Entrez Gene

Basic Information
Gene ID	5562
Name	PRKAA1
Synonymous	AMPK\|AMPKa1;protein kinase, AMP-activated, alpha 1 catalytic subunit;PRKAA1;protein kinase, AMP-activated, alpha 1 catalytic subunit
Definition	5'-AMP-activated protein kinase catalytic subunit alpha-1\|5'-AMP-activated protein kinase, catalytic alpha-1 chain\|ACACA kinase\|AMP -activate kinase alpha 1 subunit\|AMP-activated protein kinase, catalytic, alpha-1\|AMPK alpha 1\|AMPK subunit alpha-1\|HMGCR k
Position	5p12
Gene Type	protein-coding
Gene Regulation:	Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase [Top]

Regulation From TransFac database
Transcription Factors [Top]
AMPKalpha-1(h) + ATP --> AMPKalpha-1(h){pT172} + ADP (phosphorylation)
PRKAA1(h) --> AMPKalpha-1(h) (expression).
AMPKalpha-1(h) --> eNOS(h){pS633} (increase of phosphorylation)
PRKAA1(h) --> AMPKalpha-1(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Transcriptional Modification [Top]
174	Phosphothreonine (by STK11) (Bysimilarity).		Swiss-Prot 53.0
175	Phosphoserine (By similarity).		Swiss-Prot 53.0
499	Phosphoserine (By similarity).		Swiss-Prot 53.0
487	Phosphoserine	16083285	Phospho.ELM 6.0