Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

388

Name

RHOB

Synonym

ARH6|ARHB|MST081|MSTP081|RHOH6;ras homolog family member B;RHOB;ras homolog family member B

Definition

Aplysia RAS-related homolog 6|h6|oncogene RHO H6|ras homolog gene family, member B|rho cDNA clone 6|rho-related GTP-binding protein RhoB

Position

2p24

Gene Type

protein-coding

TSG scores

Description

TUSON ranking

14081

TUSON P-value

1

Pathways and Diseases

Pathway

Axon guidance;Reactome;REACT:18266

Pathway

Hemostasis;Reactome;REACT:604

Pathway

Axon guidance mediated by Slit/Robo;PANTHER;P00008

Pathway

Signaling by GPCR;Reactome;REACT:14797

Pathway

PDGF signaling pathway;PANTHER;P00047

Pathway

Signaling by Rho GTPases;Reactome;REACT:11044

Pathway

Angiogenesis;PANTHER;P00005

Pathway

Integrin signalling pathway;PANTHER;P00034

Pathway

Ras Pathway;PANTHER;P04393

Pathway

Cytoskeletal regulation by Rho GTPase;PANTHER;P00016

Disease

Cancer;FunDO

Disease

Polyarthritis;FunDO

External Links

Links to Entrez Gene

388

Links to all GeneRIF Items

388

Links to iHOP

388

Sequence Information

The sequences provided here are only the longest representative sequences, not covering all the isoforms.

Nucleotide Sequence

>388 : length: 591
atggcggccatccgcaagaagctggtggtggtgggcgacggcgcgtgtggcaagacgtgc
ctgctgatcgtgttcagtaaggacgagttccccgaggtgtacgtgcccaccgtcttcgag
aactatgtggccgacattgaggtggacggcaagcaggtggagctggcgctgtgggacacg
gcgggccaggaggactacgaccgcctgcggccgctctcctacccggacaccgacgtcatt
ctcatgtgcttctcggtggacagcccggactcgctggagaacatccccgagaagtgggtc
cccgaggtgaagcacttctgtcccaatgtgcccatcatcctggtggccaacaaaaaagac
ctgcgcagcgacgagcatgtccgcacagagctggcccgcatgaagcaggaacccgtgcgc
acggatgacggccgcgccatggccgtgcgcatccaagcctacgactacctcgagtgctct
gccaagaccaaggaaggcgtgcgcgaggtcttcgagacggccacgcgcgccgcgctgcag
aagcgctacggctcccagaacggctgcatcaactgctgcaaggtgctatga

Protein Sequence

>388 : length: 196
MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDT
AGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKD
LRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQ
KRYGSQNGCINCCKVL



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