| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 1676 |
Name | DFFA |
Synonym | DFF-45|DFF1|ICAD;DNA fragmentation factor, 45kDa, alpha polypeptide;DFFA;DNA fragmentation factor, 45kDa, alpha polypeptide |
Definition | DFF45|DNA fragmentation factor 45 kDa subunit|DNA fragmentation factor subunit alpha|inhibitor of CAD |
Position | 1p36.3-p36.2 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 5894 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Apoptosis;Reactome;REACT:578 |
Pathway | Activation of DNA fragmentation factor;PID Reactome;500275 |
Pathway | Apoptosis;KEGG PATHWAY;hsa04210 |
Pathway | Caspase cascade in apoptosis;PID Curated;200148 |
Pathway | hiv-1 nef: negative effector of fas and tnf;PID BioCarta;100144 |
Pathway | induction of apoptosis through dr3 and dr4/5 death receptors;PID BioCarta;100189 |
Pathway | HIV-1 Nef: Negative effector of Fas and TNF-alpha;PID Curated;200133 |
Pathway | caspase cascade in apoptosis;PID BioCarta;100218 |
Pathway | apoptotic dna-fragmentation and tissue homeostasis;PID BioCarta;100187 |
Pathway | granzyme a mediated apoptosis pathway;PID BioCarta;100035 |
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External Links |
|
Links to Entrez Gene | 1676 |
Links to all GeneRIF Items | 1676 |
Links to iHOP | 1676 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>1676 : length: 996 atggaggtgaccggggacgccggggtaccagaatctggcgagatccggactctaaagccg tgtctgctgcgccgcaactacagccgcgaacagcacggcgtggccgcctcctgcctcgaa gacctgaggagcaaggcctgtgacattctggccattgataagtccctgacaccagtcacc ctggtcctggcagaggatggcaccatagtggatgatgacgattactttctgtgtctacct tccaatactaagtttgtggcattggctagtaatgagaaatgggcatacaacaattcagat ggaggtacagcttggatttcccaagagtcctttgatgtagatgaaacagacagcggggca gggttgaagtggaagaatgtggccaggcagctgaaagaagatctgtccagcatcatcctc ctatcagaggaggacctccagatgcttgttgacgctccctgctcagacctggctcaggaa ctacgtcagagttgtgccaccgtccagcggctgcagcacacactccaacaggtgcttgac caaagagaggaagtgcgtcagtccaagcagctcctgcagctgtacctccaggctttggag aaagagggcagcctcttgtcaaagcaggaagagtccaaagctgcctttggtgaggaggtg gatgcagtagacacgggtatcagcagagagacctcctcggacgttgcgctggcgagccac atccttactgcactgagggagaagcaggctccagagctgagcttatctagtcaggatttg gagttggttaccaaggaagaccccaaagcactggctgttgccttgaactgggacataaag aagacggagactgttcaggaggcctgtgagcgggagctcgccctgcgcctgcagcagacg cagagcttgcattctctccggagcatctcagcaagcaaggcctcaccacctggtgacctg cagaatcctaagcgagccagacaggatcccacatag |
Protein Sequence |
>1676 : length: 331 MEVTGDAGVPESGEIRTLKPCLLRRNYSREQHGVAASCLEDLRSKACDILAIDKSLTPVT LVLAEDGTIVDDDDYFLCLPSNTKFVALASNEKWAYNNSDGGTAWISQESFDVDETDSGA GLKWKNVARQLKEDLSSIILLSEEDLQMLVDAPCSDLAQELRQSCATVQRLQHTLQQVLD QREEVRQSKQLLQLYLQALEKEGSLLSKQEESKAAFGEEVDAVDTGISRETSSDVALASH ILTALREKQAPELSLSSQDLELVTKEDPKALAVALNWDIKKTETVQEACERELALRLQQT QSLHSLRSISASKASPPGDLQNPKRARQDPT |