| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 1612 |
Name | DAPK1 |
Synonym | DAPK;death-associated protein kinase 1;DAPK1;death-associated protein kinase 1 |
Definition | DAP kinase 1 |
Position | 9q21.33 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 5699 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Apoptosis;Reactome;REACT:578 |
Pathway | Role of DCC in regulating apoptosis;PID Reactome;500280 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | IFN-gamma pathway;PID Curated;200110 |
Pathway | Bladder cancer;KEGG PATHWAY;hsa05219 |
Pathway | Netrin-mediated signaling;PID Curated;200074 |
Disease | Cancers;KEGG DISEASE |
Disease | smoking cessation;GAD |
Disease | CHEMDEPENDENCY;GAD |
Disease | Cancers of the urinary system and male genital organs;KEGG DISEASE |
Disease | Gastritis;FunDO |
Disease | Cancer;FunDO |
Disease | Bladder cancer;KEGG DISEASE;H00022 |
Disease | Epilepsy;FunDO |
Disease | Alzheimer's disease;GAD |
Disease | NEUROLOGICAL;GAD |
Disease | Bronchial disease;FunDO |
|
External Links |
|
Links to Entrez Gene | 1612 |
Links to all GeneRIF Items | 1612 |
Links to iHOP | 1612 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>1612 : length: 4293 atgaccgtgttcaggcaggaaaacgtggatgattactacgacaccggcgaggaacttggc agtggacagtttgcggttgtgaagaaatgccgtgagaaaagcaccggcctccagtatgcc gccaaattcatcaagaaaaggaggactaagtccagccggcggggtgtgagccgcgaggac atcgagcgggaggtcagcatcctgaaggagatccagcaccccaatgtcatcaccctgcac gaggtctatgagaacaagacggacgtcatcctgatcttggaactcgttgcaggtggcgag ctgtttgacttcttagctgaaaaggaatctttaactgaagaggaagcaactgaatttctc aaacaaattcttaatggtgtttactacctgcactcccttcaaatcgcccactttgatctt aagcctgagaacataatgcttttggatagaaatgtccccaaacctcggatcaagatcatt gactttgggttggcccataaaattgactttggaaatgaatttaaaaacatatttgggact ccagagtttgtcgctcctgagatagtcaactatgaacctcttggtcttgaggcagatatg tggagtatcggggtaataacctatatcctcctaagtggggcctccccatttcttggagac actaagcaagaaacgttagcaaatgtatccgctgtcaactacgaatttgaggatgaatac ttcagtaataccagtgccctagccaaagatttcataagaagacttctggtcaaggatcca aagaagagaatgacaattcaagatagtttgcagcatccctggatcaagcctaaagataca caacaggcacttagtagaaaagcatcagcagtaaacatggagaaattcaagaagtttgca gcccggaaaaaatggaaacaatccgttcgcttgatatcactgtgccaaagattatccagg tcattcctgtccagaagtaacatgagtgttgccagaagcgatgatactctggatgaggaa gactcctttgtgatgaaagccatcatccatgccatcaacgatgacaatgtcccaggcctg cagcaccttctgggctcattatccaactatgatgttaaccaacccaacaagcacgggaca cctccattactcattgctgctggctgtgggaatattcaaatactacagttgctcattaaa agaggctcgagaatcgatgtccaggataagggcgggtccaatgccgtctactgggctgct cggcatggccacgtcgataccttgaaatttctcagtgagaacaaatgccctttggatgtg aaagacaagtctggagagatggccctccacgtggcagctcgctatggccatgctgacgtg gctcagttactgtgcagcttcggctcaaatcccaatatccaggacaaggaagaagaaacc cccctgcactgtgctgcttggcacggctattactctgtggccaaagccctttgtgaagcc ggctgtaacgtgaacatcaagaaccgagaaggagagacgcccctcctgacagcctctgcc aggggctaccacgacatcgtggagtgtctggccgaacatggagccgaccttaatgcttgc gacaaggacggacacattgcccttcatctggctgtaagacggtgtcagatggaggtaatc aagactctcctcagccaagggtgtttcgtcgattatcaagacaggcacggcaatactccc ctccatgtggcatgtaaagatggcaacatgcctatcgtggtggccctctgtgaagcaaac tgcaatttggacatctccaacaagtatgggcgaacgcctctgcaccttgcggccaacaac ggaatcctagacgtggtccggtatctctgtctgatgggagccagcgttgaggcgctgacc acggacggaaagacggcagaagatcttgctagatcggaacagcacgagcacgtagcaggt ctccttgcaagacttcgaaaggatacgcaccgaggactcttcatccagcagctccgaccc acacagaacctgcagccaagaattaagctcaagctgtttggccactcgggatccgggaaa accacccttgtagaatctctcaagtgtgggctgctgaggagctttttcagaaggcgtcgg cccagactgtcttccaccaactccagcaggttcccaccttcacccctggcttctaagccc acagtctcagtgagcatcaacaacctgtacccaggctgcgagaacgtgagtgtgaggagc cgcagcatgatgttcgagccgggtcttaccaaagggatgctggaggtgtttgtggccccg acccaccacccgcactgctcggccgatgaccagtccaccaaggccatcgacatccagaac gcttatttgaatggagttggcgatttcagcgtgtgggagttctctggaaatcctgtgtat ttctgctgttatgactattttgctgcaaatgatcccacgtcaatccatgttgttgtcttt agtctagaagagccctatgagatccagctgaaccaagtgattttctggctcagtttcctg aagtcccttgtcccagttgaagaacccatagccttcggtggcaagctgaagaacccactc caagttgtcctggtggccacccacgctgacatcatgaatgttcctcgaccggctggaggc gagtttggatatgacaaagacacatcgttgctgaaagagattaggaacaggtttggaaat gatcttcacatttcaaataagctgtttgttctggatgctggggcttctgggtcaaaggac atgaaggtacttcgaaatcatctgcaagaaatacgaagccagattgtttcggtctgtcct cccatgactcacctgtgtgagaaaatcatctccacgctgccttcctggaggaagctcaat ggacccaaccagctgatgtcgctgcagcagtttgtgtacgacgtgcaggaccagctgaac cccctggccagcgaggaggacctcaggcgcattgctcagcagctccacagcacaggcgag atcaacatcatgcaaagtgaaacagttcaggacgtgctgctcctggacccccgctggctc tgcacaaacgtcctggggaagttgctgtccgtggagaccccacgggcgctgcaccactac cggggccgctacaccgtggaggacatccagcgcctggtgcccgacagcgacgtggaggag ctgctgcagatcctcgatgccatggacatctgcgcccgggacctgagcagcgggaccatg gtggacgtcccagccctgatcaagacagacaacctgcaccgctcctgggctgatgaggag gacgaggtgatggtgtatggtggcgtgcgcatcgtgcccgtggaacacctcacccccttc ccatgtggcatctttcacaaggtccaggtgaacctgtgccggtggatccaccagcaaagc acagagggcgacgcggacatccgcctgtgggtgaatggctgcaagctggccaaccgtggg gccgagctgctggtgctgctggtcaaccacggccagggcattgaggtccaggtccgcggc ctggagacggagaagatcaagtgctgcctgctgctggactcggtgtgcagcaccattgag aacgtcatggccaccacgctgccagggctcctgaccgtgaagcattacctgagcccccag cagctgcgggagcaccatgagcccgtcatgatctaccagccacgggacttcttccgggca cagactctgaaggaaacctcactgaccaacaccatgggggggtacaaggaaagcttcagc agcatcatgtgcttcgggtgtcacgacgtctactcacaggccagcctcggcatggacatc catgcatcagacctgaacctcctcactcggaggaaactgagtcgcctgctggacccgccc gaccccctggggaaggactggtgccttctcgccatgaacttaggcctccctgacctcgtg gcaaagtacaacaccagtaacggggctcccaaggatttcctccccagccccctccacgcc ctgctgcgggaatggaccacctaccctgagagcacagtgggcaccctcatgtccaaactg agggagctgggtcgccgggatgccgcagactttttgctgaaggcatcctctgtgttcaaa atcaacctggatggcaatggccaggaggcctatgcctcgagctgcaacagcggcacctct tacaattccattagctctgttgtatcccggtga |
Protein Sequence |
>1612 : length: 1430 MTVFRQENVDDYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSRED IEREVSILKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFL KQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGT PEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEY FSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQALSRKASAVNMEKFKKFA ARKKWKQSVRLISLCQRLSRSFLSRSNMSVARSDDTLDEEDSFVMKAIIHAINDDNVPGL QHLLGSLSNYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAA RHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEET PLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNAC DKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEAN CNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKTAEDLARSEQHEHVAG LLARLRKDTHRGLFIQQLRPTQNLQPRIKLKLFGHSGSGKTTLVESLKCGLLRSFFRRRR PRLSSTNSSRFPPSPLASKPTVSVSINNLYPGCENVSVRSRSMMFEPGLTKGMLEVFVAP THHPHCSADDQSTKAIDIQNAYLNGVGDFSVWEFSGNPVYFCCYDYFAANDPTSIHVVVF SLEEPYEIQLNQVIFWLSFLKSLVPVEEPIAFGGKLKNPLQVVLVATHADIMNVPRPAGG EFGYDKDTSLLKEIRNRFGNDLHISNKLFVLDAGASGSKDMKVLRNHLQEIRSQIVSVCP PMTHLCEKIISTLPSWRKLNGPNQLMSLQQFVYDVQDQLNPLASEEDLRRIAQQLHSTGE INIMQSETVQDVLLLDPRWLCTNVLGKLLSVETPRALHHYRGRYTVEDIQRLVPDSDVEE LLQILDAMDICARDLSSGTMVDVPALIKTDNLHRSWADEEDEVMVYGGVRIVPVEHLTPF PCGIFHKVQVNLCRWIHQQSTEGDADIRLWVNGCKLANRGAELLVLLVNHGQGIEVQVRG LETEKIKCCLLLDSVCSTIENVMATTLPGLLTVKHYLSPQQLREHHEPVMIYQPRDFFRA QTLKETSLTNTMGGYKESFSSIMCFGCHDVYSQASLGMDIHASDLNLLTRRKLSRLLDPP DPLGKDWCLLAMNLGLPDLVAKYNTSNGAPKDFLPSPLHALLREWTTYPESTVGTLMSKL RELGRRDAADFLLKASSVFKINLDGNGQEAYASSCNSGTSYNSISSVVSR |