcgcacttcttcctg gggcagtgccagctggagatggagagctatgatgaggccatcgccaatctgcagcgagct tacagcctggccaaggagcagcggctgaacttcggggacgacatccccagcgctcttcga atcgcgaagaagaagcgctggaacagcattgaggagcggcgcatccaccaggagagcgag ctgcactcctacctctccaggctcattgccgcggagcgtgagagggagctggaagagtgc cagcgaaaccacgagggtgatgaggacgacagccacgtccgggcccagcaggcctgcatt gaggccaagcacgacaagtacatggcggacatggacgagcttttttctcaggtggatgag aagaggaagaagcgagacatccccgactacctgtgtggcaagatcagctttgagctgatg cgggagccgtgcatcacgcccagtggcatcacctacgaccgcaaggacatcgaggagcac ctgcagcgtgtgggtcattttgaccccgtgacccggagccccctgacccaggaacagctc atccccaacttggctatgaaggaggttattgacgcattcatctctgagaatggctgggtg gaggactactga |
Protein Sequence |
>10273 : length: 303 MKGKEEKEGGARLGAGGGSPEKSPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVA VYYTNRALCYLKMQQHEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRA YSLAKEQRLNFGDDIPSALRIAKKKRWNSIEERRIHQESELHSYLSRLIAAERERELEEC QRNHEGDEDDSHVRAQQACIEAKHDKYMADMDELFSQVDEKRKKRDIPDYLCGKISFELM REPCITPSGITYDRKDIEEHLQRVGHFDPVTRSPLTQEQLIPNLAMKEVIDAFISENGWV EDY |