| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 185 |
Name | AGTR1 |
Synonym | AG2S|AGTR1B|AT1|AT1AR|AT1B|AT1BR|AT1R|AT2R1|HAT1R;angiotensin II receptor, type 1;AGTR1;angiotensin II receptor, type 1 |
Definition | type-1 angiotensin II receptor|type-1B angiotensin II receptor |
Position | 3q24 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 2553 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Vascular smooth muscle contraction;KEGG PATHWAY;hsa04270 |
Pathway | Angiopoietin receptor Tie2-mediated signaling;PID Curated;200066 |
Pathway | Calcium signaling pathway;KEGG PATHWAY;hsa04020 |
Pathway | Signaling by GPCR;Reactome;REACT:14797 |
Pathway | Neuroactive ligand-receptor interaction;KEGG PATHWAY;hsa04080 |
Pathway | Arf6 signaling events;PID Curated;200060 |
Pathway | Renin-angiotensin system;KEGG PATHWAY;hsa04614 |
Pathway | angiotensin ii mediated activation of jnk pathway via pyk2 dependent signaling;PID BioCarta;100236 |
Disease | Ischemia;FunDO |
Disease | Adenocarcinoma;FunDO |
Disease | IMMUNE;GAD |
Disease | deep venous thrombosis;GAD |
Disease | Premature birth;FunDO |
Disease | Hypertension, Pulmonary;GAD |
Disease | Cardiovascular disease;FunDO |
Disease | Brain ischemia;FunDO |
Disease | cardiovascular;GAD |
Disease | cardiac death;GAD |
Disease | Connective Tissue Diseases;GAD |
Disease | Hypertension, essential;OMIM |
Disease | Breast cancer;FunDO |
Disease | Stomach cancer;FunDO |
Disease | Depression;FunDO |
Disease | Essential Hypertension;GAD |
Disease | Esotropia;FunDO |
Disease | Hypercholesterolemia;FunDO |
Disease | Embryoma;FunDO |
Disease | Mucocutaneous lymph node syndrome;FunDO |
Disease | hypertension;GAD |
Disease | hypercholesterolemia;GAD |
Disease | cardiac morbidity;GAD |
Disease | atherosclerosis, coronary;GAD |
Disease | kidney transplant;GAD |
Disease | Systemic scleroderma;FunDO |
Disease | Rheumatoid arthritis;FunDO |
Disease | Renal tubular dysgenesis;OMIM |
Disease | PHARMACOGENOMIC;GAD |
Disease | METABOLIC;GAD |
Disease | anthropometric and metabolic traits, relative to cardiovascular risk;GAD |
Disease | Coronary Artery Disease;GAD |
Disease | Lupus erythematosus;FunDO |
Disease | Kidney disease;FunDO |
Disease | Heart Failure;GAD |
Disease | diabetes, type 2;GAD |
Disease | Hamman-Rich syndrome;FunDO |
Disease | Diabetes mellitus;FunDO |
Disease | Adenoma;FunDO |
Disease | increased vascular reactivity;GAD |
Disease | coronary artery vasoconstriction.;GAD |
Disease | CARDIOVASCULAR;GAD |
Disease | Stroke;GAD |
Disease | Hyperaldosteronism;FunDO |
Disease | Adrenal gland tumor;FunDO |
Disease | hypertension, pregnancy induced;GAD |
Disease | Hypertension;FunDO |
Disease | nephropathy, diabetic;GAD |
Disease | IGA glomerulonephritis;FunDO |
Disease | heart rate;GAD |
Disease | Abortion;FunDO |
Disease | atherosclerosis, coronary endothelial function hypercholesterolemia lipids;GAD |
Disease | Lupus vulgaris;FunDO |
Disease | Ovarian cancer;FunDO |
Disease | Heart disease;FunDO |
Disease | Obesity;FunDO |
Disease | Myocardial Infarction;GAD |
Disease | Atherosclerosis;FunDO |
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External Links |
|
Links to Entrez Gene | 185 |
Links to all GeneRIF Items | 185 |
Links to iHOP | 185 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>185 : length: 1080 atgattctcaactcttctactgaagatggtattaaaagaatccaagatgattgtcccaaa gctggaaggcataattacatatttgtcatgattcctactttatacagtatcatctttgtg gtgggaatatttggaaacagcttggtggtgatagtcatttacttttatatgaagctgaag actgtggccagtgtttttcttttgaatttagcactggctgacttatgctttttactgact ttgccactatgggctgtctacacagctatggaataccgctggccctttggcaattaccta tgtaagattgcttcagccagcgtcagtttcaacctgtacgctagtgtgtttctactcacg tgtctcagcattgatcgatacctggctattgttcacccaatgaagtcccgccttcgacgc acaatgcttgtagccaaagtcacctgcatcatcatttggctgctggcaggcttggccagt ttgccagctataatccatcgaaatgtatttttcattgagaacaccaatattacagtttgt gctttccattatgagtcccaaaattcaaccctcccgatagggctgggcctgaccaaaaat atactgggtttcctgtttccttttctgatcattcttacaagttatactcttatttggaag gccctaaagaaggcttatgaaattcagaagaacaaaccaagaaatgatgatatttttaag ataattatggcaattgtgcttttctttttcttttcctggattccccaccaaatattcact tttctggatgtattgattcaactaggcatcatacgtgactgtagaattgcagatattgtg gacacggccatgcctatcaccatttgtatagcttattttaacaattgcctgaatcctctt ttttatggctttctggggaaaaaatttaaaagatattttctccagcttctaaaatatatt cccccaaaagccaaatcccactcaaacctttcaacaaaaatgagcacgctttcctaccgc ccctcagataatgtaagctcatccaccaagaagcctgcaccatgttttgaggttgagtga |
Protein Sequence |
>185 : length: 359 MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVC AFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFK IIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLNPL FYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAPCFEVE |