| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 1894 |
Name | ECT2 |
Synonym | ARHGEF31;epithelial cell transforming 2;ECT2;epithelial cell transforming 2 |
Definition | epithelial cell transforming sequence 2 oncogene|epithelial cell-transforming sequence 2 oncogene|protein ECT2 |
Position | 3q26.1-q26.2 |
Gene Type | protein-coding |
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TSG scores |
Description |
| TUSON ranking | 6308 |
TUSON P-value | 1 |
| Caution | This gene might be oncogene according to our integrated oncogene list. |
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Pathways and Diseases |
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Pathway | Signaling by Rho GTPases;Reactome;REACT:11044 |
Pathway | Signaling by GPCR;Reactome;REACT:14797 |
Pathway | Signalling by NGF;Reactome;REACT:11061 |
Pathway | PLK1 signaling events;PID Curated;200087 |
Pathway | Regulation of RhoA activity;PID Curated;200050 |
Disease | Cancer;FunDO |
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External Links |
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Links to Entrez Gene | 1894 |
Links to all GeneRIF Items | 1894 |
Links to iHOP | 1894 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>1894 : length: 2652 atggctgaaaatagtgtattaacatccactactgggaggactagcttggcagactcttcc atttttgattctaaagttactgagatttccaaggaaaacttacttattggatctacttca tatgtagaagaagagatgcctcagattgaaacaagagtgatattggttcaagaagctgga aaacaagaagaacttataaaagccttaaaggacattaaagtgggctttgtaaagatggag tcagtggaagaatttgaaggtttggattctccggaatttgaaaatgtatttgtagtcacg gactttcaggattctgtctttaatgacctctacaaggctgattgtagagttattggacca ccagttgtattaaattgttcacaaaaaggagagcctttgccattttcatgtcgcccgttg tattgtacaagtatgatgaatctagtactatgctttactggatttaggaaaaaagaagaa ctagtcaggttggtgacattggtccatcacatgggtggagttattcgaaaagactttaat tcaaaagttacacatttggtggcaaattgtacacaaggagaaaaattcagggttgctgtg agtctaggtactccaattatgaagccagaatggatttataaagcttgggaaaggcggaat gaacaggatttctatgcagcagttgatgactttagaaatgaatttaaagttcctccattt caagattgtattttaagtttcctgggattttcagatgaagagaaaaccaatatggaagaa atgactgaaatgcaaggaggtaaatatttaccgcttggagatgaaagatgcactcacctt gtagttgaagagaatatagtaaaagatcttccctttgaaccttcaaagaaactttatgtt gtcaagcaagagtggttctggggaagcattcaaatggatgcccgagctggagaaactatg tatttatatgaaaaggcaaatactcctgagctcaagaaatcagtgtcaatgctttctcta aatacccctaacagcaatcgcaaacgacgtcgtttaaaagaaacacttgctcagctttca agagagacagacgtgtcaccatttccaccccgtaagcgcccatcagctgagcattccctt tccatagggtcactcctagatatctccaacacaccagagtctagcattaactatggagac accccaaagtcttgtactaagtcttctaaaagctccactccagttccttcaaagcagtca gcaaggtggcaagttgcaaaagagctttatcaaactgaaagtaattatgttaatatattg gcaacaattattcagttatttcaagtaccattggaagaggaaggacaacgtggtggacct atccttgcaccagaggagattaagactatttttggtagcatcccagatatctttgatgta cacactaagataaaggatgatcttgaagaccttatagttaattgggatgagagcaaaagc attggtgacatttttctgaaatattcaaaagatttggtaaaaacctaccctccctttgta aacttctttgaaatgagcaaggaaacaattattaaatgtgaaaaacagaaaccaagattt catgcttttctcaagataaaccaagcaaaaccagaatgtggacggcagagccttgttgaa cttcttatccgaccagtacagaggttacccagtgttgcattacttttaaatgatcttaag aagcatacagctgatgaaaatccagacaaaagcactttagaaaaagctattggatcactg aaggaagtaatgacgcatattaatgaggataagagaaaaacagaagctcaaaagcaaatt tttgatgttgtttatgaagtagatggatgcccagctaatcttttatcttctcaccgaagc ttagtacagcgggttgaaacaatttctctaggtgagcacccctgtgacagaggagaacaa gtaactctcttcctcttcaatgattgcctagagatagcaagaaaacggcacaaggttatt ggcacttttaggagtcctcatggccaaacccgacccccagcttctcttaagcatattcac ctaatgcctctttctcagattaagaaggtattggacataagagagacagaagattgccat aatgcttttgccttgcttgtgaggccaccaacagagcaggcaaatgtgctactcagtttc cagatgacatcagatgaacttccaaaagaaaactggctaaagatgctgtgtcgacatgta gctaacaccatttgtaaagcagatgctgagaatcttatttatactgctgatccagaatcc tttgaagtaaatacaaaagatatggacagtacattgagtagagcatcaagagcaataaaa aagacttcaaaaaaggttacaagagcattctctttctccaaaactccaaaaagagctctt cgaagggctcttatgacatcccacggctcagtggagggaagaagtccttccagcaatgat aagcatgtaatgagtcgtctttctagcacatcatcattagcaggtatcccttctccctcc cttgtcagccttccttccttctttgaaaggagaagtcatacgttaagtagatctacaact catttgatatga |
Protein Sequence |
>1894 : length: 883 MAENSVLTSTTGRTSLADSSIFDSKVTEISKENLLIGSTSYVEEEMPQIETRVILVQEAG KQEELIKALKDIKVGFVKMESVEEFEGLDSPEFENVFVVTDFQDSVFNDLYKADCRVIGP PVVLNCSQKGEPLPFSCRPLYCTSMMNLVLCFTGFRKKEELVRLVTLVHHMGGVIRKDFN SKVTHLVANCTQGEKFRVAVSLGTPIMKPEWIYKAWERRNEQDFYAAVDDFRNEFKVPPF QDCILSFLGFSDEEKTNMEEMTEMQGGKYLPLGDERCTHLVVEENIVKDLPFEPSKKLYV VKQEWFWGSIQMDARAGETMYLYEKANTPELKKSVSMLSLNTPNSNRKRRRLKETLAQLS RETDVSPFPPRKRPSAEHSLSIGSLLDISNTPESSINYGDTPKSCTKSSKSSTPVPSKQS ARWQVAKELYQTESNYVNILATIIQLFQVPLEEEGQRGGPILAPEEIKTIFGSIPDIFDV HTKIKDDLEDLIVNWDESKSIGDIFLKYSKDLVKTYPPFVNFFEMSKETIIKCEKQKPRF HAFLKINQAKPECGRQSLVELLIRPVQRLPSVALLLNDLKKHTADENPDKSTLEKAIGSL KEVMTHINEDKRKTEAQKQIFDVVYEVDGCPANLLSSHRSLVQRVETISLGEHPCDRGEQ VTLFLFNDCLEIARKRHKVIGTFRSPHGQTRPPASLKHIHLMPLSQIKKVLDIRETEDCH NAFALLVRPPTEQANVLLSFQMTSDELPKENWLKMLCRHVANTICKADAENLIYTADPES FEVNTKDMDSTLSRASRAIKKTSKKVTRAFSFSKTPKRALRRALMTSHGSVEGRSPSSND KHVMSRLSSTSSLAGIPSPSLVSLPSFFERRSHTLSRSTTHLI |