| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 2049 |
Name | EPHB3 |
Synonym | ETK2|HEK2|TYRO6;EPH receptor B3;EPHB3;EPH receptor B3 |
Definition | EK2|EPH-like kinase 2|EPH-like tyrosine kinase 2|EPH-like tyrosine kinase-2|embryonic kinase 2|ephrin type-B receptor 3|human embryo kinase 2|tyrosine-protein kinase TYRO6 |
Position | 3q27.1 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 6581 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Axon guidance;KEGG PATHWAY;hsa04360 |
Pathway | EPHB forward signaling;PID Curated;200041 |
Pathway | EphrinB-EPHB pathway;PID Curated;200141 |
Pathway | Angiogenesis;PANTHER;P00005 |
|
External Links |
|
Links to Entrez Gene | 2049 |
Links to all GeneRIF Items | 2049 |
Links to iHOP | 2049 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>2049 : length: 2997 atggccagagcccgcccgccgccgccgccgtcgccgccgccggggcttctgccgctgctc cctccgctgctgctgctgccgctgctgctgctgcccgccggctgccgggcgctggaagag accctcatggacacaaaatgggtaacatctgagttggcgtggacatctcatccagaaagt gggtgggaagaggtgagtggctacgatgaggccatgaatcccatccgcacataccaggtg tgtaatgtgcgcgagtcaagccagaacaactggcttcgcacggggttcatctggcggcgg gatgtgcagcgggtctacgtggagctcaagttcactgtgcgtgactgcaacagcatcccc aacatccccggctcctgcaaggagaccttcaacctcttctactacgaggctgacagcgat gtggcctcagcctcctcccccttctggatggagaacccctacgtgaaagtggacaccatt gcacccgatgagagcttctcgcggctggatgccggccgtgtcaacaccaaggtgcgcagc tttgggccactttccaaggctggcttctacctggccttccaggaccagggcgcctgcatg tcgctcatctccgtgcgcgccttctacaagaagtgtgcatccaccaccgcaggcttcgca ctcttccccgagaccctcactggggcggagcccacctcgctggtcattgctcctggcacc tgcatccctaacgccgtggaggtgtcggtgccactcaagctctactgcaacggcgatggg gagtggatggtgcctgtgggtgcctgcacctgtgccaccggccatgagccagctgccaag gagtcccagtgccgcccctgtccccctgggagctacaaggcgaagcagggagaggggccc tgcctcccatgtccccccaacagccgtaccacctccccagccgccagcatctgcacctgc cacaataacttctaccgtgcagactcggactctgcggacagtgcctgtaccaccgtgcca tctccaccccgaggtgtgatctccaatgtgaatgaaacctcactgatcctcgagtggagt gagccccgggacctgggtggccgggatgacctcctgtacaatgtcatctgcaagaagtgc catggggctggaggggcctcagcctgctcacgctgtgatgacaacgtggagtttgtgcct cggcagctgggcctgacggagcgccgggtccacatcagccatctgctggcccacacgcgc tacacctttgaggtgcaggcggtcaacggtgtctcgggcaagagccctctgccgcctcgt tatgcggccgtgaatatcaccacaaaccaggctgccccgtctgaagtgcccacactacgc ctgcacagcagctcaggcagcagcctcaccctatcctgggcacccccagagcggcccaac ggagtcatcctggactacgagatgaagtactttgagaagagcgagggcatcgcctccaca gtgaccagccagatgaactccgtgcagctggacgggcttcggcctgacgcccgctatgtg gtccaggtccgtgcccgcacagtagctggctatgggcagtacagccgccctgccgagttt gagaccacaagtgagagaggctctggggcccagcagctccaggagcagcttcccctcatc gtgggctccgctacagctgggcttgtcttcgtggtggctgtcgtggtcatcgctatcgtc tgcctcaggaagcagcgacacggctctgattcggagtacacggagaagctgcagcagtac attgctcctggaatgaaggtttatattgacccttttacctacgaggaccctaatgaggct gttcgggagtttgccaaggagatcgacgtgtcctgcgtcaagatcgaggaggtgatcgga gctggggaatttggggaagtgtgccgtggtcgactgaaacagcctggccgccgagaggtg tttgtggccatcaagacgctgaaggtgggctacaccgagaggcagcggcgggacttccta agcgaggcctccatcatgggtcagtttgatcaccccaatataatccggctcgagggcgtg gtcaccaaaagtcggccagttatgatcctcactgagttcatggaaaactgcgccctggac tccttcctccggctcaacgatgggcagttcacggtcatccagctggtgggcatgttgcgg ggcattgctgccggcatgaagtacctgtccgagatgaactatgtgcaccgcgacctggct gctcgcaacatccttgtcaacagcaacctggtctgcaaagtctcagactttggcctctcc cgcttcctggaggatgacccctccgatcctacctacaccagttccctgggcgggaagatc cccatccgctggactgccccagaggccatagcctatcggaagttcacttctgctagtgat gtctggagctacggaattgtcatgtgggaggtcatgagctatggagagcgaccctactgg gacatgagcaaccaggatgtcatcaatgccgtggagcaggattaccggctgccaccaccc atggactgtcccacagcactgcaccagctcatgctggactgctgggtgcgggaccggaac ctcaggcccaaattctcccagattgtcaataccctggacaagctcatccgcaatgctgcc agcctcaaggtcattgccagcgctcagtctggcatgtcacagcccctcctggaccgcacg gtcccagattacacaaccttcacgacagttggtgattggctggatgccatcaagatgggg cggtacaaggagagcttcgtcagtgcggggtttgcatcttttgacctggtggcccagatg acggcagaagacctgctccgtattggggtcaccctggccggccaccagaagaagatcctg agcagtatccaggacatgcggctgcagatgaaccagacgctgcctgtgcaggtctga |
Protein Sequence |
>2049 : length: 998 MARARPPPPPSPPPGLLPLLPPLLLLPLLLLPAGCRALEETLMDTKWVTSELAWTSHPES GWEEVSGYDEAMNPIRTYQVCNVRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIP NIPGSCKETFNLFYYEADSDVASASSPFWMENPYVKVDTIAPDESFSRLDAGRVNTKVRS FGPLSKAGFYLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGT CIPNAVEVSVPLKLYCNGDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGP CLPCPPNSRTTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWS EPRDLGGRDDLLYNVICKKCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTR YTFEVQAVNGVSGKSPLPPRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPN GVILDYEMKYFEKSEGIASTVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEF ETTSERGSGAQQLQEQLPLIVGSATAGLVFVVAVVVIAIVCLRKQRHGSDSEYTEKLQQY IAPGMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREV FVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALD SFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLS RFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYW DMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAA SLKVIASAQSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQM TAEDLLRIGVTLAGHQKKILSSIQDMRLQMNQTLPVQV |