| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 27113 |
Name | BBC3 |
Synonym | JFY-1|JFY1|PUMA;BCL2 binding component 3;BBC3;BCL2 binding component 3 |
Definition | bcl-2-binding component 3|p53 up-regulated modulator of apoptosis |
Position | 19q13.3-q13.4 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 3394 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Activation of PUMA and translocation to mitochondria;PID Reactome;501019 |
Pathway | Huntington's disease;KEGG PATHWAY;hsa05016 |
Pathway | Direct p53 effectors;PID Curated;200101 |
Pathway | Apoptosis;Reactome;REACT:578 |
Pathway | p53 signaling pathway;KEGG PATHWAY;hsa04115 |
Disease | Cancer;FunDO |
Disease | Neck cancer;FunDO |
|
External Links |
|
Links to Entrez Gene | 27113 |
Links to all GeneRIF Items | 27113 |
Links to iHOP | 27113 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>27113 : length: 786 atgaaatttggcatggggtctgcccaggcatgtccatgccaggtgcccagggctgcttcc acgacgtgggtcccctgccagatttgtggccccagggagcgccatggcccgcgcacgcca ggagggcagctccccggagcccgtagagggcctggcccgcgacggcccgcgccccttccc gctcggccgcctggtgccctcggcagtgtcctgcggcctctgcgagcccggcctggctgc cgcccccgccgcccccaccctgctgcccgctgcctacctctgcgcccccaccgccccacc cgccgtcaccgccgccctggggggttcccgctggcctgggggtccccgcagccggccccg aggcccgcgcccggacggtcctcagccctcgctctcgctggcggagcagcacctggagtc gcccgtgcccagcgccccgggggctctggcgggcggtcccacccaggcggccccgggagt ccgcggggaggaggaacagtgggcccgggagatcggggcccagctgcggcggatggcgga cgacctcaacgcacagtacgagcggcggagacaagaggagcagcagcggcaccgcccctc accctggagggtcctgtacaatctcatcatgggactcctgcccttacccaggggccacag agcccccgagatggagcccaattaggtgcctgcacccgcccggtggacgtcagggactcg gggggcaggcccctcccacctcctgacaccctggccagcgcgggggactttctctgcacc atgtag |
Protein Sequence |
>27113 : length: 261 MKFGMGSAQACPCQVPRAASTTWVPCQICGPRERHGPRTPGGQLPGARRGPGPRRPAPLP ARPPGALGSVLRPLRARPGCRPRRPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAP RPAPGRSSALALAGGAAPGVARAQRPGGSGGRSHPGGPGSPRGGGTVGPGDRGPAAADGG RPQRTVRAAETRGAAAAPPLTLEGPVQSHHGTPALTQGPQSPRDGAQLGACTRPVDVRDS GGRPLPPPDTLASAGDFLCTM |