| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 2735 |
Name | GLI1 |
Synonym | GLI;GLI family zinc finger 1;GLI1;GLI family zinc finger 1 |
Definition | GLI-Kruppel family member GLI1|glioma-associated oncogene 1|glioma-associated oncogene homolog 1 (zinc finger protein)|oncogene GLI|zinc finger protein GLI1 |
Position | 12q13.2-q13.3 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 7741 |
TUSON P-value | 1 |
| Caution | This gene might be oncogene according to our integrated oncogene list. |
|
Pathways and Diseases |
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Pathway | Hedgehog signaling pathway;PANTHER;P00025 |
Pathway | Hedgehog signaling events mediated by Gli proteins;PID Curated;200147 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | Basal cell carcinoma;KEGG PATHWAY;hsa05217 |
Pathway | Hedgehog signaling pathway;KEGG PATHWAY;hsa04340 |
Disease | Cancer;FunDO |
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External Links |
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Links to Entrez Gene | 2735 |
Links to all GeneRIF Items | 2735 |
Links to iHOP | 2735 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>2735 : length: 2937 atgagcccatctctgggattcccagcccagatgaatcaccaaaaagggccctcgccttcc tttggggtccagccttgtggtccccatgactctgcccggggtgggatgatcccacatcct cagtcccggggacccttcccaacttgccagctgaagtctgagctggacatgctggttggc aagtgccgggaggaacccttggaaggtgatatgtccagccccaactccacaggcatacag gatcccctgttggggatgctggatgggcgggaggacctcgagagagaggagaagcgtgag cctgaatctgtgtatgaaactgactgccgttgggatggctgcagccaggaatttgactcc caagagcagctggtgcaccacatcaacagcgagcacatccacggggagcggaaggagttc gtgtgccactgggggggctgctccagggagctgaggcccttcaaagcccagtacatgctg gtggttcacatgcgcagacacactggcgagaagccacacaagtgcacgtttgaagggtgc cggaagtcatactcacgcctcgaaaacctgaagacgcacctgcggtcacacacgggtgag aagccatacatgtgtgagcacgagggctgcagtaaagccttcagcaatgccagtgaccga gccaagcaccagaatcggacccattccaatgagaagccgtatgtatgtaagctccctggc tgcaccaaacgctatacagatcctagctcgctgcgaaaacatgtcaagacagtgcatggt cctgacgcccatgtgaccaaacggcaccgtggggatggccccctgcctcgggcaccatcc atttctacagtggagcccaagagggagcgggaaggaggtcccatcagggaggaaagcaga ctgactgtgccagagggtgccatgaagccacagccaagccctggggcccagtcatcctgc agcagtgaccactccccggcagggagtgcagccaatacagacagtggtgtggaaatgact ggcaatgcagggggcagcactgaagacctctccagcttggacgagggaccttgcattgct ggcactggtctgtccactcttcgccgccttgagaacctcaggctggaccagctacatcaa ctccggccaatagggacccggggtctcaaactgcccagcttgtcccacaccggtaccact gtgtcccgccgcgtgggccccccagtctctcttgaacgccgcagcagcagctccagcagc atcagctctgcctatactgtcagccgccgctcctccctggcctctcctttcccccctggc tccccaccagagaatggagcatcctccctgcctggccttatgcctgcccagcactacctg cttcgggcaagatatgcttcagccagagggggtggtacttcgcccactgcagcatccagc ctggatcggataggtggtcttcccatgcctccttggagaagccgagccgagtatccagga tacaaccccaatgcaggggtcacccggagggccagtgacccagcccaggctgctgaccgt cctgctccagctagagtccagaggttcaagagcctgggctgtgtccataccccacccact gtggcagggggaggacagaactttgatccttacctcccaacctctgtctactcaccacag ccccccagcatcactgagaatgctgccatggatgctagagggctacaggaagagccagaa gttgggacctccatggtgggcagtggtctgaacccctatatggacttcccacctactgat actctgggatatgggggacctgaaggggcagcagctgagccttatggagcgaggggtcca ggctctctgcctcttgggcctggtccacccaccaactatggccccaacccctgtccccag caggcctcatatcctgaccccacccaagaaacatggggtgagttcccttcccactctggg ctgtacccaggccccaaggctctaggtggaacctacagccagtgtcctcgacttgaacat tatggacaagtgcaagtcaagccagaacaggggtgcccagtggggtctgactccacagga ctggcaccctgcctcaatgcccaccccagtgaggggcccccacatccacagcctctcttt tcccattacccccagccctctcctccccaatatctccagtcaggcccctatacccagcca ccccctgattatcttccttcagaacccaggccttgcctggactttgattcccccacccat tccacagggcagctcaaggctcagcttgtgtgtaattatgttcaatctcaacaggagcta ctgtgggagggtgggggcagggaagatgcccccgcccaggaaccttcctaccagagtccc aagtttctggggggttcccaggttagcccaagccgtgctaaagctccagtgaacacatat ggacctggctttggacccaacttgcccaatcacaagtcaggttcctatcccaccccttca ccatgccatgaaaattttgtagtgggggcaaatagggcttcacatagggcagcagcacca cctcgacttctgcccccattgcccacttgctatgggcctctcaaagtgggaggcacaaac cccagctgtggtcatcctgaggtgggcaggctaggagggggtcctgccttgtaccctcct cccgaaggacaggtatgtaaccccctggactctcttgatcttgacaacactcagctggac tttgtggctattctggatgagccccaggggctgagtcctcctccttcccatgatcagcgg ggcagctctggacataccccacctccctctgggccccccaacatggctgtgggcaacatg agtgtcttactgagatccctacctggggaaacagaattcctcaactctagtgcctaa |
Protein Sequence |
>2735 : length: 978 MSPSLGFPAQMNHQKGPSPSFGVQPCGPHDSARGGMIPHPQSRGPFPTCQLKSELDMLVG KCREEPLEGDMSSPNSTGIQDPLLGMLDGREDLEREEKREPESVYETDCRWDGCSQEFDS QEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGC RKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPG CTKRYTDPSSLRKHVKTVHGPDAHVTKRHRGDGPLPRAPSISTVEPKREREGGPIREESR LTVPEGAMKPQPSPGAQSSCSSDHSPAGSAANTDSGVEMTGNAGGSTEDLSSLDEGPCIA GTGLSTLRRLENLRLDQLHQLRPIGTRGLKLPSLSHTGTTVSRRVGPPVSLERRSSSSSS ISSAYTVSRRSSLASPFPPGSPPENGASSLPGLMPAQHYLLRARYASARGGGTSPTAASS LDRIGGLPMPPWRSRAEYPGYNPNAGVTRRASDPAQAADRPAPARVQRFKSLGCVHTPPT VAGGGQNFDPYLPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSGLNPYMDFPPTD TLGYGGPEGAAAEPYGARGPGSLPLGPGPPTNYGPNPCPQQASYPDPTQETWGEFPSHSG LYPGPKALGGTYSQCPRLEHYGQVQVKPEQGCPVGSDSTGLAPCLNAHPSEGPPHPQPLF SHYPQPSPPQYLQSGPYTQPPPDYLPSEPRPCLDFDSPTHSTGQLKAQLVCNYVQSQQEL LWEGGGREDAPAQEPSYQSPKFLGGSQVSPSRAKAPVNTYGPGFGPNLPNHKSGSYPTPS PCHENFVVGANRASHRAAAPPRLLPPLPTCYGPLKVGGTNPSCGHPEVGRLGGGPALYPP PEGQVCNPLDSLDLDNTQLDFVAILDEPQGLSPPPSHDQRGSSGHTPPPSGPPNMAVGNM SVLLRSLPGETEFLNSSA |