| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 29760 |
Name | BLNK |
Synonym | AGM4|BASH|BLNK-S|LY57|SLP-65|SLP65|bca;B-cell linker;BLNK;B-cell linker |
Definition | B cell adaptor containing SH2 domain|B cell linker protein|B-cell activation|B-cell adapter containing a SH2 domain protein|B-cell adapter containing a Src homology 2 domain protein|B-cell linker protein|Src homology 2 domain-containing leukocyte protein |
Position | 10q23.2-q23.33 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 3493 |
TUSON P-value | 1 |
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Pathways and Diseases |
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Pathway | BCR signaling pathway;PID Curated;200005 |
Pathway | Signaling in Immune system;Reactome;REACT:6900 |
Pathway | B cell receptor signaling pathway;KEGG PATHWAY;hsa04662 |
Pathway | B cell activation;PANTHER;P00010 |
Pathway | bcr signaling pathway;PID BioCarta;100227 |
Pathway | Primary immunodeficiency;KEGG PATHWAY;hsa05340 |
Disease | Primary immunodeficiency;KEGG DISEASE |
Disease | Immune system diseases;KEGG DISEASE |
Disease | Agammaglobulinemia 4;OMIM |
Disease | Agammaglobulinemias;KEGG DISEASE;H00085 |
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External Links |
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Links to Entrez Gene | 29760 |
Links to all GeneRIF Items | 29760 |
Links to iHOP | 29760 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>29760 : length: 1302 atggacaagcttaataaaataaccgtccccgccagtcagaagttgaggcagcttcaaaag atggtccatgatattaaaaacaatgaaggtggaataatgaataaaatcaaaaagctaaaa gtcaaagcacctccaagtgttcctcgaagggactacgcttcagagagccctgctgacgaa gaggagcagtggtccgatgactttgacagcgactatgaaaatccagatgagcactcggac tcagagatgtacgtgatgcccgccgaggagaacgctgatgacagctacgagccgcctcca gtagagcaggaaaccaggccggttcacccagccctgcccttcgccagaggcgagtatata gacaatcgatcaagccagaggcattccccacccttcagcaagacacttcccagtaagccc agctggccttcagagaaagcaaggctcacctccaccctgccggccctgactgctttgcag aaacctcaagtcccacccaaacccaaaggcctccttgaggatgaggctgattatgtggtc cccgtggaagataatgatgaaaactatattcatcccacagaaagcagttcacctccacct gaaaaaggtcgaaacagtggggcctgggaaaccaagtcacctccaccagctgcaccatcc ccgttgccacgggccgggaaaaaaccaacgacaccactgaagacaactccagttgcctct caacagaatgcttcaagtgtttgtgaagaaaaacctatacctgctgaacgccaccgaggg tcaagtcacagacaagaagctgtgcagtcaccagtgtttcctcctgcccagaaacaaatc caccaaaaacccatacctctgccaagatttacagaagggggaaacccaactgtggatggg cccctacccagcttttcatctaattccactatttcagaacaggaagctggcgttctctgc aagccatggtatgctggagcctgtgatcgaaagtctgctgaagaggcattgcacagatca aacaaggatggatcatttcttattcggaaaagctctggccatgattccaaacaaccatat acactagttgtattctttaataagcgagtatataatattcctgtgcgatttattgaagca acaaaacaatatgccttgggcagaaagaaaaatggtgaagagtactttggaagtgttgct gaaatcatcaggaatcatcaacatagtcctttggttcttattgacagtcagaataacaca aaagattccaccagactgaagtatgcagttaaagtttcataa |
Protein Sequence |
>29760 : length: 433 MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADE EEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYI DNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVV PVEDNDENYIHPTESSSPPPEKGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVAS QQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTVDG PLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPY TLVVFFNKRVYNIPVRFIEATKQYALGRKKNGEEYFGSVAEIIRNHQHSPLVLIDSQNNT KDSTRLKYAVKVS |