Entrez Gene

Basic Information
Gene ID	26018
Name	LRIG1
Synonymous	LIG-1\|LIG1;leucine-rich repeats and immunoglobulin-like domains 1;LRIG1;leucine-rich repeats and immunoglobulin-like domains 1
Definition	leucine-rich repeat protein LRIG1\|leucine-rich repeats and immunoglobulin-like domains protein 1\|ortholog of mouse integral membrane glycoprotein LIG-1
Position	3p14
Gene Type	protein-coding
Gene Regulation:	Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase [Top]

Regulation From TransFac database
Transcription Factors [Top]
LRIG1(h) --> LRIG1-isoform1(h) (expression).
ErbB1(m.s.) + LRIG-1(h) <==> ErbB1(m.s.):LRIG-1(h) (binding)
ErbB2(m.s.) + LRIG-1(h) <==> ErbB2(m.s.):LRIG-1(h) (binding)
ErbB3(m.s.) + LRIG-1(h) <==> LRIG-1(h):ErbB3(m.s.) (binding)
ErbB4(m.s.) + LRIG-1(h) <==> LRIG-1(h):ErbB4(m.s.) (binding)
c-Cbl(m.s.) + LRIG-1(h) <==> c-Cbl(m.s.):LRIG-1(h) (binding)
LRIG-1(h) + ubiquitin(h) --> LRIG-1(h){ub} (ubiquitination)
LRIG1(h) --> LRIG-1(h) (expression).
LRIG1(h) --> LRIG1-isoform2(h) (expression).
LRIG1-xbb1(h) + ErbB1(h) <==> LRIG1-xbb1(h):ErbB1(h) (binding)
LRIG1-xbb1(h) + ErbB2(h) <==> LRIG1-xbb1(h):ErbB2(h) (binding)
LRIG1-xbb1(h) + ErbB3(h) <==> LRIG1-xbb1(h):ErbB3(h) (binding)
LRIG1-xbb1(h) + ErbB4(h) <==> LRIG1-xbb1(h):ErbB4(h) (binding)
LRIG1(h) --> LRIG1-xbb1(h) (expression).

Location (AA)	PTM type	Database
Post Transcriptional Modification [Top]
74	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
150	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
246	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
292	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
318	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
684	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0