| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 1601 |
Name | DAB2 |
Synonym | DOC-2|DOC2;Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila);DAB2;Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
Definition | adaptor molecule disabled-2|differentially expressed in ovarian carcinoma 2|differentially-expressed protein 2|disabled homolog 2|disabled homolog 2, mitogen-responsive phosphoprotein |
Position | 5p13.1 |
Gene Type | protein-coding |
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TSG scores |
Description |
| TUSON ranking | 5684 |
TUSON P-value | 1 |
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Pathways and Diseases |
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Pathway | Membrane Trafficking;Reactome;REACT:11123 |
Pathway | Endocytosis;KEGG PATHWAY;hsa04144 |
Pathway | TGF-beta receptor signaling;PID Curated;200195 |
Disease | Chronic kidney disease;NHGRI |
Disease | Cancer;FunDO |
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External Links |
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Links to Entrez Gene | 1601 |
Links to all GeneRIF Items | 1601 |
Links to iHOP | 1601 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>1601 : length: 2313 atgtctaacgaagtagaaacaagtgcaaccaatggtcagcccgaccaacaggccgcacca aaagcaccctcaaagaaggaaaaaaagaaaggccctgaaaagacagatgaatatctctta gcaaggttcaaaggcgatggtgtaaaatataaggccaagctgattggcattgatgatgtg ccagatgcaagaggggataaaatgagccaagactctatgatgaaactaaagggaatggcg gcagctggtcggtctcagggacaacacaaacaaaggatctgggtcaacatttccctttct gggataaaaataattgatgagaaaactggggtaatagagcatgaacatccagtaaataag atttctttcattgcccgtgatgtgacagacaaccgggcatttggttacgtgtgtggagga gaaggccagcatcagttttttgccataaaaaccgggcaacaggctgaaccattagttgtt gatcttaaagacctttttcaagttatctataatgtaaagaaaaaggaagaagaaaagaaa aagatagaggaagccagcaaagcagttgagaatgggagtgaggccctaatgattctagat gaccaaactaacaaactgaaatcgggtgttgaccagatggatttgtttggggacatgtct acacctcctgacctaaatagtccaacagaaagcaaagatatcctgttagtggatctaaac tctgaaatcgacaccaatcagaattctttaagagaaaatccattcttaacaaacggcatc acctcctgttctcttcctcgaccaacgcctcaggcatccttcttgcctgaaaatgccttt tctgccaatctcaacttctttcccacccctaatcctgatcctttccgtgacgatcctttc acacagccagaccaatcgacaccttcttcgtttgattctctcaaatctccagatcagaag aaagagaattcgagtagctcgtctactccgctgagtaatgggcccctgaatggtgatgtt gactactttggtcagcaatttgaccagatctctaaccggactggcaaacaggaagctcag gcaggcccatggcccttttcaagttcgcaaacccagccagcagtgagaactcaaaatggg gtatctgaaagagaacagaacggcttctctgtcaaatcctccccgaacccttttgtggga agccctcccaaaggactgtccatacagaatggcgtaaagcaggacttggaaagctctgtc cagtcctcaccacatgactccatagccattatcccacctccacaaagtaccaaaccagga agaggcagaaggactgctaagtcttcagccaatgacttgcttgcatcagacatctttgct cctcccgtctcagaaccttcaggccaggcgtcacccacaggacaacctacagccctgcag cccaaccctctggatctcttcaaaacaagtgctcctgccccagtggggcccctggtgggt ctaggtggtgtaactgtcacactccctcaggcaggaccatggaacacagcatctttggtc ttcaatcagtccccttcaatggctccgggagccatgatgggtggtcaaccttcaggtttt agtcagcccgtcatttttggtacaagtccagctgtttcaggttggaaccagccttcaccc tttgcagcctcaactccccctccagtgcctgttgtctggggcccttctgcatctgtggca cccaatgcttggtcaacaacaagccctttggggaatccttttcagagcaatatttttcca gctcctgctgtgtccactcagcccccatccatgcactcctctctcctggtcactcctcct cagccacctcccagagctggccctcccaaggacatctccagtgatgccttcactgcctta gacccacttggggataaagagatcaaggatgtgaaagaaatgtttaaggatttccaactg cggcagccacctgctgtgcccgcgcggaagggagagcagacttcttctgggactttgagt gcctttgccagttatttcaacagcaaggttggcattcctcaggagaatgcagaccatgat gactttgatgctaatcaactattgaacaagatcaatgaaccaccaaagccagctcccaga caagtttccctgccagttaccaaatctactgacaatgcatttgagaaccctttctttaaa gattcttttggttcatcacaagcctctgtggcttcttctcaacctgtatcttctgagatg tatagggatccatttggaaatccttttgcctaa |
Protein Sequence |
>1601 : length: 770 MSNEVETSATNGQPDQQAAPKAPSKKEKKKGPEKTDEYLLARFKGDGVKYKAKLIGIDDV PDARGDKMSQDSMMKLKGMAAAGRSQGQHKQRIWVNISLSGIKIIDEKTGVIEHEHPVNK ISFIARDVTDNRAFGYVCGGEGQHQFFAIKTGQQAEPLVVDLKDLFQVIYNVKKKEEEKK KIEEASKAVENGSEALMILDDQTNKLKSGVDQMDLFGDMSTPPDLNSPTESKDILLVDLN SEIDTNQNSLRENPFLTNGITSCSLPRPTPQASFLPENAFSANLNFFPTPNPDPFRDDPF TQPDQSTPSSFDSLKSPDQKKENSSSSSTPLSNGPLNGDVDYFGQQFDQISNRTGKQEAQ AGPWPFSSSQTQPAVRTQNGVSEREQNGFSVKSSPNPFVGSPPKGLSIQNGVKQDLESSV QSSPHDSIAIIPPPQSTKPGRGRRTAKSSANDLLASDIFAPPVSEPSGQASPTGQPTALQ PNPLDLFKTSAPAPVGPLVGLGGVTVTLPQAGPWNTASLVFNQSPSMAPGAMMGGQPSGF SQPVIFGTSPAVSGWNQPSPFAASTPPPVPVVWGPSASVAPNAWSTTSPLGNPFQSNIFP APAVSTQPPSMHSSLLVTPPQPPPRAGPPKDISSDAFTALDPLGDKEIKDVKEMFKDFQL RQPPAVPARKGEQTSSGTLSAFASYFNSKVGIPQENADHDDFDANQLLNKINEPPKPAPR QVSLPVTKSTDNAFENPFFKDSFGSSQASVASSQPVSSEMYRDPFGNPFA |