| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 10395 |
Name | DLC1 |
Synonym | ARHGAP7|HP|STARD12|p122-RhoGAP;DLC1 Rho GTPase activating protein;DLC1;DLC1 Rho GTPase activating protein |
Definition | Rho-GTPase-activating protein 7|START domain-containing protein 12|StAR-related lipid transfer (START) domain containing 12|deleted in liver cancer 1 protein|deleted in liver cancer 1 variant 2|rho GTPase-activating protein 7|rho-type GTPase-activating pr |
Position | 8p22 |
Gene Type | protein-coding |
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TSG scores |
Description |
| TUSON ranking | 5985 |
TUSON P-value | 1 |
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Pathways and Diseases |
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Pathway | Signaling by Rho GTPases;Reactome;REACT:11044 |
Pathway | phospholipase c delta in phospholipid associated cell signaling;PID BioCarta;100071 |
Pathway | PDGF signaling pathway;PANTHER;P00047 |
Pathway | Regulation of RhoA activity;PID Curated;200050 |
Disease | Cancer;FunDO |
Disease | Colorectal cancer, somatic;OMIM |
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External Links |
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Links to Entrez Gene | 10395 |
Links to all GeneRIF Items | 10395 |
Links to iHOP | 10395 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>10395 : length: 3054 atgaagctagaaattagtcctcatcggaaacgaagtgacgattcagacgaggatgagcct tgtgccatcagtggcaaatggactttccaaagggacagcaagaggtggtcccggcttgaa gagtttgatgtcttttctccaaaacaagacctggtccctgggtccccagacgactcccac ccgaaggacggccccagccccggaggcacgctgatggacctcagcgagcgccaggaggtg tcttccgtccgcagcctcagcagcactggcagcctccccagccacgcgccccccagcgag gatgctgccaccccccggactaactccgtcatcagcgtttgctcctccagcaacttggca ggcaatgacgactctttcggcagcctgccctctcccaaggaactgtccagcttcagcttc agcatgaaaggccacgaaaaaactgccaagtccaagacgcgcagtctgctgaaacggatg gagagcctgaagctcaagagctcccatcacagcaagcacaaagcgccctcaaagctgggg ttgatcatcagcgggcccatcttgcaagaggggatggatgaggagaagctgaagcagctc aactgcgtggagatctccgccctcaatggcaaccgcatcaacgtccccatggtacgaaag aggagcgtttccaactccacgcagaccagcagcagcagcagccagtcggagaccagcagc gcggtcagcacgcccagccctgttacgaggacccggagcctcagtgcgtgcaacaagcgg gtgggcatgtacttagagggcttcgatcctttcaatcagtcaacatttaacaacgtggtg gagcagaactttaagaaccgcgagagctacccagaggacacggtgttctacatccctgaa gatcacaagcctggcactttccccaaagctctcaccaatggcagtttctccccctcgggg aataacggctctgtgaactggaggacgggaagcttccacggccctggccacatcagcctc aggagggaaaacagtagcgacagccccaaggaactgaagagacgcaattcttccagctcc atgagcagccgcctgagcatctacgacaacgtgccgggctccatcctctactccagttca ggggacctggcggatctggagaacgaggacatcttccccgagctggacgacatcctctac cacgtgaaggggatgcagcggatagtcaatcagtggtcggagaagttttctgatgaggga gattcggactcagccctggactcggtctctccctgcccgtcctctccaaaacagatacac ctggatgtggacaacgaccgaaccacacccagcgacctggacagcacaggcaactccctg aatgaaccggaagagccctccgagatcccggaaagaagggattctggggttggggcttcc ctaaccaggtccaacaggcaccgactgagatggcacagtttccagagctcacatcggcca agcctcaactctgtatcactacagattaactgccagtctgtggcccagatgaacctgctg cagaaatactcactcctaaagctaacggccctgctggagaaatacacaccttctaacaag catggttttagctgggccgtgcccaagttcatgaagaggatcaaggttccagactacaag gaccggagtgtgtttggggtcccactgacggtcaacgtgcagcgcacaggacaaccgttg cctcagagcatccagcaggccatgcgatacctccggaaccattgtttggatcaggttggg ctcttcagaaaatcgggggtcaagtcccggattcaggctctgcgccagatgaatgaaggt gccatagactgtgtcaactacgaaggacagtctgcttatgacgtggcagacatgctgaag cagtattttcgagatcttcctgagccactaatgacgaacaaactctcggaaacctttcta cagatctaccaatatgtgcccaaggaccagcgcctgcaggccatcaaggctgccatcatg ctgctgcctgacgagaaccgggaggttctgcagaccctgctttatttcctgagcgatgtc acagcagccgtaaaagaaaaccagatgaccccaaccaacctggccgtgtgcttagcgcct tccctcttccatctcaacaccctgaagagagagaattcctctcccagggtaatgcaaaga aaacaaagtttgggcaaaccagatcagaaagatttgaatgaaaacctagctgccactcaa gggctggcccatatgatcgccgagtgcaagaagcttttccaggttcccgaggaaatgagc cgatgtcgtaattcctataccgaacaagagctgaagcccctcactctggaagcactcggg cacctgggtaatgatgactcagctgactaccaacacttcctccaggactgtgtggatggc ctgtttaaagaagtcaaagagaagtttaaaggctgggtcagctactccacttcggagcag gctgagctgtcctataagaaggtgagcgaaggaccccctctgaggctttggaggtcagtc attgaagtccctgctgtgccagaggaaatcttaaagcgcctacttaaagaacagcacctc tgggatgtagacctgttggattcaaaagtgatcgaaattctggacagccaaactgaaatt taccagtatgtccaaaacagtatggcacctcatcctgctcgagactacgttgttttaaga acctggaggactaatttacccaaaggagcctgtgcccttttactaacctctgtggatcac gatcgcgcacctgtggtgggtgtgagggttaatgtgctcttgtccaggtatttgattgaa ccctgtgggccaggaaaatccaaactcacctacatgtgcagagttgacttaaggggccac atgccagaatggtacacaaaatcttttggacatttgtgtgcagctgaagttgtaaagatc cgggattccttcagtaaccagaacactgaaaccaaagacaccaaatctaggtga |
Protein Sequence |
>10395 : length: 1017 MKLEISPHRKRSDDSDEDEPCAISGKWTFQRDSKRWSRLEEFDVFSPKQDLVPGSPDDSH PKDGPSPGGTLMDLSERQEVSSVRSLSSTGSLPSHAPPSEDAATPRTNSVISVCSSSNLA GNDDSFGSLPSPKELSSFSFSMKGHEKTAKSKTRSLLKRMESLKLKSSHHSKHKAPSKLG LIISGPILQEGMDEEKLKQLNCVEISALNGNRINVPMVRKRSVSNSTQTSSSSSQSETSS AVSTPSPVTRTRSLSACNKRVGMYLEGFDPFNQSTFNNVVEQNFKNRESYPEDTVFYIPE DHKPGTFPKALTNGSFSPSGNNGSVNWRTGSFHGPGHISLRRENSSDSPKELKRRNSSSS MSSRLSIYDNVPGSILYSSSGDLADLENEDIFPELDDILYHVKGMQRIVNQWSEKFSDEG DSDSALDSVSPCPSSPKQIHLDVDNDRTTPSDLDSTGNSLNEPEEPSEIPERRDSGVGAS LTRSNRHRLRWHSFQSSHRPSLNSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPSNK HGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVG LFRKSGVKSRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFL QIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAP SLFHLNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEMS RCRNSYTEQELKPLTLEALGHLGNDDSADYQHFLQDCVDGLFKEVKEKFKGWVSYSTSEQ AELSYKKVSEGPPLRLWRSVIEVPAVPEEILKRLLKEQHLWDVDLLDSKVIEILDSQTEI YQYVQNSMAPHPARDYVVLRTWRTNLPKGACALLLTSVDHDRAPVVGVRVNVLLSRYLIE PCGPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVVKIRDSFSNQNTETKDTKSR |