| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 3977 |
Name | LIFR |
Synonym | CD118|LIF-R|SJS2|STWS|SWS;leukemia inhibitory factor receptor alpha;LIFR;leukemia inhibitory factor receptor alpha |
Definition | CD118 antigen|LIF receptor|leukemia inhibitory factor receptor |
Position | 5p13-p12 |
Gene Type | protein-coding |
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TSG scores |
Description |
| TUSON ranking | 1186 |
TUSON P-value | 0.059745371 |
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Pathways and Diseases |
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Pathway | Jak-STAT signaling pathway;KEGG PATHWAY;hsa04630 |
Pathway | Cytokine-cytokine receptor interaction;KEGG PATHWAY;hsa04060 |
Disease | Pancreas cancer;FunDO |
Disease | Stuve-Wiedemann syndrome/Schwartz-Jampel type 2 syndrome;OMIM |
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External Links |
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Links to Entrez Gene | 3977 |
Links to all GeneRIF Items | 3977 |
Links to iHOP | 3977 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>3977 : length: 3294 atgatggatatttacgtatgtttgaaacgaccatcctggatggtggacaataaaagaatg aggactgcttcaaatttccagtggctgttatcaacatttattcttctatatctaatgaat caagtaaatagccagaaaaagggggctcctcatgatttgaagtgtgtaactaacaatttg caagtgtggaactgttcttggaaagcaccctctggaacaggccgtggtactgattatgaa gtttgcattgaaaacaggtcccgttcttgttatcagttggagaaaaccagtattaaaatt ccagctctttcacatggtgattatgaaataacaataaattctctacatgattttggaagt tctacaagtaaattcacactaaatgaacaaaacgtttccttaattccagatactccagag atcttgaatttgtctgctgatttctcaacctctacattatacctaaagtggaacgacagg ggttcagtttttccacaccgctcaaatgttatctgggaaattaaagttctacgtaaagag agtatggagctcgtaaaattagtgacccacaacacaactctgaatggcaaagatacactt catcactggagttgggcctcagatatgcccttggaatgtgccattcattttgtggaaatt agatgctacattgacaatcttcatttttctggtctcgaagagtggagtgactggagccct gtgaagaacatttcttggatacctgattctcagactaaggtttttcctcaagataaagtg atacttgtaggctcagacataacattttgttgtgtgagtcaagaaaaagtgttatcagca ctgattggccatacaaactgccccttgatccatcttgatggggaaaatgttgcaatcaag attcgtaatatttctgtttctgcaagtagtggaacaaatgtagtttttacaaccgaagat aacatatttggaaccgttatttttgctggatatccaccagatactcctcaacaactgaat tgtgagacacatgatttaaaagaaattatatgtagttggaatccaggaagggtgacagcg ttggtgggcccacgtgctacaagctacactttagttgaaagtttttcaggaaaatatgtt agacttaaaagagctgaagcacctacaaacgaaagctatcaattattatttcaaatgctt ccaaatcaagaaatatataattttactttgaatgctcacaatccgctgggtcgatcacaa tcaacaattttagttaatataactgaaaaagtttatccccatactcctacttcattcaaa gtgaaggatattaattcaacagctgttaaactttcttggcatttaccaggcaactttgca aagattaattttttatgtgaaattgaaattaagaaatctaattcagtacaagagcagcgg aatgtcacaatcaaaggagtagaaaattcaagttatcttgttgctctggacaagttaaat ccatacactctatatacttttcggattcgttgttctactgaaactttctggaaatggagc aaatggagcaataaaaaacaacatttaacaacagaagccagtccttcaaaggggcctgat acttggagagagtggagttctgatggaaaaaatttaataatctattggaagcctttaccc attaatgaagctaatggaaaaatactttcctacaatgtatcgtgttcatcagatgaggaa acacagtccctttctgaaatccctgatcctcagcacaaagcagagatacgacttgataag aatgactacatcatcagcgtagtggctaaaaattctgtgggctcatcaccaccttccaaa atagcgagtatggaaattccaaatgatgatctcaaaatagaacaagttgttgggatggga aaggggattctcctcacctggcattacgaccccaacatgacttgcgactacgtcattaag tggtgtaactcgtctcggtcggaaccatgccttatggactggagaaaagttccctcaaac agcactgaaactgtaatagaatctgatgagtttcgaccaggtataagatataattttttc ctgtatggatgcagaaatcaaggatatcaattattacgctccatgattggatatatagaa gaattggctcccattgttgcaccaaattttactgttgaggatacttctgcagattcgata ttagtaaaatgggaagacattcctgtggaagaacttagaggctttttaagaggatatttg ttttactttggaaaaggagaaagagacacatctaagatgagggttttagaatcaggtcgt tctgacataaaagttaagaatattactgacatatcccagaagacactgagaattgctgat cttcaaggtaaaacaagttaccacctggtcttgcgagcctatacagatggtggagtgggc ccggagaagagtatgtatgtggtgacaaaggaaaattctgtgggattaattattgccatt ctcatcccagtggcagtggctgtcattgttggagtggtgacaagtatcctttgctatcgg aaacgagaatggattaaagaaaccttctaccctgatattccaaatccagaaaactgtaaa gcattacagtttcaaaagagtgtctgtgagggaagcagtgctcttaaaacattggaaatg aatccttgtaccccaaataatgttgaggttctggaaactcgatcagcatttcctaaaata gaagatacagaaataatttccccagtagctgagcgtcctgaagatcgctctgatgcagag cctgaaaaccatgtggttgtgtcctattgtccacccatcattgaggaagaaataccaaac ccagccgcagatgaagctggagggactgcacaggttatttacattgatgttcagtcgatg tatcagcctcaagcaaaaccagaagaagaacaagaaaatgaccctgtaggaggggcaggc tataagccacagatgcacctccccattaattctactgtggaagatatagctgcagaagag gacttagataaaactgcgggttacagacctcaggccaatgtaaatacatggaatttagtg tctccagactctcctagatccatagacagcaacagtgagattgtctcatttggaagtcca tgctccattaattcccgacaatttttgattcctcctaaagatgaagactctcctaaatct aatggaggagggtggtcctttacaaacttttttcagaacaaaccaaacgattaa |
Protein Sequence |
>3977 : length: 1097 MMDIYVCLKRPSWMVDNKRMRTASNFQWLLSTFILLYLMNQVNSQKKGAPHDLKCVTNNL QVWNCSWKAPSGTGRGTDYEVCIENRSRSCYQLEKTSIKIPALSHGDYEITINSLHDFGS STSKFTLNEQNVSLIPDTPEILNLSADFSTSTLYLKWNDRGSVFPHRSNVIWEIKVLRKE SMELVKLVTHNTTLNGKDTLHHWSWASDMPLECAIHFVEIRCYIDNLHFSGLEEWSDWSP VKNISWIPDSQTKVFPQDKVILVGSDITFCCVSQEKVLSALIGHTNCPLIHLDGENVAIK IRNISVSASSGTNVVFTTEDNIFGTVIFAGYPPDTPQQLNCETHDLKEIICSWNPGRVTA LVGPRATSYTLVESFSGKYVRLKRAEAPTNESYQLLFQMLPNQEIYNFTLNAHNPLGRSQ STILVNITEKVYPHTPTSFKVKDINSTAVKLSWHLPGNFAKINFLCEIEIKKSNSVQEQR NVTIKGVENSSYLVALDKLNPYTLYTFRIRCSTETFWKWSKWSNKKQHLTTEASPSKGPD TWREWSSDGKNLIIYWKPLPINEANGKILSYNVSCSSDEETQSLSEIPDPQHKAEIRLDK NDYIISVVAKNSVGSSPPSKIASMEIPNDDLKIEQVVGMGKGILLTWHYDPNMTCDYVIK WCNSSRSEPCLMDWRKVPSNSTETVIESDEFRPGIRYNFFLYGCRNQGYQLLRSMIGYIE ELAPIVAPNFTVEDTSADSILVKWEDIPVEELRGFLRGYLFYFGKGERDTSKMRVLESGR SDIKVKNITDISQKTLRIADLQGKTSYHLVLRAYTDGGVGPEKSMYVVTKENSVGLIIAI LIPVAVAVIVGVVTSILCYRKREWIKETFYPDIPNPENCKALQFQKSVCEGSSALKTLEM NPCTPNNVEVLETRSAFPKIEDTEIISPVAERPEDRSDAEPENHVVVSYCPPIIEEEIPN PAADEAGGTAQVIYIDVQSMYQPQAKPEEEQENDPVGGAGYKPQMHLPINSTVEDIAAEE DLDKTAGYRPQANVNTWNLVSPDSPRSIDSNSEIVSFGSPCSINSRQFLIPPKDEDSPKS NGGGWSFTNFFQNKPND |