Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

5333

Name

PLCD1

Synonymous

NDNC3|PLC-III;phospholipase C, delta 1;PLCD1;phospholipase C, delta 1

Definition

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1|1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1|PLC-delta-1|phosphoinositide phospholipase C-delta-1|phospholipase C-III

Position

3p22-p21.3

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

RalA(m.s.) + PLCdelta1(h) <==> RalA(m.s.):PLCdelta1(h) (binding)
ralB(m.s.) + PLCdelta1(h) <==> ralB(m.s.):PLCdelta1(h) (binding)
calmodulin(h) + PLCdelta1(m.s.) + Ral(h) + PLCdelta1(h) <==> calmodulin(h):PLCdelta1(h):PLCdelta1(m.s.):Ral(h) (binding)
PLCdelta1(m.s.) + PLCdelta1(h) <==> PLCdelta1(h):PLCdelta1(m.s.) (binding)
PLCD1(h) --> PLCdelta1(h) (expression).
PIP2 --PLCdelta1(h)--> IP3 + DAG (hydrolysis)
ralB(m.s.) + PLCdelta1(h) <==> ralB(m.s.):PLCdelta1(h) (binding)
PLCdelta1(h) + RalA(h) <==> PLCdelta1(h):RalA(h) (binding)
Ral(h) + PLCdelta1(h) + calmodulin(h) <==> Ral(h):PLCdelta1(h):calmodulin(h) (binding)
RalA(m.s.) + PLCdelta1(h) <==> RalA(m.s.):PLCdelta1(h) (binding)
PLCD1(h) --> PLCdelta1(h) (expression).

Post Transcriptional Modification   [Top]

There is no record for PLCD1

Methylation Profile   [Top]

Chromosome

Location

Source

chr3

Promoter: 38045637 - 38047637GSE27584

chr3

Promoter: 38045637 - 38047637Agilent_014791_44K


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