Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

3627

Name

CXCL10

Synonym

C7|IFI10|INP10|IP-10|SCYB10|crg-2|gIP-10|mob-1;chemokine (C-X-C motif) ligand 10;CXCL10;chemokine (C-X-C motif) ligand 10

Definition

10 kDa interferon gamma-induced protein|C-X-C motif chemokine 10|gamma IP10|gamma-IP10|interferon-inducible cytokine IP-10|protein 10 from interferon (gamma)-induced cell line|small inducible cytokine subfamily B (Cys-X-Cys), member 10|small-inducible cyt

Position

4q21

Gene Type

protein-coding

TSG scores

Description

TUSON ranking

5561

TUSON P-value

1

Pathways and Diseases

Pathway

Toll-like receptor signaling pathway;KEGG PATHWAY;hsa04620

Pathway

Signaling by GPCR;Reactome;REACT:14797

Pathway

Cytokine-cytokine receptor interaction;KEGG PATHWAY;hsa04060

Pathway

RIG-I-like receptor signaling pathway;KEGG PATHWAY;hsa04622

Pathway

Chemokine signaling pathway;KEGG PATHWAY;hsa04062

Pathway

Cytosolic DNA-sensing pathway;KEGG PATHWAY;hsa04623

Pathway

Inflammation mediated by chemokine and cytokine signaling pathway;PANTHER;P00031

Pathway

CXCR3-mediated signaling events;PID Curated;200150

Disease

Autoimmune disease;FunDO

Disease

Primary biliary cirrhosis;FunDO

Disease

Hypothyroidism;FunDO

Disease

Pre-Eclampsia;FunDO

Disease

Pancreatitis;FunDO

Disease

Chronic rejection of renal transplant;FunDO

Disease

Infection;FunDO

Disease

Prostate cancer;FunDO

Disease

Uterine cancer;FunDO

Disease

Asthma;FunDO

Disease

Ulcerative colitis;FunDO

Disease

Thyroid gland disease;FunDO

Disease

Liver disease;FunDO

Disease

Systemic infection;FunDO

Disease

Hepatitis C;FunDO

Disease

Chronic obstructive airway disease;FunDO

Disease

Atherosclerosis;FunDO

External Links

Links to Entrez Gene

3627

Links to all GeneRIF Items

3627

Links to iHOP

3627

Sequence Information

The sequences provided here are only the longest representative sequences, not covering all the isoforms.

Nucleotide Sequence

>3627 : length: 297
atgaatcaaactgccattctgatttgctgccttatctttctgactctaagtggcattcaa
ggagtacctctctctagaactgtacgctgtacctgcatcagcattagtaatcaacctgtt
aatccaaggtctttagaaaaacttgaaattattcctgcaagccaattttgtccacgtgtt
gagatcattgctacaatgaaaaagaagggtgagaagagatgtctgaatccagaatcgaag
gccatcaagaatttactgaaagcagttagcaaggaaaggtctaaaagatctccttaa

Protein Sequence

>3627 : length: 98
MNQTAILICCLIFLTLSGIQGVPLSRTVRCTCISISNQPVNPRSLEKLEIIPASQFCPRV
EIIATMKKKGEKRCLNPESKAIKNLLKAVSKERSKRSP



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