| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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Gene ID | 5602 |
Name | MAPK10 |
Synonymous | JNK3|JNK3A|PRKM10|SAPK1b|p493F12|p54bSAPK;mitogen-activated protein kinase 10;MAPK10;mitogen-activated protein kinase 10 |
Definition | JNK3 alpha protein kinase|MAP kinase 10|MAP kinase p49 3F12|MAPK 10|c-Jun N-terminal kinase 3|stress activated protein kinase beta|stress-activated protein kinase 1b|stress-activated protein kinase JNK3 |
Position | 4q22.1-q23 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
There is no record for MAPK10 | |||
Transcription Factors [Top] |
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Regulation From TransFac database |
JNK3alpha1(h) + p53(m) <==> JNK3alpha1(h):p53(m) (binding) | MAPK10(h) --> JNK3alpha1(h) (expression). | beta-arrestin2(h) + JNK3(h) <==> beta-arrestin2(h):JNK3(h) (binding) | beta-arrestin2(h) + ASK1(v.s.) + MKK4(v.s.) + JNK3(h) <==> beta-arrestin2(h):ASK1(v.s.):MKK4(v.s.):JNK3(h) (binding) | NR1B1(m) + JNK3(h) <==> NR1B1(m):JNK3(h) (binding) | JNK3(h) + ATP --> JNK3(h){pY} + ADP (phosphorylation) | JNK3(h) + ATP --> JNK3(h){p} + ADP (phosphorylation) | JNK3(h) + TF3C-alpha(h) <==> JNK3(h):TF3C-alpha(h) (binding) | JNK3(h) + RG4(h) <==> JNK3(h):RG4(h) (binding) | MAPK10(h) --> JNK3(h) (expression). | c-Myc(h) + 2 ATP --JNK3(h)--> c-Myc(h){pS62}{pS71} + 2 ADP (phosphorylation) | MAPK10(h) --> JNK3alpha2(h) (expression). | MAPK10(h) --> JNK3beta(h) (expression). | MAPK10(h) --> JNK3 isoform 4(h) (expression). |
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Post Transcriptional Modification [Top] | |||
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Location (AA) |
PTM type |
Literature |
Database |
221 | Phosphothreonine. | Swiss-Prot 53.0 | 223 | Phosphotyrosine. | Swiss-Prot 53.0 | 223 | Phosphotyrosine (MAP2K4) | 15911620 | Phospho.ELM 6.0 |
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Methylation Profile [Top] | ||
There is no record for MAPK10 | ||