| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 3662 |
Name | IRF4 |
Synonym | LSIRF|MUM1|NF-EM5|SHEP8;interferon regulatory factor 4;IRF4;interferon regulatory factor 4 |
Definition | lymphocyte-specific interferon regulatory factor|multiple myeloma oncogene 1 |
Position | 6p25-p23 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 9028 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Calcineurin-regulated NFAT-dependent transcription in lymphocytes;PID Curated;200039 |
Pathway | IL4-mediated signaling events;PID Curated;200018 |
Disease | Eye color;NHGRI |
Disease | IMMUNE;GAD |
Disease | Bone marrow disease;FunDO |
Disease | Celiac disease;NHGRI |
Disease | Hair color;NHGRI |
Disease | Freckling;NHGRI |
Disease | HIV;GAD |
Disease | Multiple myeloma;OMIM |
Disease | Celiac Disease;GAD |
Disease | Melanoma;FunDO |
Disease | Chronic lymphocytic leukemia;GAD |
Disease | Black vs blond hair color;GAD |
Disease | Black vs. red hair color;NHGRI |
Disease | Leukemia;FunDO |
Disease | CANCER;GAD |
Disease | freckles;GAD |
Disease | INFECTION;GAD |
Disease | DEVELOPMENTAL;GAD |
Disease | Black vs red hair color;GAD |
Disease | Black vs. blond hair color;NHGRI |
Disease | Chronic lymphocytic leukemia;NHGRI |
|
External Links |
|
Links to Entrez Gene | 3662 |
Links to all GeneRIF Items | 3662 |
Links to iHOP | 3662 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>3662 : length: 1353 atgaacctggagggcggcggccgaggcggagagttcggcatgagcgcggtgagctgcggc aacgggaagctccgccagtggctgatcgaccagatcgacagcggcaagtaccccgggctg gtgtgggagaacgaggagaagagcatcttccgcatcccctggaagcacgcgggcaagcag gactacaaccgcgaggaggacgccgcgctcttcaaggcttgggcactgtttaaaggaaag ttccgagaaggcatcgacaagccggaccctcccacctggaagacgcgcctgcggtgcgct ttgaacaagagcaatgactttgaggaactggttgagcggagccagctggacatctcagac ccgtacaaagtgtacaggattgttcctgagggagccaaaaaaggagccaagcagctcacc ctggaggacccgcagatgtccatgagccacccctacaccatgacaacgccttacccttcg ctcccagcccaggttcacaactacatgatgccacccctcgaccgaagctggagggactac gtcccggatcagccacacccggaaatcccgtaccaatgtcccatgacgtttggaccccgc ggccaccactggcaaggcccagcttgtgaaaatggttgccaggtgacaggaaccttttat gcttgtgccccacctgagtcccaggctcccggagtccccacagagccaagcataaggtct gccgaagccttggcgttctcagactgccggctgcacatctgcctgtactaccgggaaatc ctcgtgaaggagctgaccacgtccagccccgagggctgccggatctcccatggacatacg tatgacgccagcaacctggaccaggtcctgttcccctacccagaggacaatggccagagg aaaaacattgagaagctgctgagccacctggagaggggcgtggtcctctggatggccccc gacgggctctatgcgaaaagactgtgccagagcaggatctactgggacgggcccctggcg ctgtgcaacgaccggcccaacaaactggagagagaccagacctgcaagctctttgacaca cagcagttcttgtcagagctgcaagcgtttgctcaccacggccgctccctgccaagattc caggtgactctatgctttggagaggagtttccagaccctcagaggcaaagaaagctcatc acagctcacgtagaacctctgctagccagacaactatattattttgctcaacaaaacagt ggacatttcctgaggggctacgatttaccagaacacatcagcaatccagaagattaccac agatctatccgccattcctctattcaagaatga |
Protein Sequence |
>3662 : length: 450 MNLEGGGRGGEFGMSAVSCGNGKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQ DYNREEDAALFKAWALFKGKFREGIDKPDPPTWKTRLRCALNKSNDFEELVERSQLDISD PYKVYRIVPEGAKKGAKQLTLEDPQMSMSHPYTMTTPYPSLPAQVHNYMMPPLDRSWRDY VPDQPHPEIPYQCPMTFGPRGHHWQGPACENGCQVTGTFYACAPPESQAPGVPTEPSIRS AEALAFSDCRLHICLYYREILVKELTTSSPEGCRISHGHTYDASNLDQVLFPYPEDNGQR KNIEKLLSHLERGVVLWMAPDGLYAKRLCQSRIYWDGPLALCNDRPNKLERDQTCKLFDT QQFLSELQAFAHHGRSLPRFQVTLCFGEEFPDPQRQRKLITAHVEPLLARQLYYFAQQNS GHFLRGYDLPEHISNPEDYHRSIRHSSIQE |