| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 5499 |
Name | PPP1CA |
Synonym | PP-1A|PP1A|PP1alpha|PPP1A;protein phosphatase 1, catalytic subunit, alpha isozyme;PPP1CA;protein phosphatase 1, catalytic subunit, alpha isozyme |
Definition | protein phosphatase 1, catalytic subunit, alpha isoform|serine/threonine protein phosphatase PP1-alpha 1 catalytic subunit|serine/threonine-protein phosphatase PP1-alpha catalytic subunit |
Position | 11q13 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 13195 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Vascular smooth muscle contraction;KEGG PATHWAY;hsa04270 |
Pathway | Insulin signaling pathway;KEGG PATHWAY;hsa04910 |
Pathway | TGF-beta receptor signaling;PID Curated;200195 |
Pathway | BMP receptor signaling;PID Curated;200123 |
Pathway | protein kinase a at the centrosome;PID BioCarta;100246 |
Pathway | Focal adhesion;KEGG PATHWAY;hsa04510 |
Pathway | Regulation of actin cytoskeleton;KEGG PATHWAY;hsa04810 |
Pathway | Long-term potentiation;KEGG PATHWAY;hsa04720 |
Pathway | ALK1 signaling events;PID Curated;200126 |
Pathway | DARPP-32 events;PID Reactome;500841 |
Pathway | Oocyte meiosis;KEGG PATHWAY;hsa04114 |
Pathway | regulation of ck1/cdk5 by type 1 glutamate receptors;PID BioCarta;100201 |
Pathway | Opioid Signalling;Reactome;REACT:15295 |
Pathway | Metabolism of lipids and lipoproteins;Reactome;REACT:22258 |
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External Links |
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Links to Entrez Gene | 5499 |
Links to all GeneRIF Items | 5499 |
Links to iHOP | 5499 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>5499 : length: 1026 atgtccgacagcgagaagctcaacctggactcgatcatcgggcgcctgctggaagggtcc agggtcctgacaccccattgcgccccagtgcagggctcgcggcctggcaagaatgtacag ctgacagagaacgagatccgcggtctgtgcctgaaatcccgggagatttttctgagccag cccattcttctggagctggaggcacccctcaagatctgcggtgacatacacggccagtac tacgaccttctgcgactatttgagtatggcggtttccctcccgagagcaactacctcttt ctgggggactatgtggacaggggcaagcagtccttggagaccatctgcctgctgctggcc tataagatcaagtaccccgagaacttcttcctgctccgtgggaaccacgagtgtgccagc atcaaccgcatctatggtttctacgatgagtgcaagagacgctacaacatcaaactgtgg aaaaccttcactgactgcttcaactgcctgcccatcgcggccatagtggacgaaaagatc ttctgctgccacggaggcctgtccccggacctgcagtctatggagcagattcggcggatc atgcggcccacagatgtgcctgaccagggcctgctgtgtgacctgctgtggtctgaccct gacaaggacgtgcagggctggggcgagaacgaccgtggcgtctcttttacctttggagcc gaggtggtggccaagttcctccacaagcacgacttggacctcatctgccgagcacaccag gtggtagaagacggctacgagttctttgccaagcggcagctggtgacacttttctcagct cccaactactgtggcgagtttgacaatgctggcgccatgatgagtgtggacgagaccctc atgtgctctttccagatcctcaagcccgccgacaagaacaaggggaagtacgggcagttc agtggcctgaaccctggaggccgacccatcaccccaccccgcaattccgccaaagccaag aaatag |
Protein Sequence |
>5499 : length: 341 MSDSEKLNLDSIIGRLLEGSRVLTPHCAPVQGSRPGKNVQLTENEIRGLCLKSREIFLSQ PILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLA YKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKI FCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGA EVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETL MCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK |