| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 26018 |
Name | LRIG1 |
Synonym | LIG-1|LIG1;leucine-rich repeats and immunoglobulin-like domains 1;LRIG1;leucine-rich repeats and immunoglobulin-like domains 1 |
Definition | leucine-rich repeat protein LRIG1|leucine-rich repeats and immunoglobulin-like domains protein 1|ortholog of mouse integral membrane glycoprotein LIG-1 |
Position | 3p14 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 9997 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Internalization of ErbB1;PID Curated;200146 |
Pathway | Signaling by EGFR;PID Reactome;500510 |
Pathway | ErbB4 signaling events;PID Curated;200009 |
Disease | Cancer;FunDO |
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External Links |
|
Links to Entrez Gene | 26018 |
Links to all GeneRIF Items | 26018 |
Links to iHOP | 26018 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>26018 : length: 3282 atggcgcggccggtccggggagggctcggggccccgcgccgctcgccttgccttctcctt ctctggctgcttttgcttcggctggagccggtgaccgccgcggccggcccgcgggcgccc tgcgcggccgcctgcacttgcgctggggactcgctggactgcggtgggcgcgggctggct gcgttgcccggggacctgccctcctggacgcggagcctaaacctgagttacaacaaactc tctgagattgaccctgctggttttgaggacttgccgaacctacaggaagtgtacctcaat aataatgagttgacagcggtaccatccctgggcgctgcttcatcacatgtcgtctctctc tttctgcagcacaacaagattcgcagcgtggaggggagccagctgaaggcctacctttcc ttagaagtgttagatctgagtttgaacaacatcacggaagtgcggaacacctgctttcca cacggaccgcctataaaggagctcaacctggcaggcaatcggattggcaccctggagttg ggagcatttgatggtctgtcacggtcgctgctaactcttcgcctgagcaaaaacaggatc acccagcttcctgtaagagcattcaagctacccaggctgacacaactggacctcaatcgg aacaggattcggctgatagagggcctcaccttccaggggctcaacagcttggaggtgctg aagcttcagcgaaacaacatcagcaaactgacagatggggccttctggggactgtccaag atgcatgtgctgcacctggagtacaacagcctggtagaagtgaacagcggctcgctctac ggcctcacggccctgcatcagctccacctcagcaacaattccatcgctcgcattcaccgc aagggctggagcttctgccagaagctgcatgagttggtcctgtccttcaacaacctgaca cggctggacgaggagagcctggccgagctgagcagcctgagtgtcctgcgtctcagccac aattccatcagccacattgcggagggtgccttcaagggactcaggagcctgcgagtcttg gatctggaccataacgagatttcgggcacaatagaggacacgagcggcgccttctcaggg ctcgacagcctcagcaagctgactctgtttggaaacaagatcaagtctgtggctaagaga gcattctcggggctggaaggcctggagcacctgaaccttggagggaatgcgatcagatct gtccagtttgatgcctttgtgaagatgaagaatcttaaagagctccatatcagcagcgac agcttcctgtgtgactgccagctgaagtggctgcccccgtggctaattggcaggatgctg caggcctttgtgacagccacctgtgcccacccagaatcactgaagggtcagagcattttc tctgtgccaccagagagtttcgtgtgcgatgacttcctgaagccacagatcatcacccag ccagaaaccaccatggctatggtgggcaaggacatccggtttacatgctcagcagccagc agcagcagctcccccatgacctttgcctggaagaaagacaatgaagtcctgaccaatgca gacatggagaactttgtccacgtccacgcgcaggacggggaagtgatggagtacaccacc atcctgcacctccgtcaggtcactttcgggcacgagggccgctaccaatgtgtcatcacc aaccactttggctccacctattcacataaggccaggctcaccgtgaatgtgttgccatca ttcaccaaaacgccccacgacataaccatccggaccaccaccatggcccgcctcgaatgt gctgccacaggtcacccaaaccctcagattgcctggcagaaggatggaggcacggatttc cccgctgcccgtgagcgacgcatgcatgtcatgccggatgacgacgtgtttttcatcact gatgtgaaaatagatgacgcaggggtttacagctgtactgctcagaactcagccggttct atttcagctaatgccaccctgactgtcctagagaccccatccttggtggtccccttggaa gaccgtgtggtatctgtgggagaaacagtggccctccaatgcaaagccacggggaaccct ccgccccgcatcacctggttcaagggggaccgcccgctgagcctcactgagcggcaccac ttgacccctgacaaccagctcctggtggttcagaacgtggtggcagaggatgcgggccga tatacctgtgagatgtccaacaccctgggcacggagcgagctcacagccagctgagcgtc ctgcccgcagcaggctgcaggaaggatgggaccacggtaggcatcttcaccattgctgtc gtgagcagcatcgtcctgacgtcactggtctgggtgtgcatcatctaccagaccaggaag aagagtgaagagtacagtgtcaccaacacagatgaaaccgtcgtgccaccagatgttcca agctacctctcttctcaggggaccctttctgaccgacaagaaaccgtggtcaggaccgag ggtggccctcaggccaatgggcacattgagagcaatggtgtgtgtccaagagatgcaagc cactttccagagcccgacactcacagcgttgcctgcaggcagccaaagctctgtgctggg tctgcgtatcacaaagagccgtggaaagcgatggagaaagctgaagggacacctgggcca cataagatggaacacggtggccgggtcgtatgcagtgactgcaacaccgaagtggactgt tactccaggggacaagccttccacccccagcctgtgtccagagacagcgcacagccaagt gcgccaaatggcccggagccgggtgggagtgaccaagagcattctccacatcaccagtgc agcaggactgccgctgggtcctgccccgagtgccaagggtcgctctaccccagtaaccac gatagaatgctgacggctgtgaagaaaaagccaatggcatctctagatgggaaaggggat tcttcctggactttagcaaggttgtatcacccggactccacagagctacagcctgcatct tcattaacttcaggcagtccagagcgcgcggaagcccagtacttgcttgtttccaatggc cacctccccaaagcatgtgacgccagtcccgagtccacgccactgacaggacagctcccc gggaaacagagggtgccactgctgttggcaccaaaaagctag |
Protein Sequence |
>26018 : length: 1093 MARPVRGGLGAPRRSPCLLLLWLLLLRLEPVTAAAGPRAPCAAACTCAGDSLDCGGRGLA ALPGDLPSWTRSLNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPSLGAASSHVVSL FLQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLEL GAFDGLSRSLLTLRLSKNRITQLPVRAFKLPRLTQLDLNRNRIRLIEGLTFQGLNSLEVL KLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHR KGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVL DLDHNEISGTIEDTSGAFSGLDSLSKLTLFGNKIKSVAKRAFSGLEGLEHLNLGGNAIRS VQFDAFVKMKNLKELHISSDSFLCDCQLKWLPPWLIGRMLQAFVTATCAHPESLKGQSIF SVPPESFVCDDFLKPQIITQPETTMAMVGKDIRFTCSAASSSSSPMTFAWKKDNEVLTNA DMENFVHVHAQDGEVMEYTTILHLRQVTFGHEGRYQCVITNHFGSTYSHKARLTVNVLPS FTKTPHDITIRTTTMARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFIT DVKIDDAGVYSCTAQNSAGSISANATLTVLETPSLVVPLEDRVVSVGETVALQCKATGNP PPRITWFKGDRPLSLTERHHLTPDNQLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSV LPAAGCRKDGTTVGIFTIAVVSSIVLTSLVWVCIIYQTRKKSEEYSVTNTDETVVPPDVP SYLSSQGTLSDRQETVVRTEGGPQANGHIESNGVCPRDASHFPEPDTHSVACRQPKLCAG SAYHKEPWKAMEKAEGTPGPHKMEHGGRVVCSDCNTEVDCYSRGQAFHPQPVSRDSAQPS APNGPEPGGSDQEHSPHHQCSRTAAGSCPECQGSLYPSNHDRMLTAVKKKPMASLDGKGD SSWTLARLYHPDSTELQPASSLTSGSPERAEAQYLLVSNGHLPKACDASPESTPLTGQLP GKQRVPLLLAPKS |