Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

5320

Name

PLA2G2A

Synonym

MOM1|PLA2|PLA2B|PLA2L|PLA2S|PLAS1|sPLA2;phospholipase A2, group IIA (platelets, synovial fluid);PLA2G2A;phospholipase A2, group IIA (platelets, synovial fluid)

Definition

GIIC sPLA2|NPS-PLA2|group IIA phospholipase A2|non-pancreatic secretory phospholipase A2|phosphatidylcholine 2-acylhydrolase 2A|phospholipase A2, membrane associated

Position

1p35

Gene Type

protein-coding

TSG scores

Description

TUSON ranking

12868

TUSON P-value

1

Pathways and Diseases

Pathway

Vascular smooth muscle contraction;KEGG PATHWAY;hsa04270

Pathway

VEGF signaling pathway;KEGG PATHWAY;hsa04370

Pathway

Fc epsilon RI signaling pathway;KEGG PATHWAY;hsa04664

Pathway

Pancreatic secretion;KEGG PATHWAY;hsa04972

Pathway

Toxoplasmosis;KEGG PATHWAY;hsa05145

Pathway

Glypican 1 network;PID Curated;200021

Pathway

phospholipases;BioCyc;LIPASYN-PWY

Pathway

MAPK signaling pathway;KEGG PATHWAY;hsa04010

Pathway

Metabolic pathways;KEGG PATHWAY;hsa01100

Pathway

Glycerophospholipid metabolism;KEGG PATHWAY;hsa00564

Pathway

alpha-Linolenic acid metabolism;KEGG PATHWAY;hsa00592

Pathway

Long-term depression;KEGG PATHWAY;hsa04730

Pathway

Ether lipid metabolism;KEGG PATHWAY;hsa00565

Pathway

Linoleic acid metabolism;KEGG PATHWAY;hsa00591

Pathway

GnRH signaling pathway;KEGG PATHWAY;hsa04912

Pathway

Arachidonic acid metabolism;KEGG PATHWAY;hsa00590

Disease

Drug abuse;FunDO

Disease

Embryoma;FunDO

Disease

PSYCH;GAD

Disease

Diabetes mellitus;FunDO

Disease

Cystic fibrosis;FunDO

Disease

Vascular dementia;FunDO

Disease

Colorectal cancer;OMIM

Disease

Schizophrenia;FunDO

Disease

Dental plaque;FunDO

Disease

Cholelithiasis;FunDO

Disease

Stroke;FunDO

Disease

Stomach cancer;FunDO

Disease

Alzheimer's disease;FunDO

Disease

affective disorder;GAD

Disease

Neoplasm metastasis;FunDO

Disease

Atherosclerosis;FunDO

External Links

Links to Entrez Gene

5320

Links to all GeneRIF Items

5320

Links to iHOP

5320

Sequence Information

The sequences provided here are only the longest representative sequences, not covering all the isoforms.

Nucleotide Sequence

>5320 : length: 435
atgaagaccctcctactgttggcagtgatcatgatctttggcctactgcaggcccatggg
aatttggtgaatttccacagaatgatcaagttgacgacaggaaaggaagccgcactcagt
tatggcttctacggctgccactgtggcgtgggtggcagaggatcccccaaggatgcaacg
gatcgctgctgtgtcactcatgactgttgctacaaacgtctggagaaacgtggatgtggc
accaaatttctgagctacaagtttagcaactcggggagcagaatcacctgtgcaaaacag
gactcctgcagaagtcaactgtgtgagtgtgataaggctgctgccacctgttttgctaga
aacaagacgacctacaataaaaagtaccagtactattccaataaacactgcagagggagc
acccctcgttgctga

Protein Sequence

>5320 : length: 144
MKTLLLLAVIMIFGLLQAHGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDAT
DRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFAR
NKTTYNKKYQYYSNKHCRGSTPRC



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