Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

5906

Name

RAP1A

Synonym

C21KG|G-22K|KREV-1|KREV1|RAP1|SMGP21;RAP1A, member of RAS oncogene family;RAP1A;RAP1A, member of RAS oncogene family

Definition

GTP-binding protein smg p21A|Ras-related protein Krev-1|ras-related protein Rap-1A

Position

1p13.3

Gene Type

protein-coding

TSG scores

Description

TUSON ranking

13826

TUSON P-value

1

Pathways and Diseases

Pathway

ARMS-mediated activation;PID Reactome;500631

Pathway

Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway;PANTHER;P00027

Pathway

Signaling events regulated by Ret tyrosine kinase;PID Curated;200058

Pathway

Neurotrophin signaling pathway;KEGG PATHWAY;hsa04722

Pathway

Diabetes pathways;Reactome;REACT:15380

Pathway

MAPK signaling pathway;KEGG PATHWAY;hsa04010

Pathway

Integrin cell surface interactions;Reactome;REACT:13552

Pathway

Class I PI3K signaling events;PID Curated;200098

Pathway

Focal adhesion;KEGG PATHWAY;hsa04510

Pathway

EPO signaling pathway;PID Curated;200157

Pathway

Reelin signaling pathway;PID Curated;200051

Pathway

Leukocyte transendothelial migration;KEGG PATHWAY;hsa04670

Pathway

Signalling by NGF;Reactome;REACT:11061

Pathway

TCR signaling in naive CD4+ T cells;PID Curated;200022

Pathway

Long-term potentiation;KEGG PATHWAY;hsa04720

Pathway

Frs2-mediated activation;PID Reactome;500630

Pathway

Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway;PANTHER;P00026

Pathway

Integrin signalling pathway;PANTHER;P00034

Pathway

Renal cell carcinoma;KEGG PATHWAY;hsa05211

Pathway

Pancreatic secretion;KEGG PATHWAY;hsa04972

Pathway

Hemostasis;Reactome;REACT:604

Pathway

Integration of energy metabolism;Reactome;REACT:1505

Pathway

Signaling in Immune system;Reactome;REACT:6900

Pathway

Chemokine signaling pathway;KEGG PATHWAY;hsa04062

Pathway

TCR signaling in naive CD8+ T cells;PID Curated;200062

Disease

Herpes;FunDO

Disease

Squamous cell cancer;FunDO

Disease

Emphysema;FunDO

Disease

Azoospermia;FunDO

Disease

Osteoporosis;NHGRI

Disease

Eating disorder;FunDO

External Links

Links to Entrez Gene

5906

Links to all GeneRIF Items

5906

Links to iHOP

5906

Sequence Information

The sequences provided here are only the longest representative sequences, not covering all the isoforms.

Nucleotide Sequence

>5906 : length: 555
atgcgtgagtacaagctagtggtccttggttcaggaggcgttgggaagtctgctctgaca
gttcagtttgttcagggaatttttgttgaaaaatatgacccaacgatagaagattcctac
agaaagcaagttgaagtcgattgccaacagtgtatgctcgaaatcctggatactgcaggg
acagagcaatttacagcaatgagggatttgtatatgaagaacggccaaggttttgcacta
gtatattctattacagctcagtccacgtttaacgacttacaggacctgagggaacagatt
ttacgggttaaggacacggaagatgttccaatgattttggttggcaataaatgtgacctg
gaagatgagcgagtagttggcaaagagcagggccagaatttagcaagacagtggtgtaac
tgtgcctttttagaatcttctgcaaagtcaaagatcaatgttaatgagatattttatgac
ctggtcagacagataaataggaaaacaccagtggaaaagaagaagcctaaaaagaaatca
tgtctgctgctctag

Protein Sequence

>5906 : length: 184
MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG
TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL
EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS
CLLL



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