Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

2049

Name

EPHB3

Synonymous

ETK2|HEK2|TYRO6;EPH receptor B3;EPHB3;EPH receptor B3

Definition

EK2|EPH-like kinase 2|EPH-like tyrosine kinase 2|EPH-like tyrosine kinase-2|embryonic kinase 2|ephrin type-B receptor 3|human embryo kinase 2|tyrosine-protein kinase TYRO6

Position

3q27.1

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

There is no record for EPHB3

Transcription Factors   [Top]

Regulation From TransFac database

ephrin-B1(m.s.) + EPHB3(h) <==> ephrin-B1(m.s.):EPHB3(h) (binding)
EPHB3(h) --> EPHB3(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

351N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
445N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
608Phosphotyrosine (by autocatalysis) (Bysimilarity).Swiss-Prot 53.0
614Phosphotyrosine (by autocatalysis) (Bysimilarity).Swiss-Prot 53.0
792Phosphotyrosine (by autocatalysis)(Potential).Swiss-Prot 53.0
942Phosphotyrosine (by autocatalysis) (Bysimilarity).Swiss-Prot 53.0
608Phosphotyrosine15951569Phospho.ELM 6.0
614Phosphotyrosine (EphB3)9674711Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr3

Promoter: 185760781 - 185762781Agilent_014791

chr3

Promoter: 185760781 - 185762781GoldenGate_Methylation_Cancer_Panel_I

chr3

Promoter: 185760781 - 185762781GSE27584

chr3

Promoter: 185760781 - 185762781Agilent_014791_44K


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