Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

5906

Name

RAP1A

Synonymous

C21KG|G-22K|KREV-1|KREV1|RAP1|SMGP21;RAP1A, member of RAS oncogene family;RAP1A;RAP1A, member of RAS oncogene family

Definition

GTP-binding protein smg p21A|Ras-related protein Krev-1|ras-related protein Rap-1A

Position

1p13.3

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

Raf-1(m.s.) + Rap1A(h) <==> Raf-1(m.s.):Rap1A(h) (binding)
crk(h) + Rap1A(h) <==> crk(h):Rap1A(h) (binding)
RAP1A(h) --> Rap1A(h) (expression).
GP6(h) --> Rap1A(h) (activation)
RAP1A(h) --> Rap1A(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

181Cysteine methyl ester.Swiss-Prot 53.0
181S-geranylgeranyl cysteine.Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr1

Promoter: 111962428 - 111964428Agilent_014791

chr1

Promoter: 111962428 - 111964428GoldenGate_Methylation_Cancer_Panel_I

chr1

Promoter: 111962428 - 111964428GoldenGate_Methylation_Cancer_Panel_I

chr1

Promoter: 111962428 - 111964428GSE27584

chr1

Promoter: 111962428 - 111964428GSE27584


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