| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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Gene ID | 5337 |
Name | PLD1 |
Synonymous | -;phospholipase D1, phosphatidylcholine-specific;PLD1;phospholipase D1, phosphatidylcholine-specific |
Definition | choline phosphatase 1|phosphatidylcholine-hydrolyzing phospholipase D1|phospholipase D1 |
Position | 3q26 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
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Transcription Factors [Top] |
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Regulation From TransFac database |
RhoA(h):GTP + pld1a(h) <==> RhoA(h):GTP:pld1a(h) (binding) | PKCalpha(h) + pld1a(h) <==> PKCalpha(h):pld1a(h) (binding) | pld1a(h) + PKCalpha(h) <==> pld1a(h):PKCalpha(h) (binding) | ARF6(h) + pld1a(h) <==> ARF6(h):pld1a(h) (binding) | arf1(h):GTP --> pld1a(h) (activation) | Rac1(h):GTP --> pld1a(h) (activation) | PIP2 --> pld1a(h) (activation) | PIP3 --> pld1a(h) (activation) | Cdc42(h):GTP --> pld1a(h) (activation) | PLD1(h) --> pld1a(h) (expression). | Arih1(m) + pld1b(h) <==> Arih1(m):pld1b(h) (binding) | EWS(m) + pld1b(h) <==> EWS(m):pld1b(h) (binding) | PEA-15(m) + pld1b(h) <==> PEA-15(m):pld1b(h) (binding) | BRE1B(m) + pld1b(h) <==> BRE1B(m):pld1b(h) (binding) | PKCalpha(h) --> pld1b(h) (binding) | PIP2 --> pld1b(h) (activation) | PIP3 --> pld1b(h) (activation) | arf1(h):GTP --> pld1b(h) (activation) | RhoA(h):GTP --> pld1b(h) (activation) | Rac1(h):GTP --> pld1b(h) (activation) | Cdc42(h):GTP --> pld1b(h) (activation) | PLD1(h) --> pld1b(h) (expression). | pld1(h) + AP180(b) <==> pld1(h):AP180(b) (binding) | amphiphysin1(h) + pld1(h) <==> amphiphysin1(h):pld1(h) (binding) | amphiphysin2(m) + pld1(h) <==> amphiphysin2(m):pld1(h) (binding) | PEA-15(m) + pld1(h) <==> PEA-15(m):pld1(h) (binding) | RhoA(m.s.) + pld1(h) <==> RhoA(m.s.):pld1(h) (binding) | Cdc42(m.s.) + pld1(h) <==> Cdc42(m.s.):pld1(h) (binding) | PEA15(h) + pld1(h) <==> PEA15(h):pld1(h) (binding) | pld1(h) --> PKCalpha(r){pY657} (increase of phosphorylation) | PLD1(h) --> pld1(h) (expression). | FcgammaRI alpha(h) --> pld1(h) (activation) | PC --pld1(h)--> PA + choline (processing; hydrolysis) | PLD1(h) --> pld1-isoform3(h) (expression). | PLD1(h) --> pld1-isoform4(h) (expression). |
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Post Transcriptional Modification [Top] | |||
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Location (AA) |
PTM type |
Literature |
Database |
240 | S-palmitoyl cysteine (By similarity). | Swiss-Prot 53.0 | 241 | S-palmitoyl cysteine (By similarity). | Swiss-Prot 53.0 | 629 | Phosphoserine. | Swiss-Prot 53.0 | 629 | Phosphoserine | 17081983 | Phospho.ELM 6.0 |
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Methylation Profile [Top] | ||
There is no record for PLD1 | ||