General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
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Gene ID | 27429 |
Name | HTRA2 |
Synonym | OMI|PARK13|PRSS25;HtrA serine peptidase 2;HTRA2;HtrA serine peptidase 2 |
Definition | HtrA-like serine protease|Omi stress-regulated endoprotease|high temperature requirement protein A2|protease, serine, 25|serine protease 25|serine protease HTRA2, mitochondrial|serine proteinase OMI |
Position | 2p12 |
Gene Type | protein-coding |
TSG scores |
Description |
TUSON ranking | 8679 |
TUSON P-value | 1 |
Pathways and Diseases |
|
Pathway | Parkinson's disease;KEGG PATHWAY;hsa05012 |
Disease | Parkinson's disease;KEGG DISEASE;H00057 |
Disease | Renal Cell cancer;FunDO |
Disease | Nervous system diseases;KEGG DISEASE |
Disease | Parkinson disease;FunDO |
Disease | Neurodegenerative diseases;KEGG DISEASE |
Disease | Parkinson disease 13;OMIM |
Disease | Colon cancer;FunDO |
Disease | Common wart;FunDO |
External Links |
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Links to Entrez Gene | 27429 |
Links to all GeneRIF Items | 27429 |
Links to iHOP | 27429 |
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>27429 : length: 1377 atggctgcgccgagggcggggcggggtgcaggctggagccttcgggcatggcgggctttg gggggcattcgctgggggaggagaccccgtttgacccctgacctccgggccctgctgacg tcaggaacttctgacccccgggcccgagtgacttatgggacccccagtctctgggcccgg ttgtctgttggggtcactgaaccccgagcatgcctgacgtctgggaccccgggtccccgg gcacaactgactgcggtgaccccagataccaggacccgggaggcctcagagaactctgga acccgttcgcgcgcgtggctggcggtggcgctgggcgctgggggggcagtgctgttgttg ttgtggggcgggggtcggggtcctccggccgtcctcgccgccgtccctagcccgccgccc gcttctccccggagtcagtacaacttcatcgcagatgtggtggagaagacagcacctgcc gtggtctatatcgagatcctggaccggcaccctttcttgggccgcgaggtccctatctcg aacggctcaggattcgtggtggctgccgatgggctcattgtcaccaacgcccatgtggtg gctgatcggcgcagagtccgtgtgagactgctaagcggcgacacgtatgaggccgtggtc acagctgtggatcccgtggcagacatcgcaacgctgaggattcagactaaggagcctctc cccacgctgcctctgggacgctcagctgatgtccggcaaggggagtttgttgttgccatg ggaagtccctttgcactgcagaacacgatcacatccggcattgttagctctgctcagcgt ccagccagagacctgggactcccccaaaccaatgtggaatacattcaaactgatgcagct attgattttggaaactctggaggtcccctggttaacctggatggggaggtgattggagtg aacaccatgaaggtcacagctggaatctcctttgccatcccttctgatcgtcttcgagag tttctgcatcgtggggaaaagaagaattcctcctccggaatcagtgggtcccagcggcgc tacattggggtgatgatgctgaccctgagtcccagcatccttgctgaactacagcttcga gaaccaagctttcccgatgttcagcatggtgtactcatccataaagtcatcctgggctcc cctgcacaccgggctggtctgcggcctggtgatgtgattttggccattggggagcagatg gtacaaaatgctgaagatgtttatgaagctgttcgaacccaatcccagttggcagtgcag atccggcggggacgagaaacactgaccttatatgtgacccctgaggtcacagaatga |
Protein Sequence |
>27429 : length: 458 MAAPRAGRGAGWSLRAWRALGGIRWGRRPRLTPDLRALLTSGTSDPRARVTYGTPSLWAR LSVGVTEPRACLTSGTPGPRAQLTAVTPDTRTREASENSGTRSRAWLAVALGAGGAVLLL LWGGGRGPPAVLAAVPSPPPASPRSQYNFIADVVEKTAPAVVYIEILDRHPFLGREVPIS NGSGFVVAADGLIVTNAHVVADRRRVRVRLLSGDTYEAVVTAVDPVADIATLRIQTKEPL PTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAA IDFGNSGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSSSGISGSQRR YIGVMMLTLSPSILAELQLREPSFPDVQHGVLIHKVILGSPAHRAGLRPGDVILAIGEQM VQNAEDVYEAVRTQSQLAVQIRRGRETLTLYVTPEVTE |