| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 10397 |
Name | NDRG1 |
Synonym | CAP43|CMT4D|DRG-1|DRG1|GC4|HMSNL|NDR1|NMSL|PROXY1|RIT42|RTP|TARG1|TDD5;N-myc downstream regulated 1;NDRG1;N-myc downstream regulated 1 |
Definition | N-myc downstream-regulated gene 1 protein|differentiation-related gene 1 protein|nickel-specific induction protein Cap43|protein NDRG1|protein regulated by oxygen-1|reducing agents and tunicamycin-responsive protein |
Position | 8q24.3 |
Gene Type | protein-coding |
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TSG scores |
Description |
| TUSON ranking | 11215 |
TUSON P-value | 1 |
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Pathways and Diseases |
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Pathway | Validated targets of C-MYC transcriptional repression;PID Curated;200171 |
Pathway | Direct p53 effectors;PID Curated;200101 |
Pathway | HIF-1-alpha transcription factor network;PID Curated;200172 |
Disease | Charcot-Marie-Tooth disease;FunDO |
Disease | Cancer;FunDO |
Disease | Charcot-Marie-Tooth disease, type 4D;OMIM |
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External Links |
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Links to Entrez Gene | 10397 |
Links to all GeneRIF Items | 10397 |
Links to iHOP | 10397 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>10397 : length: 1185 atgtctcgggagatgcaggatgtagacctcgctgaggtgaagcctttggtggagaaaggg gagaccatcaccggcctcctgcaagagtttgatgtccaggagcaggacatcgagacttta catggctctgttcacgtcacgctgtgtgggactcccaagggaaaccggcctgtcatcctc acctaccatgacatcggcatgaaccacaaaacctgctacaaccccctcttcaactacgag gacatgcaggagatcacccagcactttgccgtctgccacgtggacgcccctggccagcag gacggcgcagcctccttccccgcagggtacatgtacccctccatggatcagctggctgaa atgcttcctggagtccttcaacagtttgggctgaaaagcattattggcatgggaacagga gcaggcgcctacatcctaactcgatttgctctaaacaaccctgagatggtggagggcctt gtccttatcaacgtgaacccttgtgcggaaggctggatggactgggccgcctccaagatc tcaggatggacccaagctctgccggacatggtggtgtcccacctttttgggaaggaagaa atgcagagtaacgtggaagtggtccacacctaccgccagcacattgtgaatgacatgaac cccggcaacctgcacctgttcatcaatgcctacaacagccggcgcgacctggagattgag cgaccaatgccgggaacccacacagtcaccctgcagtgccctgctctgttggtggttggg gacagctcgcctgcagtggatgccgtggtggagtgcaactcaaaattggacccaacaaag accactctcctcaagatggcggactgtggcggcctcccgcagatctcccagccggccaag ctcgctgaggccttcaagtacttcgtgcagggcatgggatacatgccctcggctagcatg acccgcctgatgcggtcccgcacagcctctggttccagcgtcacttctctggatggcacc cgcagccgctcccacaccagcgagggcacccgaagccgctcccacaccagcgagggcacc cgcagccgctcgcacaccagcgagggggcccacctggacatcacccccaactcgggtgct gctgggaacagcgccgggcccaagtccatggaggtctcctgctag |
Protein Sequence |
>10397 : length: 394 MSREMQDVDLAEVKPLVEKGETITGLLQEFDVQEQDIETLHGSVHVTLCGTPKGNRPVIL TYHDIGMNHKTCYNPLFNYEDMQEITQHFAVCHVDAPGQQDGAASFPAGYMYPSMDQLAE MLPGVLQQFGLKSIIGMGTGAGAYILTRFALNNPEMVEGLVLINVNPCAEGWMDWAASKI SGWTQALPDMVVSHLFGKEEMQSNVEVVHTYRQHIVNDMNPGNLHLFINAYNSRRDLEIE RPMPGTHTVTLQCPALLVVGDSSPAVDAVVECNSKLDPTKTTLLKMADCGGLPQISQPAK LAEAFKYFVQGMGYMPSASMTRLMRSRTASGSSVTSLDGTRSRSHTSEGTRSRSHTSEGT RSRSHTSEGAHLDITPNSGAAGNSAGPKSMEVSC |