Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

2735

Name

GLI1

Synonymous

GLI;GLI family zinc finger 1;GLI1;GLI family zinc finger 1

Definition

GLI-Kruppel family member GLI1|glioma-associated oncogene 1|glioma-associated oncogene homolog 1 (zinc finger protein)|oncogene GLI|zinc finger protein GLI1

Position

12q13.2-q13.3

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

GLI(h) + Su(fu)(h) <==> GLI(h):Su(fu)(h) (binding)
Zic1(m) + GLI(h) <==> GLI(h):Zic1(m) (binding)
zic2(m) + GLI(h) <==> GLI(h):zic2(m) (binding)
GLI(h) + Fu(h) <==> GLI(h):Fu(h) (binding)
GLI(h) --> PTCH1(h) (DNA binding; transactivation).
GLI(h) --> MIRN29B1(h) (DNA binding).
GLI(h) --> MIRN29A(h) (DNA binding).
GLI1(h) --> GLI(h) (expression).
GLI(h) --> HNF-3beta(m) (DNA binding).
GLI(h) --> CCND2(h) (DNA binding).
GLI(h) --> JUP(h) (DNA binding).
GLI(h) --> GLI1(h) (DNA binding).
GLI(h) --> IGFBP6(h) (DNA binding).
GLI(h) --> SPP1(r) (DNA binding).
GLI(h) --> Spp1(m) (DNA binding).
GLI(h) --> BCL2(h) (DNA binding; transactivation).
GLI(h) --> IGFBP6(r) (DNA binding).
GLI(h) --> PTCH1(h) (DNA binding; transactivation).
GLI(h) --> KRT15(h) (transactivation)
GLI(h) --> KRT19(h) (transactivation)
GLI(h) --> PTCH1(h) (transactivation)
GLI(h) --> GAS1(h) (transactivation)
GLI1(h) --> GLI(h) (expression).

Post Transcriptional Modification   [Top]

There is no record for GLI1

Methylation Profile   [Top]

Chromosome

Location

Source

chr12

Promoter: 56138701 - 56140701Agilent_014791

chr12

Promoter: 56138701 - 56140701GSE27584


')