| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 185 |
Name | AGTR1 |
Synonymous | AG2S|AGTR1B|AT1|AT1AR|AT1B|AT1BR|AT1R|AT2R1|HAT1R;angiotensin II receptor, type 1;AGTR1;angiotensin II receptor, type 1 |
Definition | type-1 angiotensin II receptor|type-1B angiotensin II receptor |
Position | 3q24 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
 |
Transcription Factors [Top] |
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Regulation From TransFac database |
AT1A(h) --> STAT5(h) (phosphorylation) | AT1A(h) --> protein remnants (degradation) | AT1A(h) + n ubiquitin(h) --> AT1A(h){ub}n (ubiquitination) | AT1A(h) + DRD5(h) <==> AT1A(h):DRD5(h) (binding) | angiotensin II(h) --> AT1A(h) (activation) | AGTR1(h) --> AT1A(h) (expression). | AT1A(h) + beta-adaptin 2(h) <==> beta-adaptin 2(h):AT1A(h) (binding) | AT1A(h) + CHC(h) <==> AT1A(h):CHC(h) (binding) | AT1A(h) + ATRAP-isoform1(h) <==> AT1A(h):ATRAP-isoform1(h) (binding) | AT1A(h) + NDP-Gly --> AT1A(h){gly} + NMP (glycosylation) | AT1A(h) --> protein remnants (degradation) | AT1A(h) + n ubiquitin(h) --> AT1A(h){ub}n (ubiquitination) | angiotensin II(m.s.) + AT1A(h) <==> angiotensin II(m.s.):AT1A(h) (binding) | AGTR1(h) --> AT1A(h) (expression). | AGTR1(h) --> AGTR1(h) (expression). | hsa-miR-155 --/ AGTR1(h) (translational repression). |
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Post Transcriptional Modification [Top] | |||
|
Location (AA) |
PTM type |
Literature |
Database |
4 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 176 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 188 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 355 | S-palmitoyl cysteine (Potential). | Swiss-Prot 53.0 | 319 | Phosphotyrosine | 12522132 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr3 |
Promoter: 149896848 - 149898848 | Agilent_014791 |
chr3 |
Promoter: 149896848 - 149898848 | GoldenGate_Methylation_Cancer_Panel_I |
chr3 |
Promoter: 149896848 - 149898848 | GoldenGate_Methylation_Cancer_Panel_I |
chr3 |
Promoter: 149896848 - 149898848 | GoldenGate_Methylation_Cancer_Panel_I |
chr3 |
Promoter: 149896848 - 149898848 | GoldenGate_Methylation_Cancer_Panel_I |
chr3 |
Promoter: 149896848 - 149898848 | GSE27584 |
chr3 |
Promoter: 149896848 - 149898848 | GSE27584 |
chr3 |
Promoter: 149896848 - 149898848 | GSE27584 |
chr3 |
Promoter: 149896848 - 149898848 | GSE27584 |
chr3 |
Promoter: 149896848 - 149898848 | Agilent_014791_44K |