| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 2521 |
Name | FUS |
Synonym | ALS6|ETM4|FUS1|HNRNPP2|POMP75|TLS;FUS RNA binding protein;FUS;FUS RNA binding protein |
Definition | 75 kDa DNA-pairing protein|RNA-binding protein FUS|fus-like protein|fused in sarcoma|fusion gene in myxoid liposarcoma|heterogeneous nuclear ribonucleoprotein P2|oncogene FUS|oncogene TLS|translocated in liposarcoma protein |
Position | 16p11.2 |
Gene Type | protein-coding |
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TSG scores |
Description |
| TUSON ranking | 7429 |
TUSON P-value | 1 |
| Caution | This gene might be oncogene according to our integrated oncogene list. |
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Pathways and Diseases |
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Pathway | mRNA Splicing - Major Pathway;PID Reactome;500866 |
Pathway | Gene Expression;Reactome;REACT:71 |
Pathway | mRNA Processing;Reactome;REACT:1675 |
Disease | Amyotrophic lateral sclerosis;KEGG DISEASE;H00058 |
Disease | Cancers;KEGG DISEASE |
Disease | Amyotrophic lateral sclerosis 6, autosomal recessive;OMIM |
Disease | Cancers of soft tissues and bone;KEGG DISEASE |
Disease | Myxoid liposarcoma;KEGG DISEASE;H00049 |
Disease | Nervous system diseases;KEGG DISEASE |
Disease | Neurodegenerative diseases;KEGG DISEASE |
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External Links |
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Links to Entrez Gene | 2521 |
Links to all GeneRIF Items | 2521 |
Links to iHOP | 2521 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>2521 : length: 1578 atggcctcaaacgattatacccaacaagcaacccaaagctatggggcctaccccacccag cccgggcagggctattcccagcagagcagtcagccctacggacagcagagttacagtggt tatagccagtccacggacacttcaggctatggccagagcagctattcttcttatggccag agccagaacagctatggaactcagtcaactccccagggatatggctcgactggcggctat ggcagtagccagagctcccaatcgtcttacgggcagcagtcctcctaccctggctatggc cagcagccagctcccagcagcacctcgggaagttacggtagcagttctcagagcagcagc tatgggcagccccagagtgggagctacagccagcagcctagctatggtggacagcagcaa agctatggacagcagcaaagctataatccccctcagggctatggacagcagaaccagtac aacagcagcagtggtggtggaggtggaggtggaggtggaggtaactatggccaagatcaa tcctccatgagtagtggtggtggcagtggtggcggttatggcaatcaagaccagagtggt ggaggtggcagcggtggctatggacagcaggaccgtggaggccgcggcaggggtggcagt ggtggcggcggcggcggcggcggtggtggttacaaccgcagcagtggtggctatgaaccc agaggtcgtggaggtggccgtggaggcagaggtggcatgggcggaagtgaccgtggtggc ttcaataaatttggtggccctcgggaccaaggatcacgtcatgactccgaacaggataat tcagacaacaacaccatctttgtgcaaggcctgggtgagaatgttacaattgagtctgtg gctgattacttcaagcagattggtattattaagacaaacaagaaaacgggacagcccatg attaatttgtacacagacagggaaactggcaagctgaagggagaggcaacggtctctttt gatgacccaccttcagctaaagcagctattgactggtttgatggtaaagaattctccgga aatcctatcaaggtctcatttgctactcgccgggcagactttaatcggggtggtggcaat ggtcgtggaggccgagggcgaggaggacccatgggccgtggaggctatggaggtggtggc agtggtggtggtggccgaggaggatttcccagtggaggtggtggcggtggaggacagcag cgagctggtgactggaagtgtcctaatcccacctgtgagaatatgaacttctcttggagg aatgaatgcaaccagtgtaaggcccctaaaccagatggcccaggagggggaccaggtggc tctcacatggggggtaactacggggatgatcgtcgtggtggcagaggaggctatgatcga ggcggctaccggggccgcggcggggaccgtggaggcttccgagggggccggggtggtggg gacagaggtggctttggccctggcaagatggattccaggggtgagcacagacaggatcgc agggagaggccgtattaa |
Protein Sequence |
>2521 : length: 525 MASNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQ SQNSYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSS YGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQ SSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEP RGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESV ADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSG NPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQ RAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDR GGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEHRQDRRERPY |