General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
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Gene ID | 2146 |
Name | EZH2 |
Synonym | ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2;enhancer of zeste 2 polycomb repressive complex 2 subunit;EZH2;enhancer of zeste 2 polycomb repressive complex 2 subunit |
Definition | enhancer of zeste homolog 2|histone-lysine N-methyltransferase EZH2|lysine N-methyltransferase 6 |
Position | 7q35-q36 |
Gene Type | protein-coding |
TSG scores |
Description |
TUSON ranking | 6731 |
TUSON P-value | 1 |
Caution | This gene might be oncogene according to our integrated oncogene list. |
External Links |
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Links to Entrez Gene | 2146 |
Links to all GeneRIF Items | 2146 |
Links to iHOP | 2146 |
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>2146 : length: 2241 atgggccagactgggaagaaatctgagaagggaccagtttgttggcggaagcgtgtaaaa tcagagtacatgcgactgagacagctcaagaggttcagacgagctgatgaagtaaagagt atgtttagttccaatcgtcagaaaattttggaaagaacggaaatcttaaaccaagaatgg aaacagcgaaggatacagcctgtgcacatcctgacttctgtgagctcattgcgcgggact agggagtgttcggtgaccagtgacttggattttccaacacaagtcatcccattaaagact ctgaatgcagttgcttcagtacccataatgtattcttggtctcccctacagcagaatttt atggtggaagatgaaactgttttacataacattccttatatgggagatgaagttttagat caggatggtactttcattgaagaactaataaaaaattatgatgggaaagtacacggggat agagaatgtgggtttataaatgatgaaatttttgtggagttggtgaatgcccttggtcaa tataatgatgatgacgatgatgatgatggagacgatcctgaagaaagagaagaaaagcag aaagatctggaggatcaccgagatgataaagaaagccgcccacctcggaaatttccttct gataaaatttttgaagccatttcctcaatgtttccagataagggcacagcagaagaacta aaggaaaaatataaagaactcaccgaacagcagctcccaggcgcacttcctcctgaatgt acccccaacatagatggaccaaatgctaaatctgttcagagagagcaaagcttacactcc tttcatacgcttttctgtaggcgatgttttaaatatgactgcttcctacatccttttcat gcaacacccaacacttataagcggaagaacacagaaacagctctagacaacaaaccttgt ggaccacagtgttaccagcatttggagggagcaaaggagtttgctgctgctctcaccgct gagcggataaagaccccaccaaaacgtccaggaggccgcagaagaggacggcttcccaat aacagtagcaggcccagcacccccaccattaatgtgctggaatcaaaggatacagacagt gatagggaagcagggactgaaacggggggagagaacaatgataaagaagaagaagagaag aaagatgaaacttcgagctcctctgaagcaaattctcggtgtcaaacaccaataaagatg aagccaaatattgaacctcctgagaatgtggagtggagtggtgctgaagcctcaatgttt agagtcctcattggcacttactatgacaatttctgtgccattgctaggttaattgggacc aaaacatgtagacaggtgtatgagtttagagtcaaagaatctagcatcatagctccagct cccgctgaggatgtggatactcctccaaggaaaaagaagaggaaacaccggttgtgggct gcacactgcagaaagatacagctgaaaaaggacggctcctctaaccatgtttacaactat caaccctgtgatcatccacggcagccttgtgacagttcgtgcccttgtgtgatagcacaa aatttttgtgaaaagttttgtcaatgtagttcagagtgtcaaaaccgctttccgggatgc cgctgcaaagcacagtgcaacaccaagcagtgcccgtgctacctggctgtccgagagtgt gaccctgacctctgtcttacttgtggagccgctgaccattgggacagtaaaaatgtgtcc tgcaagaactgcagtattcagcggggctccaaaaagcatctattgctggcaccatctgac gtggcaggctgggggatttttatcaaagatcctgtgcagaaaaatgaattcatctcagaa tactgtggagagattatttctcaagatgaagctgacagaagagggaaagtgtatgataaa tacatgtgcagctttctgttcaacttgaacaatgattttgtggtggatgcaacccgcaag ggtaacaaaattcgttttgcaaatcattcggtaaatccaaactgctatgcaaaagttatg atggttaacggtgatcacaggataggtatttttgccaagagagccatccagactggcgaa gagctgttttttgattacagatacagccaggctgatgccctgaagtatgtcggcatcgaa agagaaatggaaatcccttga |
Protein Sequence |
>2146 : length: 746 MGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEW KQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNF MVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQ YNDDDDDDDGDDPEEREEKQKDLEDHRDDKESRPPRKFPSDKIFEAISSMFPDKGTAEEL KEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFH ATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPPKRPGGRRRGRLPN NSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSSSEANSRCQTPIKM KPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPA PAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCPCVIAQ NFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVS CKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDK YMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGE ELFFDYRYSQADALKYVGIEREMEIP |