| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 29760 |
Name | BLNK |
Synonymous | AGM4|BASH|BLNK-S|LY57|SLP-65|SLP65|bca;B-cell linker;BLNK;B-cell linker |
Definition | B cell adaptor containing SH2 domain|B cell linker protein|B-cell activation|B-cell adapter containing a SH2 domain protein|B-cell adapter containing a Src homology 2 domain protein|B-cell linker protein|Src homology 2 domain-containing leukocyte protein |
Position | 10q23.2-q23.33 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
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Transcription Factors [Top] |
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Regulation From TransFac database |
ErbB2(h){pY1221} + BLNK(h) <==> ErbB2(h){pY1221}:BLNK(h) (binding) | ErbB4(h) + BLNK(h) <==> ErbB4(h):BLNK(h) (binding) | BLNK(h) + ATP --> BLNK(h){p} + ADP (phosphorylation) | BLNK(h) --> BLNK(h) (expression). | BLNK-isoform1(h) + ATP --Syk(m.s.)--> BLNK-isoform1(h){pY} + ADP (phosphorylation) | BLNK(h) --> BLNK-isoform1(h) (expression). | BLNK(h) --> BLNK-isoform2(h) (expression). |
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Post Transcriptional Modification [Top] | |||
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Location (AA) |
PTM type |
Literature |
Database |
72 | Phosphotyrosine. | Swiss-Prot 53.0 | 84 | Phosphotyrosine. | Swiss-Prot 53.0 | 96 | Phosphotyrosine. | Swiss-Prot 53.0 | 178 | Phosphotyrosine. | Swiss-Prot 53.0 | 189 | Phosphotyrosine. | Swiss-Prot 53.0 | 72 | Phosphotyrosine (Syk) | 12456653 | Phospho.ELM 6.0 | 84 | Phosphotyrosine (Syk) | 12456653 | Phospho.ELM 6.0 | 96 | Phosphotyrosine (Syk) | 12456653 | Phospho.ELM 6.0 | 178 | Phosphotyrosine (Syk) | 12456653;9697839 | Phospho.ELM 6.0 | 189 | Phosphotyrosine | 12456653 | Phospho.ELM 6.0 |
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Methylation Profile [Top] | ||
There is no record for BLNK | ||