| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 5562 |
Name | PRKAA1 |
Synonym | AMPK|AMPKa1;protein kinase, AMP-activated, alpha 1 catalytic subunit;PRKAA1;protein kinase, AMP-activated, alpha 1 catalytic subunit |
Definition | 5'-AMP-activated protein kinase catalytic subunit alpha-1|5'-AMP-activated protein kinase, catalytic alpha-1 chain|ACACA kinase|AMP -activate kinase alpha 1 subunit|AMP-activated protein kinase, catalytic, alpha-1|AMPK alpha 1|AMPK subunit alpha-1|HMGCR k |
Position | 5p12 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 13322 |
TUSON P-value | 1 |
|
Pathways and Diseases |
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Pathway | Adipocytokine signaling pathway;KEGG PATHWAY;hsa04920 |
Pathway | Insulin signaling pathway;KEGG PATHWAY;hsa04910 |
Pathway | Signaling by Insulin receptor;Reactome;REACT:498 |
Pathway | p53 pathway by glucose deprivation;PANTHER;P04397 |
Pathway | Activated AMPK stimulates fatty-acid oxidation in muscle;Reactome;REACT:11163 |
Pathway | Hypertrophic cardiomyopathy (HCM);KEGG PATHWAY;hsa05410 |
Pathway | Regulation of autophagy;KEGG PATHWAY;hsa04140 |
Pathway | mTOR signaling pathway;KEGG PATHWAY;hsa04150 |
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External Links |
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Links to Entrez Gene | 5562 |
Links to all GeneRIF Items | 5562 |
Links to iHOP | 5562 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>5562 : length: 1680 atgcgcagactcagttcctggagaaagatggcgacagccgagaagcagaaacacgacggg cgggtgaagatcggccactacattctgggtgacacgctgggggtcggcaccttcggcaaa gtgaaggttggcaaacatgaattgactgggcataaagtagctgtgaagatactcaatcga cagaagattcggagccttgatgtggtaggaaaaatccgcagagaaattcagaacctcaag cttttcaggcatcctcatataattaaactgtaccaggtcatcagtacaccatctgatatt ttcatggtgatggaatatgtctcaggaggagagctatttgattatatctgtaagaatgga aggctggatgaaaaagaaagtcggcgtctgttccaacagatcctttctggtgtggattat tgtcacaggcatatggtggtccatagagatttgaaacctgaaaatgtcctgcttgatgca cacatgaatgcaaagatagctgattttggtctttcaaacatgatgtcagatggtgaattt ttaagaacaagttgtggctcacccaactatgctgcaccagaagtaatttcaggaagattg tatgcaggcccagaggtagatatatggagcagtggggttattctctatgctttattatgt ggaacccttccatttgatgatgaccatgtgccaactctttttaagaagatatgtgatggg atcttctatacccctcaatatttaaatccttctgtgattagccttttgaaacatatgctg caggtggatcccatgaagagggccacaatcaaagatatcagggaacatgaatggtttaaa caggaccttccaaaatatctctttcctgaggatccatcatatagttcaaccatgattgat gatgaagccttaaaagaagtatgtgaaaagtttgagtgctcagaagaggaagttctcagc tgtctttacaacagaaatcaccaggatcctttggcagttgcctaccatctcataatagat aacaggagaataatgaatgaagccaaagatttctatttggcgacaagcccacctgattct tttcttgatgatcatcacctgactcggccccatcctgaaagagtaccattcttggttgct gaaacaccaagggcacgccatacccttgatgaattaaatccacagaaatccaaacaccaa ggtgtaaggaaagcaaaatggcatttaggaattagaagtcaaagtcgaccaaatgatatt atggcagaagtatgtagagcaatcaaacaattggattatgaatggaaggttgtaaaccca tattatttgcgtgtacgaaggaagaatcctgtgacaagcacttactccaaaatgagtcta cagttataccaagtggatagtagaacttatctactggatttccgtagtattgatgatgaa attacagaagccaaatcagggactgctactccacagagatcgggatcagttagcaactat cgatcttgccaaaggagtgattcagatgctgaggctcaaggaaaatcctcagaagtttct cttacctcatctgtgacctcacttgactcttctcctgttgacctaactccaagacctgga agtcacacaatagaattttttgagatgtgtgcaaatctaattaaaattcttgcacaataa |
Protein Sequence |
>5562 : length: 559 MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNR QKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNG RLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEF LRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDG IFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMID DEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPDS FLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDI MAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDE ITEAKSGTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSVTSLDSSPVDLTPRPG SHTIEFFEMCANLIKILAQ |