| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 1959 |
Name | EGR2 |
Synonym | AT591|CMT1D|CMT4E|KROX20;early growth response 2;EGR2;early growth response 2 |
Definition | E3 SUMO-protein ligase EGR2|KROX-20, Drosophila, homolog (early growth response-2)|early growth response protein 2|zinc finger protein Krox-20 |
Position | 10q21.1 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 6377 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Calcineurin-regulated NFAT-dependent transcription in lymphocytes;PID Curated;200039 |
Pathway | IL4-mediated signaling events;PID Curated;200018 |
Disease | Charcot-Marie-Tooth disease, type 1D;OMIM |
Disease | Polyneuropathy;FunDO |
Disease | peripheral demyelinating neuropathies;GAD |
Disease | Charcot-Marie-Tooth disease;FunDO |
Disease | Neuropathy, congenital hypomyelinating, 1;OMIM |
Disease | Dejerine-Sottas neuropathy;OMIM |
Disease | CARDIOVASCULAR;GAD |
Disease | Charcot-Marie-Tooth type 1 disease;GAD |
Disease | neuropathy;GAD |
Disease | NEUROLOGICAL;GAD |
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External Links |
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Links to Entrez Gene | 1959 |
Links to all GeneRIF Items | 1959 |
Links to iHOP | 1959 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>1959 : length: 1431 atgatgaccgccaaggccgtagacaaaatcccagtaactctcagtggttttgtgcaccag ctgtctgacaacatctacccggtggaggacctcgccgccacgtcggtgaccatctttccc aatgccgaactgggaggcccctttgaccagatgaacggagtggccggagatggcatgatc aacattgacatgactggagagaagaggtcgttggatctcccatatcccagcagctttgct cccgtctctgcacctagaaaccagaccttcacttacatgggcaagttctccattgaccct cagtaccctggtgccagctgctacccagaaggcataatcaatattgtgagtgcaggcatc ttgcaaggggtcacttccccagcttcaaccacagcctcatccagcgtcacctctgcctcc cccaacccactggccacaggacccctgggtgtgtgcaccatgtcccagacccagcctgac ctggaccacctgtactctccgccaccgcctcctcctccttattctggctgtgcaggagac ctctaccaggacccttctgcgttcctgtcagcagccaccacctccacctcttcctctctg gcctacccaccacctccttcctatccatcccccaagccagccacggacccaggtctcttc ccaatgatcccagactatcctggattctttccatctcagtgccagagagacctacatggt acagctggcccagaccgtaagccctttccctgcccactggacaccctgcgggtgccccct ccactcactccactctctacaatccgtaactttaccctggggggccccagtgctggggtg accggaccaggggccagtggaggcagcgagggaccccggctgcctggtagcagctcagca gcagcagcagccgccgccgccgccgcctataacccacaccacctgccactgcggcccatt ctgaggcctcgcaagtaccccaacagacccagcaagacgccggtgcacgagaggccctac ccgtgcccagcagaaggctgcgaccggcggttctcccgctctgacgagctgacacggcac atccgaatccacactgggcataagcccttccagtgtcggatctgcatgcgcaacttcagc cgcagtgaccacctcaccacccatatccgcacccacaccggtgagaagcccttcgcctgt gactactgtggccgaaagtttgcccggagtgatgagaggaagcgccacaccaagatccac ctgagacagaaagagcggaaaagcagtgccccctctgcatcggtgccagccccctctaca gcctcctgctctgggggcgtgcagcctgggggtaccctgtgcagcagtaacagcagcagt cttggcggagggccgctcgccccttgctcctctcggacccggacaccttga |
Protein Sequence |
>1959 : length: 476 MMTAKAVDKIPVTLSGFVHQLSDNIYPVEDLAATSVTIFPNAELGGPFDQMNGVAGDGMI NIDMTGEKRSLDLPYPSSFAPVSAPRNQTFTYMGKFSIDPQYPGASCYPEGIINIVSAGI LQGVTSPASTTASSSVTSASPNPLATGPLGVCTMSQTQPDLDHLYSPPPPPPPYSGCAGD LYQDPSAFLSAATTSTSSSLAYPPPPSYPSPKPATDPGLFPMIPDYPGFFPSQCQRDLHG TAGPDRKPFPCPLDTLRVPPPLTPLSTIRNFTLGGPSAGVTGPGASGGSEGPRLPGSSSA AAAAAAAAAYNPHHLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRH IRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIH LRQKERKSSAPSASVPAPSTASCSGGVQPGGTLCSSNSSSLGGGPLAPCSSRTRTP |