| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 3977 |
Name | LIFR |
Synonymous | CD118|LIF-R|SJS2|STWS|SWS;leukemia inhibitory factor receptor alpha;LIFR;leukemia inhibitory factor receptor alpha |
Definition | CD118 antigen|LIF receptor|leukemia inhibitory factor receptor |
Position | 5p13-p12 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
 |
Transcription Factors [Top] |
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Regulation From TransFac database |
LIFR(h) + ATP --ERK1(m)--> LIFR(h){p} + ADP (phosphorylation) | LIFR(h) + ATP --ERK2(m)--> LIFR(h){p} + ADP (phosphorylation) | LIFR(h) + ATP --ERK2(v.s.)--> LIFR(h){pS1044} + ADP (phosphorylation) | LIFR(h) --> CNTF(m.s.) (activation) | LIFR(h) + ATP --> LIFR(h){pY} + ADP (phosphorylation) | gp130(h) + LIFR(h) <==> gp130(h):LIFR(h) (binding) | CNTFR(h) + LIFR(h) <==> CNTFR(h):LIFR(h) (binding) | LIFR(h) --> LIFR(h) (expression). | LIFR(h) + gp130-isoform1(h) <==> LIFR(h):gp130-isoform1(h) (binding) | LIFR(h) --> LIFR(h) (expression). |
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Post Transcriptional Modification [Top] | |||
|
Location (AA) |
PTM type |
Literature |
Database |
64 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 85 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 131 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 143 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 191 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 243 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 303 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 390 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 407 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 426 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 445 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 481 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 489 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 572 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 652 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 663 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 680 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 729 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 787 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 1044 | Phosphoserine (MAPK1;MAPK3;) | 7777512 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
There is no record for LIFR | ||