| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 6117 |
Name | RPA1 |
Synonym | HSSB|MST075|REPA1|RF-A|RP-A|RPA70;replication protein A1, 70kDa;RPA1;replication protein A1, 70kDa |
Definition | MSTP075|RF-A protein 1|RP-A p70|replication factor A protein 1|replication protein A 70 kDa DNA-binding subunit|single-stranded DNA-binding protein |
Position | 17p13.3 |
Gene Type | protein-coding |
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TSG scores |
Description |
| TUSON ranking | 14260 |
TUSON P-value | 1 |
|
Pathways and Diseases |
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Pathway | hypoxia and p53 in the cardiovascular system;PID BioCarta;100084 |
Pathway | Cell Cycle Checkpoints;Reactome;REACT:1538 |
Pathway | Homologous recombination;KEGG PATHWAY;hsa03440 |
Pathway | Mismatch repair;KEGG PATHWAY;hsa03430 |
Pathway | DNA replication;KEGG PATHWAY;hsa03030 |
Pathway | DNA Repair;Reactome;REACT:216 |
Pathway | Chromosome Maintenance;Reactome;REACT:22172 |
Pathway | Activation of the pre-replicative complex;PID Reactome;500981 |
Pathway | Cell Cycle, Mitotic;Reactome;REACT:152 |
Pathway | Nucleotide excision repair;KEGG PATHWAY;hsa03420 |
Pathway | atm signaling pathway;PID BioCarta;100235 |
Pathway | DNA Replication;Reactome;REACT:383 |
Disease | CANCER;GAD |
Disease | coronary spastic angina.;GAD |
Disease | CARDIOVASCULAR;GAD |
Disease | head and neck cancer lung cancer;GAD |
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External Links |
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Links to Entrez Gene | 6117 |
Links to all GeneRIF Items | 6117 |
Links to iHOP | 6117 |
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Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>6117 : length: 1851 atggtcggccaactgagcgagggggccattgcggccatcatgcagaagggggatacaaac ataaagcccatcctccaagtcatcaacatccgtcccattactacggggaatagtccgccg cgttatcgactgctcatgagtgatggattgaacactctatcctctttcatgttggcgaca cagttgaaccctctcgtggaggaagaacaattgtccagcaactgtgtatgccagattcac agatttattgtgaacactctgaaagacggaaggagagtagttatcttgatggaattagaa gttttgaagtcagctgaagcagttggagtgaagattggcaatccagtgccctataatgaa ggactcgggcagccgcaagtagctcctccagcgccagcagccagcccagcagcaagcagc aggccccagccgcagaatggaagctcgggaatgggttctactgtttctaaggcttatggt gcttcaaagacatttggaaaagctgcaggtcccagcctgtcacacacttctgggggaaca cagtccaaagtggtgcccattgccagcctcactccttaccagtccaagtggaccatttgt gctcgtgttaccaacaaaagtcagatccgtacctggagcaactcccgaggggaagggaag cttttctccctagaactggttgacgaaagtggtgaaatccgagctacagctttcaatgag caagtggacaagttctttcctcttattgaagtgaacaaggtgtattatttctcgaaaggc accctgaagattgctaacaagcagttcacagctgttaaaaatgactacgagatgaccttc aataacgagacttccgtcatgccctgtgaggacgaccatcatttacctacggttcagttt gatttcacggggattgatgacctcgagaacaagtcgaaagactcacttgtagacatcatc gggatctgcaagagctatgaagacgccactaaaatcacagtgaggtctaacaacagagaa gttgccaagaggaatatctacttgatggacacatccgggaaggtggtgactgctacactg tggggggaagatgctgataaatttgatggttctagacagcccgtgttggctatcaaagga gcccgagtctctgatttcggtggacggagcctctccgtgctgtcttcaagcactatcatt gcgaatcctgacatcccagaggcctataagcttcgtggatggtttgacgcagaaggacaa gccttagatggtgtttccatctctgatctaaagagcggcggagtcggagggagtaacacc aactggaaaaccttgtatgaggtcaaatccgagaacctgggccaaggcgacaagccggac tactttagttctgtggccacagtggtgtatcttcgcaaagagaactgcatgtaccaagcc tgcccgactcaggactgcaataagaaagtgattgatcaacagaatggattgtaccgctgt gagaagtgcgacaccgaatttcccaatttcaagtaccgcatgatcctgtcagtaaatatt gcagattttcaagagaatcagtgggtgacttgtttccaggagtctgctgaagctatcctt ggacaaaatgctgcttatcttggggaattaaaagacaagaatgaacaggcatttgaagaa gttttccagaatgccaacttccgatctttcatattcagagtcagggtcaaagtggagacc tacaacgacgagtctcgaattaaggccactgtgatggacgtgaagcccgtggactacaga gagtatggccgaaggctggtcatgagcatcaggagaagtgcattgatgtga |
Protein Sequence |
>6117 : length: 616 MVGQLSEGAIAAIMQKGDTNIKPILQVINIRPITTGNSPPRYRLLMSDGLNTLSSFMLAT QLNPLVEEEQLSSNCVCQIHRFIVNTLKDGRRVVILMELEVLKSAEAVGVKIGNPVPYNE GLGQPQVAPPAPAASPAASSRPQPQNGSSGMGSTVSKAYGASKTFGKAAGPSLSHTSGGT QSKVVPIASLTPYQSKWTICARVTNKSQIRTWSNSRGEGKLFSLELVDESGEIRATAFNE QVDKFFPLIEVNKVYYFSKGTLKIANKQFTAVKNDYEMTFNNETSVMPCEDDHHLPTVQF DFTGIDDLENKSKDSLVDIIGICKSYEDATKITVRSNNREVAKRNIYLMDTSGKVVTATL WGEDADKFDGSRQPVLAIKGARVSDFGGRSLSVLSSSTIIANPDIPEAYKLRGWFDAEGQ ALDGVSISDLKSGGVGGSNTNWKTLYEVKSENLGQGDKPDYFSSVATVVYLRKENCMYQA CPTQDCNKKVIDQQNGLYRCEKCDTEFPNFKYRMILSVNIADFQENQWVTCFQESAEAIL GQNAAYLGELKDKNEQAFEEVFQNANFRSFIFRVRVKVETYNDESRIKATVMDVKPVDYR EYGRRLVMSIRRSALM |