| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 1894 |
Name | ECT2 |
Synonymous | ARHGEF31;epithelial cell transforming 2;ECT2;epithelial cell transforming 2 |
Definition | epithelial cell transforming sequence 2 oncogene|epithelial cell-transforming sequence 2 oncogene|protein ECT2 |
Position | 3q26.1-q26.2 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] |
 |
Transcription Factors [Top] |
|
Regulation From TransFac database |
|---|
| ECT2(h) + ATP --> ECT2(h){p} + ADP (phosphorylation) |
| MgcRacGAP(h) + ECT2(h) <==> MgcRacGAP(h):ECT2(h) (binding) |
| ECT2(h) + ATP --> ECT2(h){pT342} + ADP (phosphorylation) |
| plk1(h) + MgcRacGAP(h) + ECT2(h) <==> plk1(h):MgcRacGAP(h):ECT2(h) (binding) |
| ECT2(h) --> ECT2(h) (expression). |
| ECT2-isoform1(h) + 2 ATP --Cdk1-isoform1(h):cyclinB1(h)--> ECT2-isoform1(h){pT814}{pT412} + 2 ADP (phosphorylation) |
| ECT2-isoform1(h) + ATP --plk1(m.s.)--> ECT2-isoform1(h){p} + ADP (phosphorylation) |
| plk1(m.s.) + ECT2-isoform1(h) <==> plk1(m.s.):ECT2-isoform1(h) (binding) |
| ECT2(h) --> ECT2-isoform1(h) (expression). |
| ECT2(h) --> ECT2-isoform2(h) (expression). |
Post Transcriptional Modification [Top] | |||
|
Location (AA) |
PTM type |
Literature |
Database |
|---|---|---|---|
| 328 | Phosphothreonine. | Swiss-Prot 53.0 | |
| 411 | Phosphoserine | 15302935 | Phospho.ELM 6.0 |
| 417 | Phosphoserine | 15302935 | Phospho.ELM 6.0 |
| 342 | Phosphothreonine (CDK1) | 16170345 | Phospho.ELM 6.0 |
| 413 | Phosphothreonine (CDK1) | 16247472 | Phospho.ELM 6.0 |
| 815 | Phosphothreonine (CDK1) | 16247472 | Phospho.ELM 6.0 |
Methylation Profile [Top] | ||
There is no record for ECT2 | ||