| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 5333 |
Name | PLCD1 |
Synonym | NDNC3|PLC-III;phospholipase C, delta 1;PLCD1;phospholipase C, delta 1 |
Definition | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1|1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1|PLC-delta-1|phosphoinositide phospholipase C-delta-1|phospholipase C-III |
Position | 3p22-p21.3 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 12901 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | D-myo-inositol (1,4,5)-trisphosphate biosynthesis;BioCyc;PWY-6351 |
Pathway | D-myo-inositol-5-phosphate metabolism;BioCyc;PWY-6367 |
Pathway | Oxytocin receptor mediated signaling pathway;PANTHER;P04391 |
Pathway | Phosphatidylinositol signaling system;KEGG PATHWAY;hsa04070 |
Pathway | Histamine H1 receptor mediated signaling pathway;PANTHER;P04385 |
Pathway | phospholipases;BioCyc;LIPASYN-PWY |
Pathway | Inositol phosphate metabolism;KEGG PATHWAY;hsa00562 |
Pathway | Metabolic pathways;KEGG PATHWAY;hsa01100 |
Pathway | 5HT2 type receptor mediated signaling pathway;PANTHER;P04374 |
Pathway | phospholipase c delta in phospholipid associated cell signaling;PID BioCarta;100071 |
Pathway | Calcium signaling pathway;KEGG PATHWAY;hsa04020 |
Pathway | Thyrotropin-releasing hormone receptor signaling pathway;PANTHER;P04394 |
Pathway | Inflammation mediated by chemokine and cytokine signaling pathway;PANTHER;P00031 |
Disease | Breast cancer;FunDO |
Disease | Esophagus cancer;FunDO |
|
External Links |
|
Links to Entrez Gene | 5333 |
Links to all GeneRIF Items | 5333 |
Links to iHOP | 5333 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>5333 : length: 2334 atgcagtgcctggggatccggagccggagccgctccagggagctctacctgcaggagcgg agccttaaggtggcggcgctcaatggacggaggctgggcctacaggatgatgaggatcta caggcgctgctgaagggcagccagctcctgaaggtgaagtccagctcatggaggagagag cgcttctacaagttgcaggaggactgcaagaccatctggcaggagtcccgcaaggtcatg cggaccccggagtcccagctgttctccatcgaggacattcaggaggtgcgaatggggcac cgcacggagggtctggagaagttcgcccgtgatgtgcccgaggaccgctgcttctccatt gtcttcaaggaccagcgcaatacactagacctcatcgccccatcgccagctgatgcccag cactgggtgctggggctgcacaagatcatccaccactcaggctccatggaccagcgtcag aagctacagcactggattcactcctgcttgcgaaaagctgacaaaaacaaggacaacaag atgagcttcaaggagctgcagaacttcctgaaggagctcaacatccaggtggacgacagc tatgcccggaagatcttcagggagtgtgaccactcccagacagactccctggaggacgag gagattgaggccttctacaagatgctgacccagcgggtggagatcgaccgcaccttcgcc gaggccgcgggctcaggggagactctgtcggtggatcagttagtgacgttcctgcagcac cagcagcgggaggaggcggcagggcctgcgctggccctctccctcattgagcgctacgag cccagcgagactgccaaggcgcagcggcagatgaccaaggacggcttcctcatgtactta ctgtcggctgacggcagcgccttcagcctggcacaccgccgtgtctaccaggacatgggc cagccacttagccactacctggtgtcctcttcacacaacacctacctgctggaggaccag ctagccgggcccagcagcactgaagcctacatccgggcactgtgcaaaggctgccgatgc ctggagcttgactgctgggacgggcccaaccaggaaccaatcatctaccacggctatact ttcacttccaagatcctcttctgcgatgtgctcagggccatccgggactatgccttcaag gcgtccccctaccctgtcatcctatccctggagaaccactgcacactggagcagcagcgc gtgatggcgcggcacctgcatgccatcctgggccccatgctgttgaaccgaccactggat ggggtcaccaacagcctgccctcccctgagcaactgaaggggaagatcctgctgaagggg aagaagctcggggggctcctgccccctggaggggagggtggccctgaggccactgtggtg tcagacgaagacgaggctgctgagatggaggatgaggcagtgaggagccgtgtgcagcac aagcccaaggaggacaagctcaggctagcacaggagctctctgacatggtcatttactgc aagagtgtccactttgggggcttctccagtcctggcacccctggacaggccttctacgag atggcgtccttctctgagaaccgtgcccttcgactgctccaagaatcaggaaacggcttt gtccgccacaacgtggggcacctgagcagaatctacccggctggatggagaacagactcc tccaactacagccccgtggagatgtggaatgggggctgccagatcgtggccctgaatttc cagacacctgggccagagatggacgtgtaccagggccgcttccaggacaacggggcctgt gggtacgtgctgaagcccgccttcctgcgagaccccaacggcacctttaacccccgcgcc ctggctcaggggccctggtgggcacggaagcggctcaacatcagggtcatttcggggcag cagctgccaaaagtcaacaagaataagaattcaattgtggaccccaaagtgacagtggag atccatggcgtgagccgggacgtggccagccgccagactgctgtcatcaccaacaatggt ttcaacccatggtgggacacggagtttgcgtttgaggtagttgtgcctgaccttgccctc atccgcttcttggtggaagattatgatgcctcctccaagaatgacttcattggccagagt accatccccttgaacagcctcaagcaaggataccgccatgtccacctcatgtctaagaac ggggaccagcatccatcagccaccctctttgtgaagatctccctccaggactag |
Protein Sequence |
>5333 : length: 777 MQCLGIRSRSRSRELYLQERSLKVAALNGRRLGLQDDEDLQALLKGSQLLKVKSSSWRRE RFYKLQEDCKTIWQESRKVMRTPESQLFSIEDIQEVRMGHRTEGLEKFARDVPEDRCFSI VFKDQRNTLDLIAPSPADAQHWVLGLHKIIHHSGSMDQRQKLQHWIHSCLRKADKNKDNK MSFKELQNFLKELNIQVDDSYARKIFRECDHSQTDSLEDEEIEAFYKMLTQRVEIDRTFA EAAGSGETLSVDQLVTFLQHQQREEAAGPALALSLIERYEPSETAKAQRQMTKDGFLMYL LSADGSAFSLAHRRVYQDMGQPLSHYLVSSSHNTYLLEDQLAGPSSTEAYIRALCKGCRC LELDCWDGPNQEPIIYHGYTFTSKILFCDVLRAIRDYAFKASPYPVILSLENHCTLEQQR VMARHLHAILGPMLLNRPLDGVTNSLPSPEQLKGKILLKGKKLGGLLPPGGEGGPEATVV SDEDEAAEMEDEAVRSRVQHKPKEDKLRLAQELSDMVIYCKSVHFGGFSSPGTPGQAFYE MASFSENRALRLLQESGNGFVRHNVGHLSRIYPAGWRTDSSNYSPVEMWNGGCQIVALNF QTPGPEMDVYQGRFQDNGACGYVLKPAFLRDPNGTFNPRALAQGPWWARKRLNIRVISGQ QLPKVNKNKNSIVDPKVTVEIHGVSRDVASRQTAVITNNGFNPWWDTEFAFEVVVPDLAL IRFLVEDYDASSKNDFIGQSTIPLNSLKQGYRHVHLMSKNGDQHPSATLFVKISLQD |