Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

3663

Name

IRF5

Synonym

SLEB10;interferon regulatory factor 5;IRF5;interferon regulatory factor 5

Definition

-

Position

7q32

Gene Type

protein-coding

TSG scores

Description

TUSON ranking

9029

TUSON P-value

1

Pathways and Diseases

Pathway

Toll-like receptor signaling pathway;KEGG PATHWAY;hsa04620

Pathway

Direct p53 effectors;PID Curated;200101

Disease

Autoimmune disease;FunDO

Disease

Lupus erythematosus;FunDO

Disease

Systemic lupus erythematosus, susceptibility to, 10;OMIM

Disease

Primary biliary cirrhosis;NHGRI

Disease

Systemic lupus erythematosus;NHGRI

Disease

IMMUNE;GAD

Disease

lupus erythematosus;GAD

Disease

Arthritis, Rheumatoid;GAD

Disease

Rheumatoid arthritis;NHGRI

Disease

Inflammatory bowel disease 14, susceptibility to;OMIM

Disease

Wegener's granulomatosis- reduced risk;GAD

Disease

rheumatoid arthritis;GAD

Disease

systemic lupus erythematosus;GAD

External Links

Links to Entrez Gene

3663

Links to all GeneRIF Items

3663

Links to iHOP

3663

Sequence Information

The sequences provided here are only the longest representative sequences, not covering all the isoforms.

Nucleotide Sequence

>3663 : length: 1497
atgaaccagtccatcccagtggctcccaccccaccccgccgcgtgcggctgaagccctgg
ctggtggcccaggtgaacagctgccagtacccagggcttcaatgggtcaacggggaaaag
aaattattctgcatcccctggaggcatgccacaaggcatggtcccagccaggacggagat
aacaccatcttcaaggcctgggccaaggagacagggaaatacaccgaaggcgtggatgaa
gccgatccggccaagtggaaggccaacctgcgctgtgcccttaacaagagccgggacttc
cgcctcatctacgacgggccccgggacatgccacctcagccctacaagatctacgaggtc
tgctccaatggccctgctcccacagactcccagccccctgaggattactcttttggtgca
ggagaggaggaggaagaagaggaagagctgcagaggatgttgccaagcctgagcctcaca
gaggatgtcaagtggccgcccactctgcagccgcccactctgcggccgcctactctgcag
ccgcccactctgcagccgcccgtggtgctgggtccccctgctccagaccccagccccctg
gctcctccccctggcaaccctgctggcttcagggagcttctctctgaggtcctggagcct
gggcccctgcctgccagcctgccccctgcaggcgaacagctcctgccagacctgctgatc
agcccccacatgctgcctctgaccgacctggagatcaagtttcagtaccgggggcggcca
ccccgggccctcaccatcagcaacccccatggctgccggctcttctacagccagctggag
gccacccaggagcaggtggaactcttcggccccataagcctggagcaagtgcgcttcccc
agccctgaggacatccccagtgacaagcagcgcttctacacgaaccagctgctggatgtc
ctggaccgcgggctcatcctccagctacagggccaggacctttatgccatccgcctgtgt
cagtgcaaggtgttctggagcgggccttgtgcctcagcccatgactcatgccccaacccc
atccagcgggaggtcaagaccaagcttttcagcctggagcattttctcaatgagctcatc
ctgttccaaaagggccagaccaacaccccaccacccttcgagatcttcttctgctttggg
gaagaatggcctgaccgcaaaccccgagagaagaagctcattactgtacaggtggtgcct
gtagcagctcgactgctgctggagatgttctcaggggagctatcttggtcagctgatagt
atccggctacagatctcaaacccagacctcaaagaccgcatggtggagcaattcaaggag
ctccatcacatctggcagtcccagcagcggttgcagcctgtggcccaggcccctcctgga
gcaggccttggtgttggccaggggccctggcctatgcacccagctggcatgcaataa

Protein Sequence

>3663 : length: 498
MNQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGD
NTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEV
CSNGPAPTDSQPPEDYSFGAGEEEEEEEELQRMLPSLSLTEDVKWPPTLQPPTLRPPTLQ
PPTLQPPVVLGPPAPDPSPLAPPPGNPAGFRELLSEVLEPGPLPASLPPAGEQLLPDLLI
SPHMLPLTDLEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQEQVELFGPISLEQVRFP
SPEDIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCASAHDSCPNP
IQREVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLITVQVVP
VAARLLLEMFSGELSWSADSIRLQISNPDLKDRMVEQFKELHHIWQSQQRLQPVAQAPPG
AGLGVGQGPWPMHPAGMQ



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