| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 5602 |
Name | MAPK10 |
Synonym | JNK3|JNK3A|PRKM10|SAPK1b|p493F12|p54bSAPK;mitogen-activated protein kinase 10;MAPK10;mitogen-activated protein kinase 10 |
Definition | JNK3 alpha protein kinase|MAP kinase 10|MAP kinase p49 3F12|MAPK 10|c-Jun N-terminal kinase 3|stress activated protein kinase beta|stress-activated protein kinase 1b|stress-activated protein kinase JNK3 |
Position | 4q22.1-q23 |
Gene Type | protein-coding |
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TSG scores |
Description |
| TUSON ranking | 10305 |
TUSON P-value | 1 |
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Pathways and Diseases |
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Pathway | Signaling in Immune system;Reactome;REACT:6900 |
Pathway | Glucocorticoid receptor regulatory network;PID Curated;200077 |
Pathway | Neurotrophin signaling pathway;KEGG PATHWAY;hsa04722 |
Pathway | RIG-I-like receptor signaling pathway;KEGG PATHWAY;hsa04622 |
Pathway | MAPK signaling pathway;KEGG PATHWAY;hsa04010 |
Pathway | Interferon-gamma signaling pathway;PANTHER;P00035 |
Pathway | TGF-beta signaling pathway;PANTHER;P00052 |
Pathway | Toxoplasmosis;KEGG PATHWAY;hsa05145 |
Pathway | FGF signaling pathway;PANTHER;P00021 |
Pathway | p75(NTR)-mediated signaling;PID Curated;200103 |
Pathway | Pancreatic cancer;KEGG PATHWAY;hsa05212 |
Pathway | Wnt signaling pathway;KEGG PATHWAY;hsa04310 |
Pathway | Focal adhesion;KEGG PATHWAY;hsa04510 |
Pathway | GnRH signaling pathway;KEGG PATHWAY;hsa04912 |
Pathway | NOD-like receptor signaling pathway;KEGG PATHWAY;hsa04621 |
Pathway | PDGF signaling pathway;PANTHER;P00047 |
Pathway | Apoptosis signaling pathway;PANTHER;P00006 |
Pathway | Shigellosis;KEGG PATHWAY;hsa05131 |
Pathway | EGF receptor signaling pathway;PANTHER;P00018 |
Pathway | CD40/CD40L signaling;PID Curated;200031 |
Pathway | Hepatitis C;KEGG PATHWAY;hsa05160 |
Pathway | FAS signaling pathway;PANTHER;P00020 |
Pathway | Colorectal cancer;KEGG PATHWAY;hsa05210 |
Pathway | Adipocytokine signaling pathway;KEGG PATHWAY;hsa04920 |
Pathway | ErbB2/ErbB3 signaling events;PID Curated;200119 |
Pathway | Insulin signaling pathway;KEGG PATHWAY;hsa04910 |
Pathway | Parkinson disease;PANTHER;P00049 |
Pathway | B cell activation;PANTHER;P00010 |
Pathway | ErbB signaling pathway;KEGG PATHWAY;hsa04012 |
Pathway | Progesterone-mediated oocyte maturation;KEGG PATHWAY;hsa04914 |
Pathway | Epithelial cell signaling in Helicobacter pylori infection;KEGG PATHWAY;hsa05120 |
Pathway | Noncanonical Wnt signaling pathway;PID Curated;200016 |
Pathway | Integrin signalling pathway;PANTHER;P00034 |
Pathway | Protein processing in endoplasmic reticulum;KEGG PATHWAY;hsa04141 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | Ras Pathway;PANTHER;P04393 |
Pathway | Alzheimer disease-amyloid secretase pathway;PANTHER;P00003 |
Pathway | Chagas disease;KEGG PATHWAY;hsa05142 |
Pathway | Fc epsilon RI signaling pathway;KEGG PATHWAY;hsa04664 |
Pathway | Toll-like receptor signaling pathway;KEGG PATHWAY;hsa04620 |
Pathway | FAS (CD95) signaling pathway;PID Curated;200067 |
Pathway | mapkinase signaling pathway;PID BioCarta;100113 |
Pathway | Oxidative stress response;PANTHER;P00046 |
Pathway | FoxO family signaling;PID Curated;200091 |
Pathway | Type II diabetes mellitus;KEGG PATHWAY;hsa04930 |
Disease | Epileptic encephalopathy, Lennox-Gastaut type;OMIM |
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External Links |
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Links to Entrez Gene | 5602 |
Links to all GeneRIF Items | 5602 |
Links to iHOP | 5602 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>5602 : length: 1269 atgagcctccatttcttatactactgcagtgaaccaacattggatgtgaaaattgccttt tgtcagggattcgataaacaagtggatgtgtcatatattgccaaacattacaacatgagc aaaagcaaagttgacaaccagttctacagtgtggaagtgggagactcaaccttcacagtt ctcaagcgctaccagaatctaaagcctattggctctggggctcagggcatagtttgtgcc gcgtatgatgctgtccttgacagaaatgtggccattaagaagctcagcagaccctttcag aaccaaacacatgccaagagagcgtaccgggagctggtcctcatgaagtgtgtgaaccat aaaaacattattagtttattaaatgtcttcacaccccagaaaacgctggaggagttccaa gatgtttacttagtaatggaactgatggatgccaacttatgtcaagtgattcagatggaa ttagaccatgagcgaatgtcttacctgctgtaccaaatgttgtgtggcattaagcacctc cattctgctggaattattcacagggatttaaaaccaagtaacattgtagtcaagtctgat tgcacattgaaaatcctggactttggactggccaggacagcaggcacaagcttcatgatg actccatatgtggtgacacgttattacagagcccctgaggtcatcctggggatgggctac aaggagaacgtggatatatggtctgtgggatgcattatgggagaaatggttcgccacaaa atcctctttccaggaagggactatattgaccagtggaataaggtaattgaacaactagga acaccatgtccagaattcatgaagaaattgcaacccacagtaagaaactatgtggagaat cggcccaagtatgcgggactcaccttccccaaactcttcccagattccctcttcccagcg gactccgagcacaataaactcaaagccagccaagccagggacttgttgtcaaagatgcta gtgattgacccagcaaaaagaatatcagtggacgacgccttacagcatccctacatcaac gtctggtatgacccagccgaagtggaggcgcctccacctcagatatatgacaagcagttg gatgaaagagaacacacaattgaagaatggaaagaacttatctacaaggaagtaatgaat tcagaagaaaagactaaaaatggtgtagtaaaaggacagccttctccttcagcacaggtg cagcagtga |
Protein Sequence |
>5602 : length: 422 MSLHFLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTV LKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH KNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHL HSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY KENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVEN RPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYIN VWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSAQV QQ |