| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 3659 |
Name | IRF1 |
Synonym | IRF-1|MAR;interferon regulatory factor 1;IRF1;interferon regulatory factor 1 |
Definition | interferon regulatory factor 1 isoform +I9|interferon regulatory factor 1 isoform d78|interferon regulatory factor 1 isoform delta4|interferon regulatory factor 1 isoform delta7 |
Position | 5q31.1 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 1352 |
TUSON P-value | 0.078666229 |
|
Pathways and Diseases |
|
Pathway | Glucocorticoid receptor regulatory network;PID Curated;200077 |
Pathway | IL6-mediated signaling events;PID Curated;200124 |
Pathway | IL12 signaling mediated by STAT4;PID Curated;200197 |
Pathway | Hepatitis C;KEGG PATHWAY;hsa05160 |
Pathway | the information processing pathway at the ifn beta enhancer;PID BioCarta;100079 |
Pathway | IFN-gamma pathway;PID Curated;200110 |
Disease | Gastric cancer, somatic;OMIM |
Disease | Nonsmall cell lung cancer, somatic;OMIM |
Disease | Mycobacterium infection, Atypical;FunDO |
Disease | HEMATOLOGICAL;GAD |
Disease | Bladder cancer;FunDO |
Disease | Asthma;FunDO |
Disease | Hepatitis C;FunDO |
Disease | Breast cancer;FunDO |
Disease | Embryoma;FunDO |
Disease | hepatitis C;GAD |
Disease | IMMUNE;GAD |
Disease | Infection;FunDO |
Disease | Asthma;GAD |
Disease | Systemic infection;FunDO |
Disease | INFECTION;GAD |
Disease | Cervical cancer;FunDO |
Disease | Myelogenous leukemia, acute;OMIM |
Disease | Multiple sclerosis;FunDO |
Disease | Endometrial cancer;FunDO |
Disease | Myelodysplastic syndrome, preleukemic;OMIM |
Disease | Fibrinogen;NHGRI |
Disease | Hepatitis C, Chronic;GAD |
Disease | Graves' disease;FunDO |
Disease | Behcet syndrome;FunDO |
Disease | Celiac disease;FunDO |
Disease | fibrinogen;GAD |
|
External Links |
|
Links to Entrez Gene | 3659 |
Links to all GeneRIF Items | 3659 |
Links to iHOP | 3659 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>3659 : length: 978 atgcccatcactcggatgcgcatgagaccctggctagagatgcagattaattccaaccaa atcccggggctcatctggattaataaagaggagatgatcttccagatcccatggaagcat gctgccaagcatggctgggacatcaacaaggatgcctgtttgttccggagctgggccatt cacacaggccgatacaaagcaggggaaaaggagccagatcccaagacgtggaaggccaac tttcgctgtgccatgaactccctgccagatatcgaggaggtgaaagaccagagcaggaac aagggcagctcagctgtgcgagtgtaccggatgcttccacctctcaccaagaaccagaga aaagaaagaaagtcgaagtccagccgagatgctaagagcaaggccaagaggaagtcatgt ggggattccagccctgataccttctctgatggactcagcagctccactctgcctgatgac cacagcagctacacagttccaggctacatgcaggacttggaggtggagcaggccctgact ccagcactgtcgccatgtgctgtcagcagcactctccccgactggcacatcccagtggaa gttgtgccggacagcaccagtgatctgtacaacttccaggtgtcacccatgccctccacc tctgaagctacaacagatgaggatgaggaagggaaattacctgaggacatcatgaagctc ttggagcagtcggagtggcagccaacaaacgtggatgggaaggggtacctactcaatgaa cctggagtccagcccacctctgtctatggagactttagctgtaaggaggagccagaaatt gacagcccagggggggatattgggctgagtctacagcgtgtcttcacagatctgaagaac atggatgccacctggctggacagcctgctgaccccagtccggttgccctccatccaggcc attccctgtgcaccgtag |
Protein Sequence |
>3659 : length: 325 MPITRMRMRPWLEMQINSNQIPGLIWINKEEMIFQIPWKHAAKHGWDINKDACLFRSWAI HTGRYKAGEKEPDPKTWKANFRCAMNSLPDIEEVKDQSRNKGSSAVRVYRMLPPLTKNQR KERKSKSSRDAKSKAKRKSCGDSSPDTFSDGLSSSTLPDDHSSYTVPGYMQDLEVEQALT PALSPCAVSSTLPDWHIPVEVVPDSTSDLYNFQVSPMPSTSEATTDEDEEGKLPEDIMKL LEQSEWQPTNVDGKGYLLNEPGVQPTSVYGDFSCKEEPEIDSPGGDIGLSLQRVFTDLKN MDATWLDSLLTPVRLPSIQAIPCAP |