| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 3659 |
Name | IRF1 |
Synonymous | IRF-1|MAR;interferon regulatory factor 1;IRF1;interferon regulatory factor 1 |
Definition | interferon regulatory factor 1 isoform +I9|interferon regulatory factor 1 isoform d78|interferon regulatory factor 1 isoform delta4|interferon regulatory factor 1 isoform delta7 |
Position | 5q31.1 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
 |
Transcription Factors [Top] |
|
Regulation From TransFac database |
irf1(h) --> H-2Kb(m) (DNA binding). | irf1(h) --> GBP(h) (DNA binding). | irf1(h) --> HNF-3beta(r) (DNA binding). | irf1(h) --> FasL(h) (DNA binding). | irf1(h) --> CIITA(h) (DNA binding; transactivation). | irf1(h) --> CYBB(h) (DNA binding; transactivation). | irf1(h) --> IL18BP(h) (DNA binding; transactivation). | irf1(h) --> CCL5(h) (DNA binding). | irf1(h) --> IFITM1(h) (DNA binding). | irf1(h) --> HLA-G(h) (DNA binding; transactivation). | irf1(h) + STAT1(h) <==> irf1(h):STAT1(h) (binding) | irf1(h) --> ISG15(h) (DNA binding). | irf1(h) --> COL1A2(h) (DNA binding). | irf1(h) --> CASP8(h) (DNA binding; transactivation). | irf1(h) --> NOD1(h) (DNA binding; transactivation). | irf1(h) --> PSMB9(h) (DNA binding). | irf1(h) --> TLR3(h) (DNA binding). | irf1(h) --> NR3C1(h) (DNA binding). | irf1(h) --> CCL19(h) (DNA binding; transactivation). | irf1(h) --> INDO(h) (DNA binding). | irf1(h) --> IL10(h) (DNA binding). | irf1(h) --> Tap1(h) (DNA binding). | irf1(h) --> CTSS(h) (DNA binding). | irf1(h) --> ISG20(h) (DNA binding). | irf1(h) --> VCAM1(h) (DNA binding). | irf1(h) --> IL-4(h) (DNA binding). | irf1(h) --> FOXP3(h) (DNA binding). | irf1(h) --/ OGN(h) (DNA binding; transrepression). | irf1(h) --> TRAF3IP2(h) (DNA binding). | irf1(h) --> IL7(h) (DNA binding; transactivation). | irf1(h) --> MYH9(h) (DNA binding). | irf1(h) --> PSMB10(h) (DNA binding). | irf1(h) --> IL27(h) (DNA binding). | irf1(h) --> MMP9(h) (DNA binding). | irf1(h) --> IL21R(h) (DNA binding). | irf1(h) --> STAT1(h) (DNA binding). | irf1(h) --> UPK2(h) (DNA binding). | irf1(h) --> IL28B(h) (DNA binding). | irf1(h) --> IL29(h) (DNA binding). | irf1(h) --> Pdgfd(h) (DNA binding). | IRF1(h) --> irf1(h) (expression). | CD154(h) --> irf1(h) (increase of abundance) | TNF-alpha(h) --> irf1(h) (increase of abundance) | IFNgamma(h) --> irf1(h) (increase of abundance) | IFNalpha2b(h) --> irf1(h) (increase of abundance) | irf1(h) --> IFNA1(h) (DNA binding; transregulation) | irf1(h) --> IFNB1(h) (DNA binding; transactivation). | irf1(h) --> ISG15(h) (DNA binding). | irf1(h) --> IFIT2(h) (DNA binding). | irf1(h) --> SLPI(h) (DNA binding; transregulation). | irf1(h) --> CMYBI1T(h) (DNA binding; transregulation). | irf1(h) --> IFNA4(m) (DNA binding; transactivation). | irf1(h) + p/CAF(h) <==> irf1(h):p/CAF(h) (binding) | irf1(h) --> NR3C1(h) (DNA binding; transactivation). | irf1(h) --> HPV-16(HPV16) (DNA binding; transactivation). | irf1(h) --> VCAM1(h) (DNA binding; transactivation). | irf1(h) --> CEACAM1(h) (DNA binding). | irf1(h) --> CIITA(h) (DNA binding; transactivation) | irf1(h) --> Myd88(m) (DNA binding). | irf1(h) --> IL12B(h) (DNA binding). | irf1(h) --> CCL19(h) (transactivation) | irf1(h) --> IL7(h) (transactivation) | irf1(h) --> GBP(h) (DNA binding). | irf1(h) --> MMP9(h) (DNA binding). | irf1(h) --> Nos2(m) (DNA binding). | irf1(h) --> IFNA4(h) (transactivation) | irf1(h) --> IL29(h) (transactivation) | irf1(h) --> IL28B(h) (transactivation) | irf1(h) --/ OGN(h) (transrepression) | irf1(h) --/ OGN(b) (transrepression) | irf1(h) --> GBP1(h) (DNA binding). | irf1(h) --> Pdgfd(h) (DNA binding). | IRF1(h) --> irf1(h) (expression). | IRF1(h) --> IRF1(h) (expression). | hsa-miR-203 --/ IRF1(h) (predicted) |
|---|
Post Transcriptional Modification [Top] | |||
There is no record for IRF1 | |||
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr5 |
Promoter: 131853826 - 131855826 | Agilent_014791 |
chr5 |
Promoter: 131853826 - 131855826 | GSE27584 |
chr5 |
Promoter: 131853826 - 131855826 | Agilent_014791_44K |