Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

3663

Name

IRF5

Synonymous

SLEB10;interferon regulatory factor 5;IRF5;interferon regulatory factor 5

Definition

-

Position

7q32

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

IRF-3(h) + IRF-5(h) <==> IRF-3(h):IRF-5(h) (binding).
IRF-5(h) --> CCL19(h) (DNA binding).
IRF5(h) --> IRF-5(h) (expression).
IRF-5(h) --> IFNA1(h) (DNA binding; transactivation).
IRF-5(h) --> IFNA14(h) (DNA binding; transactivation).
IRF-5(h) --> ISG15(h) (transactivation)
IRF-5(h) --> IRF-5(h) (translocation)
IRF-5(h) --> IFNA4(h) (transactivation)
IRF-5(h) --> IL29(h) (transactivation)
IRF-5(h) --> IL28B(h) (transactivation)
IRF5(h) --> IRF-5(h) (expression).
IRF-5(h) --> IRF-5(h) (translocation)
IRF5(h) --> IRF-5-xbb2(h) (expression).
IRF-5-xbb3(h) + n ubiquitin(h) --> IRF-5-xbb3(h){ub}n (ubiquitination)
IRF5(h) --> IRF-5-xbb3(h) (expression).
IRF-5-xbb4(h) + n ubiquitin(h) --> IRF-5-xbb4(h){ub}n (ubiquitination)
IRF-5-xbb4(h) + TRAF6(m.s.) <==> IRF-5-xbb4(h):TRAF6(m.s.) (binding)
IRF5(h) --> IRF-5-xbb4(h) (expression).
IRF5(h) --> IRF-5-xbb5(h) (expression).
IRF5(h) --> IRF-5-xbb6(h) (expression).
IRF5(h) --> IRF-5-xbb7(h) (expression).
IRF5(h) --> IRF-5-xbb1(h) (expression).

Post Transcriptional Modification   [Top]

There is no record for IRF5

Methylation Profile   [Top]

Chromosome

Location

Source

chr7

Promoter: 128363730 - 128365730Agilent_014791

chr7

Promoter: 128364007 - 128366007Agilent_014791

chr7

Promoter: 128363730 - 128365730GoldenGate_Methylation_Cancer_Panel_I

chr7

Promoter: 128364007 - 128366007GoldenGate_Methylation_Cancer_Panel_I

chr7

Promoter: 128364007 - 128366007GSE27584

chr7

Promoter: 128363730 - 128365730GSE27584

chr7

Promoter: 128363730 - 128365730Agilent_014791_44K


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