Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

5499

Name

PPP1CA

Synonym

PP-1A|PP1A|PP1alpha|PPP1A;protein phosphatase 1, catalytic subunit, alpha isozyme;PPP1CA;protein phosphatase 1, catalytic subunit, alpha isozyme

Definition

protein phosphatase 1, catalytic subunit, alpha isoform|serine/threonine protein phosphatase PP1-alpha 1 catalytic subunit|serine/threonine-protein phosphatase PP1-alpha catalytic subunit

Position

11q13

Gene Type

protein-coding

TSG scores

Description

TUSON ranking

13195

TUSON P-value

1

Pathways and Diseases

Pathway

Vascular smooth muscle contraction;KEGG PATHWAY;hsa04270

Pathway

Insulin signaling pathway;KEGG PATHWAY;hsa04910

Pathway

TGF-beta receptor signaling;PID Curated;200195

Pathway

BMP receptor signaling;PID Curated;200123

Pathway

protein kinase a at the centrosome;PID BioCarta;100246

Pathway

Focal adhesion;KEGG PATHWAY;hsa04510

Pathway

Regulation of actin cytoskeleton;KEGG PATHWAY;hsa04810

Pathway

Long-term potentiation;KEGG PATHWAY;hsa04720

Pathway

ALK1 signaling events;PID Curated;200126

Pathway

DARPP-32 events;PID Reactome;500841

Pathway

Oocyte meiosis;KEGG PATHWAY;hsa04114

Pathway

regulation of ck1/cdk5 by type 1 glutamate receptors;PID BioCarta;100201

Pathway

Opioid Signalling;Reactome;REACT:15295

Pathway

Metabolism of lipids and lipoproteins;Reactome;REACT:22258

External Links

Links to Entrez Gene

5499

Links to all GeneRIF Items

5499

Links to iHOP

5499

Sequence Information

The sequences provided here are only the longest representative sequences, not covering all the isoforms.

Nucleotide Sequence

>5499 : length: 1026
atgtccgacagcgagaagctcaacctggactcgatcatcgggcgcctgctggaagggtcc
agggtcctgacaccccattgcgccccagtgcagggctcgcggcctggcaagaatgtacag
ctgacagagaacgagatccgcggtctgtgcctgaaatcccgggagatttttctgagccag
cccattcttctggagctggaggcacccctcaagatctgcggtgacatacacggccagtac
tacgaccttctgcgactatttgagtatggcggtttccctcccgagagcaactacctcttt
ctgggggactatgtggacaggggcaagcagtccttggagaccatctgcctgctgctggcc
tataagatcaagtaccccgagaacttcttcctgctccgtgggaaccacgagtgtgccagc
atcaaccgcatctatggtttctacgatgagtgcaagagacgctacaacatcaaactgtgg
aaaaccttcactgactgcttcaactgcctgcccatcgcggccatagtggacgaaaagatc
ttctgctgccacggaggcctgtccccggacctgcagtctatggagcagattcggcggatc
atgcggcccacagatgtgcctgaccagggcctgctgtgtgacctgctgtggtctgaccct
gacaaggacgtgcagggctggggcgagaacgaccgtggcgtctcttttacctttggagcc
gaggtggtggccaagttcctccacaagcacgacttggacctcatctgccgagcacaccag
gtggtagaagacggctacgagttctttgccaagcggcagctggtgacacttttctcagct
cccaactactgtggcgagtttgacaatgctggcgccatgatgagtgtggacgagaccctc
atgtgctctttccagatcctcaagcccgccgacaagaacaaggggaagtacgggcagttc
agtggcctgaaccctggaggccgacccatcaccccaccccgcaattccgccaaagccaag
aaatag

Protein Sequence

>5499 : length: 341
MSDSEKLNLDSIIGRLLEGSRVLTPHCAPVQGSRPGKNVQLTENEIRGLCLKSREIFLSQ
PILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLA
YKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKI
FCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGA
EVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETL
MCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK



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