| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 5337 |
Name | PLD1 |
Synonym | -;phospholipase D1, phosphatidylcholine-specific;PLD1;phospholipase D1, phosphatidylcholine-specific |
Definition | choline phosphatase 1|phosphatidylcholine-hydrolyzing phospholipase D1|phospholipase D1 |
Position | 3q26 |
Gene Type | protein-coding |
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TSG scores |
Description |
| TUSON ranking | 12913 |
TUSON P-value | 1 |
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Pathways and Diseases |
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Pathway | Pancreatic cancer;KEGG PATHWAY;hsa05212 |
Pathway | Endocytosis;KEGG PATHWAY;hsa04144 |
Pathway | Fc gamma R-mediated phagocytosis;KEGG PATHWAY;hsa04666 |
Pathway | metabolism of anandamide an endogenous cannabinoid;PID BioCarta;100217 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | Angiogenesis;PANTHER;P00005 |
Pathway | phospholipases;BioCyc;LIPASYN-PWY |
Pathway | Metabolic pathways;KEGG PATHWAY;hsa01100 |
Pathway | Alpha-synuclein signaling;PID Curated;200187 |
Pathway | Glycerophospholipid metabolism;KEGG PATHWAY;hsa00564 |
Pathway | rac1 cell motility signaling pathway;PID BioCarta;100056 |
Pathway | ErbB1 downstream signaling;PID Curated;200113 |
Pathway | Ether lipid metabolism;KEGG PATHWAY;hsa00565 |
Pathway | choline biosynthesis III;BioCyc;PWY-3561 |
Pathway | Ras Pathway;PANTHER;P04393 |
Pathway | GnRH signaling pathway;KEGG PATHWAY;hsa04912 |
Pathway | ras signaling pathway;PID BioCarta;100047 |
Pathway | CDC42 signaling events;PID Curated;200057 |
Disease | Brain tumor;FunDO |
Disease | Melanoma;FunDO |
Disease | Breast cancer;FunDO |
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External Links |
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Links to Entrez Gene | 5337 |
Links to all GeneRIF Items | 5337 |
Links to iHOP | 5337 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>5337 : length: 3111 atgtcactgaaaaacgagccacgggtaaatacctctgcactgcagaaaattgctgctgac atgagtaatatcatagaaaatctggacacgcgggaactccactttgagggagaggaggta gactacgacgtgtctcccagcgatcccaagatacaagaagtgtatatccctttctctgct atttataacactcaaggatttaaggagcctaatatacagacgtatctctccggctgtcca ataaaagcacaagttctggaagtggaacgcttcacatctacaacaagggtaccaagtatt aatctttacactattgaattaacacatggggaatttaaatggcaagttaagaggaaattc aagcattttcaagaatttcacagagagctgctcaagtacaaagcctttatccgcatcccc attcccactagaagacacacgtttaggaggcaaaacgtcagagaggagcctcgagagatg cccagtttgccccgttcatctgaaaacatgataagagaagaacaattccttggtagaaga aaacaactggaagattacttgacaaagatactaaaaatgcccatgtatagaaactatcat gccacaacagagtttcttgatataagccagctgtctttcatccatgatttgggaccaaag ggcatagaaggtatgataatgaaaagatctggaggacacagaataccaggcttgaattgc tgtggtcagggaagagcctgctacagatggtcaaaaagatggttaatagtgaaagattcc tttttattgtatatgaaaccagacagcggtgccattgccttcgtcctgctggtagacaaa gaattcaaaattaaggtggggaagaaggagacagaaacgaaatatggaatccgaattgat aatctttcaaggacacttattttaaaatgcaacagctatagacatgctcggtggtgggga ggggctatagaagaattcatccagaaacatggcaccaactttctcaaagatcatcgattt gggtcatatgctgctatccaagagaatgctttagctaaatggtatgttaatgccaaagga tattttgaagatgtggcaaatgcaatggaagaggcaaatgaagagatttttatcacagac tggtggctgagtccagaaatcttcctgaaacgcccagtggttgagggaaatcgttggagg ttggactgcattcttaaacgaaaagcacaacaaggagtgaggatcttcataatgctctac aaagaggtggaactcgctcttggcatcaatagtgaatacaccaagaggactttgatgcgt ctacatcccaacataaaggtgatgagacacccggatcatgtgtcatccaccgtctatttg tgggctcaccatgagaagcttgtcatcattgaccaatcggtggcctttgtgggagggatt gacctggcctatggaaggtgggacgacaatgagcacagactcacagacgtgggcagtgtg aagcgggtcacttcaggaccgtctctgggttccctcccacctgccgcaatggagtctatg gaatccttaagactcaaagataaaaatgagcctgttcaaaacctacccatccagaagagt attgatgatgtggattcaaaactgaaaggaataggaaagccaagaaagttctccaaattt agtctctacaagcagctccacaggcaccacctgcacgacgcagatagcatcagcagcatt gacagcacctccaataccgggtccatccgtagtttacagacaggtgtgggagagctgcat ggggaaaccagattctggcatggaaaggactactgcaatttcgtcttcaaagactgggtt caacttgataaaccttttgctgatttcattgacaggtactccacgccccggatgccctgg catgacattgcctctgcagtccacgggaaggcggctcgtgatgtggcacgtcacttcatc cagcgctggaacttcacaaaaattatgaaatcaaaatatcggtccctttcttatcctttt ctgcttccaaagtctcaaacaacagcccatgagttgagatatcaagtgcctgggtctgtc catgctaacgtacagttgctccgctctgctgctgattggtctgctggtataaagtaccat gaagagtccatccacgccgcttacgtccatgtgatagagaacagcaggcactatatctat atcgaaaaccagtttttcataagctgtgctgatgacaaagttgtgttcaacaagataggc gatgccattgcccagaggatcctgaaagctcacagggaaaaccagaaataccgggtatat gtcgtgataccacttctgccagggttcgaaggagacatttcaaccggcggaggaaatgct ctacaggcaatcatgcacttcaactacagaaccatgtgcagaggagaaaattccatcctt ggacagttaaaagcagagcttggtaatcagtggataaattacatatcattctgtggtctt agaacacatgcagagctcgaaggaaacctagtaactgagcttatctatgtccacagcaag ttgttaattgctgatgataacactgttattattggctctgccaacataaatgaccgcagc atgctgggaaagcgtgacagtgaaatggctgtcattgtgcaagatacagagactgttcct tcagtaatggatggaaaagagtaccaagctggccggtttgcccgaggacttcggctacag tgctttagggttgtccttggctatcttgatgacccaagtgaggacattcaggatccagtg agtgacaaattcttcaaggaggtgtgggtttcaacagcagctcgaaatgctacaatttat gacaaggttttccggtgccttcccaatgatgaagtacacaatttaattcagctgagagac tttataaacaagcccgtattagctaaggaagatcccattcgagctgaggaggaactgaag aagatccgtggatttttggtgcaattccccttttatttcttgtctgaagaaagcctactg ccttctgttgggaccaaagaggccatagtgcccatggaggtttggacttaa |
Protein Sequence |
>5337 : length: 1036 MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFEGEEVDYDVSPSDPKIQEVYIPFSA IYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVREEPREMPSLPRSSENMIREEQFLGRR KQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRID NLSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKG YFEDVANAMEEANEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLY KEVELALGINSEYTKRTLMRLHPNIKVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGI DLAYGRWDDNEHRLTDVGSVKRVTSGPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKS IDDVDSKLKGIGKPRKFSKFSLYKQLHRHHLHDADSISSIDSTSNTGSIRSLQTGVGELH GETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYSTPRMPWHDIASAVHGKAARDVARHFI QRWNFTKIMKSKYRSLSYPFLLPKSQTTAHELRYQVPGSVHANVQLLRSAADWSAGIKYH EESIHAAYVHVIENSRHYIYIENQFFISCADDKVVFNKIGDAIAQRILKAHRENQKYRVY VVIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGL RTHAELEGNLVTELIYVHSKLLIADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVP SVMDGKEYQAGRFARGLRLQCFRVVLGYLDDPSEDIQDPVSDKFFKEVWVSTAARNATIY DKVFRCLPNDEVHNLIQLRDFINKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLL PSVGTKEAIVPMEVWT |