| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 1786 |
Name | DNMT1 |
Synonym | ADCADN|AIM|CXXC9|DNMT|HSN1E|MCMT;DNA (cytosine-5-)-methyltransferase 1;DNMT1;DNA (cytosine-5-)-methyltransferase 1 |
Definition | CXXC-type zinc finger protein 9|DNA (cytosine-5)-methyltransferase 1|DNA MTase HsaI|DNA methyltransferase HsaI|m.HsaI |
Position | 19p13.2 |
Gene Type | protein-coding |
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TSG scores |
Description |
| TUSON ranking | 6099 |
TUSON P-value | 1 |
| Caution | This gene might be oncogene according to our integrated oncogene list. |
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Pathways and Diseases |
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Pathway | Regulation of retinoblastoma protein;PID Curated;200191 |
Pathway | Cysteine and methionine metabolism;KEGG PATHWAY;hsa00270 |
Pathway | Metabolic pathways;KEGG PATHWAY;hsa01100 |
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External Links |
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Links to Entrez Gene | 1786 |
Links to all GeneRIF Items | 1786 |
Links to iHOP | 1786 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>1786 : length: 4899 atgccggcgcgtaccgccccagcccgggtgcccacactggccgtcccggccatctcgctg cccgacgatgtccgcaggcggctcaaagatttggaaagagacagcttaacagaaaaggaa tgtgtgaaggagaaattgaatctcttgcacgaatttctgcaaacagaaataaagaatcag ttatgtgacttggaaaccaaattacgtaaagaagaattatccgaggagggctacctggct aaagtcaaatcccttttaaataaagatttgtccttggagaacggtgctcatgcttacaac cgggaagtgaatggacgtctagaaaacgggaaccaagcaagaagtgaagcccgtagagtg ggaatggcagatgccaacagcccccccaaacccctttccaaacctcgcacgcccaggagg agcaagtccgatggagaggctaagcgttcaagagaccctcctgcctcagcctcccaagta actgggattagagctgaaccttcacctagccccaggattacaaggaaaagcaccaggcaa accaccatcacatctcattttgcaaagggccctgccaaacggaaacctcaggaagagtct gaaagagccaaatcggatgagtccatcaaggaagaagacaaagaccaggatgagaagaga cgtagagttacatccagagaacgagttgctagaccgcttcctgcagaagaacctgaaaga gcaaaatcaggaacgcgcactgaaaaggaagaagaaagagatgaaaaagaagaaaagaga ctccgaagtcaaaccaaagaaccaacacccaaacagaaactgaaggaggagccggacaga gaagccagggcaggcgtgcaggctgacgaggacgaagatggagacgagaaagatgagaag aagcacagaagtcaacccaaagatctagctgccaaacggaggcccgaagaaaaagaacct gaaaaagtaaatccacagatttctgatgaaaaagacgaggatgaaaaggaggagaagaga cgcaaaacgacccccaaagaaccaacggagaaaaaaatggctcgcgccaaaacagtcatg aactccaagacccaccctcccaagtgcattcagtgcgggcagtacctggacgaccctgac ctcaaatatgggcagcacccaccagacgcggtggatgagccacagatgctgacaaatgag aagctgtccatctttgatgccaacgagtctggctttgagagttatgaggcgcttccccag cacaaactgacctgcttcagtgtgtactgtaagcacggtcacctgtgtcccatcgacacc ggcctcatcgagaagaatatcgaactcttcttttctggttcagcaaaaccaatctatgat gatgacccatctcttgaaggtggtgttaatggcaaaaatcttggccccataaatgaatgg tggatcactggctttgatggaggtgaaaaggccctcatcggcttcagcacctcatttgcc gaatacattctgatggatcccagtcccgagtatgcgcccatatttgggctgatgcaggag aagatctacatcagcaagattgtggtggagttcctgcagagcaattccgactcgacctat gaggacctgatcaacaagatcgagaccacggttcctccttctggcctcaacttgaaccgc ttcacagaggactccctcctgcgacacgcgcagtttgtggtggagcaggtggagagttat gacgaggccggggacagtgatgagcagcccatcttcctgacaccctgcatgcgggacctg atcaagctggctggggtcacgctgggacagaggcgagcccaggcgaggcggcagaccatc aggcattctaccagggagaaggacaggggacccacgaaagccaccaccaccaagctggtc taccagatcttcgatactttcttcgcagagcaaattgaaaaggatgacagagaagacaag gagaacgcctttaagcgccggcgatgtggcgtctgtgaggtgtgtcagcagcctgagtgt gggaaatgtaaagcctgcaaggacatggttaaatttggtggcagtggacggagcaagcag gcttgccaagagcggaggtgtcccaatatggccatgaaggaggcagatgacgatgaggaa gtcgatgataacatcccagagatgccgtcacccaaaaaaatgcaccaggggaagaagaag aaacagaacaagaatcgcatctcttgggtcggagaagccgtcaagactgatgggaagaag agttactataagaaggtgtgcattgatgcggaaaccctggaagtgggggactgtgtctct gttattccagatgattcctcaaaaccgctgtatctagcaagggtcacggcgctgtgggag gacagcagcaacgggcagatgtttcacgcccactggttctgcgctgggacagacacagtc ctcggggccacgtcggaccctctggagctgttcttggtggatgaatgtgaggacatgcag ctttcatatatccacagcaaagtgaaagtcatctacaaagccccctccgaaaactgggcc atggagggaggcatggatcccgagtccctgctggagggggacgacgggaagacctacttc taccagctgtggtatgatcaagactacgcgagattcgagtcccctccaaaaacccagcca acagaggacaacaagttcaaattctgtgtgagctgtgcccgtctggctgagatgaggcaa aaagaaatccccagggtcctggagcagctcgaggacctggatagccgggtcctctactac tcagccaccaagaacggcatcctgtaccgagttggtgatggtgtgtacctgccccctgag gccttcacgttcaacatcaagctgtccagtcccgtgaaacgcccacggaaggagcccgtg gatgaggacctgtacccagagcactaccggaaatactccgactacatcaaaggcagcaac ctggatgcccctgagccctaccgaattggccggatcaaagagatcttctgtcccaagaag agcaacggcaggcccaatgagactgacatcaaaatccgggtcaacaagttctacaggcct gagaacacccacaagtccactccagcgagctaccacgcagacatcaacctgctctactgg agcgacgaggaggccgtggtggacttcaaggctgtgcagggccgctgcaccgtggagtat ggggaggacctgcccgagtgcgtccaggtgtactccatgggcggccccaaccgcttctac ttcctcgaggcctataatgcaaagagcaaaagctttgaagatcctcccaaccatgcccgt agccctggaaacaaagggaagggcaagggaaaagggaagggcaagcccaagtcccaagcc tgtgagccgagcgagccagagatagagatcaagctgcccaagctgcggaccctggatgtg ttttctggctgcggggggttgtcggagggattccaccaagcaggcatctctgacacgctg tgggccatcgagatgtgggaccctgcggcccaggcgttccggctgaacaaccccggctcc acagtgttcacagaggactgcaacatcctgctgaagctggtcatggctggggagaccacc aactcccgcggccagcggctgccccagaagggagacgtggagatgctgtgcggcgggccg ccctgccagggcttcagcggcatgaaccgcttcaattcgcgcacctactccaagttcaaa aactctctggtggtttccttcctcagctactgcgactactaccggccccggttcttcctc ctggagaatgtcaggaactttgtctccttcaagcgctccatggtcctgaagctcaccctc cgctgcctggtccgcatgggctatcagtgcaccttcggcgtgctgcaggccggtcagtac ggcgtggcccagactaggaggcgggccatcatcctggccgcggcccctggagagaagctc cctctgttcccggagccactgcacgtgtttgctccccgggcctgccagctgagcgtggtg gtggatgacaagaagtttgtgagcaacataaccaggttgagctcgggtcctttccggacc atcacggtgcgagacacgatgtccgacctgccggaggtgcggaatggagcctcggcactg gagatctcctacaacggggagcctcagtcctggttccagaggcagctccggggcgcacag taccagcccatcctcagggaccacatctgtaaggacatgagtgcattggtggctgcccgc atgcggcacatccccttggccccagggtcagactggcgcgatctgcccaacatcgaggtg cggctctcagacggcaccatggccaggaagctgcggtatacccaccatgacaggaagaac ggccgcagcagctctggggccctccgtggggtctgctcctgcgtggaagccggcaaagcc tgcgaccccgcagccaggcagttcaacaccctcatcccctggtgcctgccccacaccggg aaccggcacaaccactgggctggcctctatggaaggctcgagtgggacggcttcttcagc acaaccgtcaccaaccccgagcccatgggcaagcagggccgcgtgctccacccagagcag caccgtgtggtgagcgtgcgggagtgtgcccgctcccagggcttccctgacacctaccgg ctcttcggcaacatcctggacaagcaccggcaggtgggcaatgccgtgccaccgcccctg gccaaagccattggcttggagatcaagctttgtatgttggccaaagcccgagagagtgcc tcagctaaaataaaggaggaggaagctgctaaggactag |
Protein Sequence |
>1786 : length: 1632 MPARTAPARVPTLAVPAISLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQ LCDLETKLRKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRV GMADANSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQ TTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPER AKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEK KHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVM NSKTHPPKCIQCGQYLDDPDLKYGQHPPDAVDEPQMLTNEKLSIFDANESGFESYEALPQ HKLTCFSVYCKHGHLCPIDTGLIEKNIELFFSGSAKPIYDDDPSLEGGVNGKNLGPINEW WITGFDGGEKALIGFSTSFAEYILMDPSPEYAPIFGLMQEKIYISKIVVEFLQSNSDSTY EDLINKIETTVPPSGLNLNRFTEDSLLRHAQFVVEQVESYDEAGDSDEQPIFLTPCMRDL IKLAGVTLGQRRAQARRQTIRHSTREKDRGPTKATTTKLVYQIFDTFFAEQIEKDDREDK ENAFKRRRCGVCEVCQQPECGKCKACKDMVKFGGSGRSKQACQERRCPNMAMKEADDDEE VDDNIPEMPSPKKMHQGKKKKQNKNRISWVGEAVKTDGKKSYYKKVCIDAETLEVGDCVS VIPDDSSKPLYLARVTALWEDSSNGQMFHAHWFCAGTDTVLGATSDPLELFLVDECEDMQ LSYIHSKVKVIYKAPSENWAMEGGMDPESLLEGDDGKTYFYQLWYDQDYARFESPPKTQP TEDNKFKFCVSCARLAEMRQKEIPRVLEQLEDLDSRVLYYSATKNGILYRVGDGVYLPPE AFTFNIKLSSPVKRPRKEPVDEDLYPEHYRKYSDYIKGSNLDAPEPYRIGRIKEIFCPKK SNGRPNETDIKIRVNKFYRPENTHKSTPASYHADINLLYWSDEEAVVDFKAVQGRCTVEY GEDLPECVQVYSMGGPNRFYFLEAYNAKSKSFEDPPNHARSPGNKGKGKGKGKGKPKSQA CEPSEPEIEIKLPKLRTLDVFSGCGGLSEGFHQAGISDTLWAIEMWDPAAQAFRLNNPGS TVFTEDCNILLKLVMAGETTNSRGQRLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFK NSLVVSFLSYCDYYRPRFFLLENVRNFVSFKRSMVLKLTLRCLVRMGYQCTFGVLQAGQY GVAQTRRRAIILAAAPGEKLPLFPEPLHVFAPRACQLSVVVDDKKFVSNITRLSSGPFRT ITVRDTMSDLPEVRNGASALEISYNGEPQSWFQRQLRGAQYQPILRDHICKDMSALVAAR MRHIPLAPGSDWRDLPNIEVRLSDGTMARKLRYTHHDRKNGRSSSGALRGVCSCVEAGKA CDPAARQFNTLIPWCLPHTGNRHNHWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQ HRVVSVRECARSQGFPDTYRLFGNILDKHRQVGNAVPPPLAKAIGLEIKLCMLAKARESA SAKIKEEEAAKD |