General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
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Gene ID | 2146 |
Name | EZH2 |
Synonymous | ENX-1|ENX1|EZH1|EZH2b|KMT6|KMT6A|WVS|WVS2;enhancer of zeste 2 polycomb repressive complex 2 subunit;EZH2;enhancer of zeste 2 polycomb repressive complex 2 subunit |
Definition | enhancer of zeste homolog 2|histone-lysine N-methyltransferase EZH2|lysine N-methyltransferase 6 |
Position | 7q35-q36 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] |
Transcription Factors [Top] |
Regulation From TransFac database |
hdac2(h) + EZH2(h) <==> hdac2(h):EZH2(h) (binding) | EZH2(h) + HDAC1(h) <==> EZH2(h):HDAC1(h) (binding) | EZH2(h) + EED(h) <==> EED(h):EZH2(h) (binding) | EED(h) + EZH2(h) + HDAC1(h) + hdac2(h) <==> EED(h):EZH2(h):HDAC1(h):hdac2(h) (binding) | EZH2(h) + DIPA(h) <==> EZH2(h):DIPA(h) (binding) | EZH2(h) + POLA2(h) <==> EZH2(h):POLA2(h) (binding) | EZH2(h) --> EZH2(h) (expression). | EZH2(h) --> EZH2(h) (expression). |
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Post Transcriptional Modification [Top] | |||
Location (AA) |
PTM type |
Literature |
Database |
487 | Phosphothreonine. | Swiss-Prot 53.0 | 487 | Phosphothreonine | 15302935;17081983 | Phospho.ELM 6.0 | 21 | Phosphoserine | 16224021 | Phospho.ELM 6.0 |
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Methylation Profile [Top] | ||
Chromosome |
Location |
Source |
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chr7 |
Promoter: 148211847 - 148213847 | Agilent_014791 |
chr7 |
Promoter: 148211847 - 148213847 | GSE27584 |
chr7 |
Promoter: 148211847 - 148213847 | GSE27584 |
chr7 |
Promoter: 148211847 - 148213847 | Agilent_014791_44K |