| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 1490 |
Name | CTGF |
Synonym | CCN2|HCS24|IGFBP8|NOV2;connective tissue growth factor;CTGF;connective tissue growth factor |
Definition | CCN family member 2|IBP-8|IGF-binding protein 8|IGFBP-8|hypertrophic chondrocyte-specific protein 24|insulin-like growth factor-binding protein 8 |
Position | 6q23.1 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 5501 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | TGF-beta receptor signaling;PID Curated;200195 |
Pathway | Metabolism of lipids and lipoproteins;Reactome;REACT:22258 |
Pathway | amb2 Integrin signaling;PID Curated;200108 |
Disease | Scleroderma;FunDO |
Disease | Muscular dystrophies;FunDO |
Disease | Lung cancer;FunDO |
Disease | Biliary Atresia;FunDO |
Disease | Osteosarcoma;FunDO |
Disease | Liver cancer;FunDO |
Disease | Stomach cancer;FunDO |
Disease | Breast cancer;FunDO |
Disease | Diabetes mellitus;FunDO |
Disease | Embryoma;FunDO |
Disease | Gallbaldder cancer;FunDO |
Disease | Chronic rejection of renal transplant;FunDO |
Disease | Systemic scleroderma;FunDO |
Disease | Liver disease;FunDO |
Disease | Pancreas cancer;FunDO |
Disease | Kidney disease;FunDO |
Disease | Drug abuse;FunDO |
Disease | Fibroid tumor;FunDO |
Disease | Proteinuria;FunDO |
Disease | Malaria;FunDO |
Disease | Brain tumor;FunDO |
Disease | Hypertension;FunDO |
Disease | Squamous cell cancer;FunDO |
Disease | Gouts;FunDO |
Disease | IGA glomerulonephritis;FunDO |
Disease | Metastasis to lymph nodes;FunDO |
Disease | Ovarian cancer;FunDO |
Disease | Congenital abnormality;FunDO |
|
External Links |
|
Links to Entrez Gene | 1490 |
Links to all GeneRIF Items | 1490 |
Links to iHOP | 1490 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>1490 : length: 1050 atgaccgccgccagtatgggccccgtccgcgtcgccttcgtggtcctcctcgccctctgc agccggccggccgtcggccagaactgcagcgggccgtgccggtgcccggacgagccggcg ccgcgctgcccggcgggcgtgagcctcgtgctggacggctgcggctgctgccgcgtctgc gccaagcagctgggcgagctgtgcaccgagcgcgacccctgcgacccgcacaagggcctc ttctgtgacttcggctccccggccaaccgcaagatcggcgtgtgcaccgccaaagatggt gctccctgcatcttcggtggtacggtgtaccgcagcggagagtccttccagagcagctgc aagtaccagtgcacgtgcctggacggggcggtgggctgcatgcccctgtgcagcatggac gttcgtctgcccagccctgactgccccttcccgaggagggtcaagctgcccgggaaatgc tgcgaggagtgggtgtgtgacgagcccaaggaccaaaccgtggttgggcctgccctcgcg gcttaccgactggaagacacgtttggcccagacccaactatgattagagccaactgcctg gtccagaccacagagtggagcgcctgttccaagacctgtgggatgggcatctccacccgg gttaccaatgacaacgcctcctgcaggctagagaagcagagccgcctgtgcatggtcagg ccttgcgaagctgacctggaagagaacattaagaagggcaaaaagtgcatccgtactccc aaaatctccaagcctatcaagtttgagctttctggctgcaccagcatgaagacataccga gctaaattctgtggagtatgtaccgacggccgatgctgcaccccccacagaaccaccacc ctgccggtggagttcaagtgccctgacggcgaggtcatgaagaagaacatgatgttcatc aagacctgtgcctgccattacaactgtcccggagacaatgacatctttgaatcgctgtac tacaggaagatgtacggagacatggcatga |
Protein Sequence |
>1490 : length: 349 MTAASMGPVRVAFVVLLALCSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVC AKQLGELCTERDPCDPHKGLFCDFGSPANRKIGVCTAKDGAPCIFGGTVYRSGESFQSSC KYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDQTVVGPALA AYRLEDTFGPDPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNASCRLEKQSRLCMVR PCEADLEENIKKGKKCIRTPKISKPIKFELSGCTSMKTYRAKFCGVCTDGRCCTPHRTTT LPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDIFESLYYRKMYGDMA |