Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

27113

Name

BBC3

Synonymous

JFY-1|JFY1|PUMA;BCL2 binding component 3;BBC3;BCL2 binding component 3

Definition

bcl-2-binding component 3|p53 up-regulated modulator of apoptosis

Position

19q13.3-q13.4

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

Bcl-2(h) + PUMA(h) <==> Bcl-2(h):PUMA(h) (binding)
Bcl-X(h) + PUMA(h) <==> Bcl-X(h):PUMA(h) (binding)
bbc3(h) --> PUMA(h) (expression).
bbc3(h) --> PUMA(h) (expression).
Skp2(m.s.) --/ PUMA(h) (decrease of abundance)
Apak(h) --/ PUMA(h) (decrease of abundance)

Post Transcriptional Modification   [Top]

There is no record for BBC3

Methylation Profile   [Top]

Chromosome

Location

Source

chr19

Promoter: 52425791 - 52427791Agilent_014791

chr19

Promoter: 52425791 - 52427791GSE27584

chr19

Promoter: 52425791 - 52427791Agilent_014791


')