Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

10395

Name

DLC1

Synonymous

ARHGAP7|HP|STARD12|p122-RhoGAP;DLC1 Rho GTPase activating protein;DLC1;DLC1 Rho GTPase activating protein

Definition

Rho-GTPase-activating protein 7|START domain-containing protein 12|StAR-related lipid transfer (START) domain containing 12|deleted in liver cancer 1 protein|deleted in liver cancer 1 variant 2|rho GTPase-activating protein 7|rho-type GTPase-activating pr

Position

8p22

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

DLC1(h) --> dlc1-isoform2(h) (expression).
DLC1(h) --> dlc1(h) (expression).
EEF1A(r) + dlc1-isoform1(h) <==> EEF1A(r):dlc1-isoform1(h) (binding)
EEF1A(h) + dlc1-isoform1(h) <==> EEF1A(h):dlc1-isoform1(h) (binding)
dlc1-isoform1(h) + EEF1A(h) <==> dlc1-isoform1(h):EEF1A(h) (binding)
C1-TEN-isoform1(h) + dlc1-isoform1(h) <==> C1-TEN-isoform1(h):dlc1-isoform1(h) (binding)
DLC1(h) --> dlc1-isoform1(h) (expression).
DLC1(h) --> dlc1-isoform3(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

304Phosphoserine (By similarity).Swiss-Prot 53.0
305Phosphoserine (By similarity).Swiss-Prot 53.0
310Phosphoserine (By similarity).Swiss-Prot 53.0
312Phosphothreonine (By similarity).Swiss-Prot 53.0
313Phosphoserine (By similarity).Swiss-Prot 53.0
317Phosphoserine (By similarity).Swiss-Prot 53.0
318Phosphothreonine (By similarity).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr8

Promoter: 13034680 - 13036680Agilent_014791

chr8

Promoter: 13416266 - 13418266GoldenGate_Methylation_Cancer_Panel_I

chr8

Promoter: 13416266 - 13418266GoldenGate_Methylation_Cancer_Panel_I

chr8

Promoter: 13034680 - 13036680GSE27584

chr8

Promoter: 13034680 - 13036680Agilent_014791_44K

chr8

Promoter: 13034680 - 13036680Agilent_014791

chr8

Promoter: 13034680 - 13036680PMID:15911247

chr8

Promoter: 13416266 - 13418266PMID:15911247

chr8

Promoter: 13416266 - 13418266PMID:15911247

chr8

Promoter: 13034680 - 13036680PMID:16435073

chr8

Promoter: 13416266 - 13418266PMID:16435073

chr8

Promoter: 13416266 - 13418266PMID:16435073

chr8

Promoter: 13034680 - 13036680PMID:16774933

chr8

Promoter: 13416266 - 13418266PMID:16774933

chr8

Promoter: 13416266 - 13418266PMID:16774933

chr8

Promoter: 13034680 - 13036680PMID:16862168

chr8

Promoter: 13416266 - 13418266PMID:16862168

chr8

Promoter: 13416266 - 13418266PMID:16862168

chr8

Promoter: 13034680 - 13036680PMID:12645648

chr8

Promoter: 13416266 - 13418266PMID:12645648

chr8

Promoter: 13416266 - 13418266PMID:12645648

chr8

Promoter: 13034680 - 13036680PMID:15201975

chr8

Promoter: 13416266 - 13418266PMID:15201975

chr8

Promoter: 13416266 - 13418266PMID:15201975

chr8

Promoter: 13034680 - 13036680PMID:16533763

chr8

Promoter: 13416266 - 13418266PMID:16533763

chr8

Promoter: 13416266 - 13418266PMID:16533763

chr8

Promoter: 13034680 - 13036680PMID:12813468

chr8

Promoter: 13416266 - 13418266PMID:12813468

chr8

Promoter: 13416266 - 13418266PMID:12813468

chr8

Promoter: 13034680 - 13036680PMID:16489177

chr8

Promoter: 13416266 - 13418266PMID:16489177

chr8

Promoter: 13416266 - 13418266PMID:16489177

chr8

Promoter: 13034680 - 13036680PMID:17029774

chr8

Promoter: 13416266 - 13418266PMID:17029774

chr8

Promoter: 13416266 - 13418266PMID:17029774


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